Precision Medicine, Crispr, and Genome Engineering: Moving from Association to Biology and Therapeutics, Tsang Stephen H.

Автор: Stephen Tsang; George M. Church
Название: Precision Medicine, CRISPR, and Genome Engineering
ISBN: 331963903X ISBN-13(EAN): 9783319639031
Издательство: Springer
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Цена: 19514.00 р.
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Описание: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine.

Автор: Bhattacharya Anjanabha, Parkhi Vilas, Char Bharat
Название: Crispr/Cas Genome Editing: Strategies and Potential for Crop Improvement
ISBN: 3030420213 ISBN-13(EAN): 9783030420215
Издательство: Springer
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Цена: 19514.00 р.
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Описание: This book offers a comprehensive collection of papers on CRISPR/Cas genome editing in connection with agriculture, climate-smart crops, food security, translational research applications, bioinformatics analysis, practical applications in cereals, floriculture crops, engineering plants for abiotic stress resistance, the intellectual landscape, regulatory framework, and policy decisions. Gathering contributions by internationally respected experts in the field of CRISPR/Cas genome editing, the book offers an essential guide for researchers, students, teachers and scientists in academia; policymakers; and public companies, private companies and cooperatives interested in understanding and/or applying CRISPR/Cas genome editing to develop new agricultural products.

Автор: Fulga Tudor A., Knapp David J. H. F., Ferry Quentin R. V.
Название: Crispr Guide RNA Design: Methods and Protocols
ISBN: 1071606867 ISBN-13(EAN): 9781071606865
Издательство: Springer
Цена: 15855.00 р.
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Описание: Beginning with a section on computational design of target-specific guide RNAs, the book continues by covering chemical modifications to alter guide RNA stability, specificity, and efficiency, as well as to create inducible guide RNAs, append additional functional domains, and express guide RNAs in a conditional manner.

Автор: M. Tofazzal Islam; Pankaj K. Bhowmik; Kutubuddin A
Название: CRISPR-Cas Methods
ISBN: 1071606158 ISBN-13(EAN): 9781071606155
Издательство: Springer
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Цена: 14635.00 р.
Наличие на складе: Нет в наличии.

Описание: Human trafficking is one of the most pressing social justice issues of our time. Though renewed interest in this issue among Christians is a wonderful thing, misinformed and misguided efforts can do more harm than good. Written by seasoned leaders and grounded in theology and up-to-date data, this accessible and compelling handbook will educate churches and organizations for truly effective work.

Автор: Mouldy Sioud
Название: RNA Interference and CRISPR Technologies
ISBN: 1071602896 ISBN-13(EAN): 9781071602898
Издательство: Springer
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Цена: 20123.00 р.
Наличие на складе: Нет в наличии.

Описание: This volume explores the uses of RNAi and CRISPR interferences as a general method for inhibiting gene expression, with focus on their biological functions, design, chemical modifications, delivery, and preclinical/clinical applications. In addition to relevant backgrounds, the chapters in this book discuss simple and accurate protocols dealing with the latest advances in RNAi and CRISPR applications and look at how these methods differ from one another. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, RNA Interference and CRISPR Technologies: Technical Advances and New Therapeutic Opportunities is a valuable resource for any scientist, teachers, graduate student, postdoc, and clinician interested in this field. This book also benefits anyone in research and development in biotech and pharmaceutical companies who want to understand more about these technologies, and their applications in biology and medicine.

Автор: Yonglun Luo
Название: CRISPR Gene Editing
ISBN: 1493991698 ISBN-13(EAN): 9781493991693
Издательство: Springer
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Цена: 21953.00 р.
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Описание: This detailed volume guides readers through strategic planning and user-friendly guidelines in order to select the most suitable CRISPR-Cas system and target sites with high activity and specificity. Methods covering CRISPR gRNA design, CRISPR delivery, CRISPR activity quantification (indel quantification), and examples of applying CRISPR gene editing in human pluripotent stem cells, primary cells, gene therapy, and genetic screening are included. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: Magnus Lundgren
Название: CRISPR : methods and protocols
ISBN: 1493926861 ISBN-13(EAN): 9781493926862
Издательство: Springer
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Цена: 20733.00 р.
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Описание: This volume presents a list of cutting-edge protocols for the study of CRISPR-Cas defense systems and their applications at the genomic, genetic, biochemical and structural levels. CRISPR: Methods and Protocols guides readers through techniques that have been developed specifically for the analysis of CRISPR-Cas and techniques adapted from standard protocols of DNA, RNA and protein biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, CRISPR: Methods and Protocols provides a broad list of tools and techniques to study the interdisciplinary aspects of the prokaryotic CRISPR-Cas defense systems.

Автор: M. D. Utpal Bhadra
Название: Microrna
ISBN: 1680539132 ISBN-13(EAN): 9781680539134
Издательство: Mare Nostrum (Eurospan)
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Цена: 17550.00 р.
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Описание: MicroRNA research and development is the billion-dollar baby and most lucrative option for drug discovery in gene therapy industries worldwide. Personalized microRNA treatments are in many cases the only remedy for viral diseases that have no cure in conventional drugs and offer to bring us closer than ever to “personalized medicine.” They also counteract cancer and other infectious and neuro-diseases. Early diagnosis, prognosis, staging, and sub-classification of various cancers can easily be facilitated by microRNA-based biomarkers. MicroRNA surveys recent advances in RNA and RNA-protein components that highlight RNA delivery, its stability, and applications of RNA-based drugs for the modulation of gene/protein expression and gene editing. The book not only focuses on the modern medicines of microRNA-based early diagnostic and therapy development, but also works as a hidden treasure for drug discovery of multiple rare diseases worldwide. It offers indispensable learning materials for academic researchers, graduate, and medical students, and offers a powerful practical guide for RNA-Pharma and gene therapy industries.