Описание: This volume is a collection of miRNA detection and target identification protocols, detailing new developments in the traditional detection approaches such as northern blot, quantitative real-time PCR, array, next generation sequencing, and in situ hybridization.
Автор: Malik Yousef; Jens Allmer Название: miRNomics: MicroRNA Biology and Computational Analysis ISBN: 1493962647 ISBN-13(EAN): 9781493962648 Издательство: Springer Рейтинг: Цена: 14635.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective.
Автор: Jian-Bing Fan Название: Next-Generation MicroRNA Expression Profiling Technology ISBN: 1493962175 ISBN-13(EAN): 9781493962174 Издательство: Springer Рейтинг: Цена: 17684.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The rapid pace of research in this field continues to drive technical advances that make methods more sensitive and applicable. This volume features many new methodologies described by leading researchers, including reproducible laboratory protocols.
Автор: Wei Wu Название: MicroRNA and Cancer ISBN: 1493974335 ISBN-13(EAN): 9781493974337 Издательство: Springer Рейтинг: Цена: 17074.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Part I: Review
1. Non- coding RNAs in DNA Damage Response: Opportunities for Cancer Therapeutics
Wani Arjumand, Asia Asiaf, and Shiekh Tanveer Ahmad
2. MicroRNAs in Breast Cancer: Diagnostic and Therapeutic Potential
Asia Asiaf, Shiekh Tanveer Ahmad, Wani Arjumand, and Mohammad Afzal Zargar
3. Involvement of miRNAs and Pseudogenes in Cancer
Lьtfi TUTAR, Aykut ЦZGЬR, and Yusuf TUTAR
4. microRNAs Reprogram Tumor Immune Response
Wenfang Cheng and Wei Wu
5. APOBEC Gene Expression Regulated by microRNAs
Wei Cao and Wei Wu
6. MicroRNAs Changes the Landscape of Cancer Resistance
Jun Zhu and Wei Wu
7. MicroRNA, Noise, and Gene Expression Regulation
Wei Wu
PART II: Protocol Section
8. Deep Sequencing Reveals a microRNA Expression Signature in
Triple-negative Breast Cancer
Yao-Yin Chang, Liang-Chuan Lai, Mong-Hsun Tsai, and Eric Y. Chuang
9. Detection of Plasma microRNA Signature in Osteosarcoma Patients
Wendy Allen-Rhoades and Jason T. Yustein
10. Identification of E6/E7-dependent microRNAs in HPV-positive Cancer Cells
Anja Honegger, Daniela Schilling, Holger Sьltmann, Karin Hoppe-Seyler, and Felix Hoppe-Seyler
11. Combination of Anti-miRNAs Oligonucleotides with Low Amounts of Chemotherapeutic Agents for Pancreatic Cancer Therapy
Marta Passadouro and Henrique Faneca
12. Evaluation of microRNA Delivery in vivo
Rikki A. M. Brown, Kirsty L. Richardson, Felicity C. Kalinowski, Michael R. Epis, Jessica L. Horsham, Tasnuva D. Kabir, Marisa H. De Pinho, Dianne J. Beveridge, Lisa M. Stuart, Larissa C. Wintle, and Peter J. Leedman
13. Angiogenesis A
nalysis by in vitro Co-culture Assays in Transwell Chambers in Ovarian Cancer
Ali Flores-Pйrez, Dolores Gallardo Rincуn, Erika Ruiz-Garcнa, Raquel Echavarria, Laurence A. Marchat, Elizbeth Бlvarez-Sбnchez, and Cйsar Lуpez-Camarillo
14. Application of Individual qPCR Performance Parameters for Quality Control of Circulating microRNA Data
Anna Brunet-Vega, Marнa Elisa Quнlez, Marнa Josй Ramнrez-Lбzaro, andSergio Lario
15. Construction of Multi-potent microRNA Sponge and its Functional Evaluation
Suhwan Chang
16. microRNA Sequencing Data Analysis Toolkits
Wei Wu
Автор: Xueji Zhang; Haifeng Dong; Yaping Tian Название: MicroRNA Detection and Pathological Functions ISBN: 3662472929 ISBN-13(EAN): 9783662472927 Издательство: Springer Рейтинг: Цена: 6707.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes microRNA (miRNA) biology in a variety of pathological processes, emphasizing the significant potential applications of miRNA in diagnostics and prognostics, as well as novel drug targets. The conventional techniques used for miRNA detection including standard PCR, Northern blotting, microarray and clone methods are addressed. Recent emerging strategies in miRNA detection and quantification with superior flexibility and adaptability, such as novel molecular biological techniques and locked nucleic acid (LNA) modified probes, as well as nanotechnology-based approaches, are also included. The book also highlights the latest advances in clinical-related miRNA detection methods in living cells, circulating blood and tissue, such as in situ hybridization (ISH) and molecular imaging techniques, which are useful to elucidate the biogenesis and biological function of miRNAs in vivo. Finally, the respective advantages and drawbacks of various detection techniques in this fast-moving field are discussed, along with the challenges and promising new directions. This book offers a valuable resource for analytical chemists, biologists and physicians involved in miRNA research. Dr. Xueji Zhang and Dr. Haifeng Dong are Professors at the School of Chemistry & Biological Engineering, University of Science & Technology Beijing (USTB), China. Dr. Yaping Tian is a Professor at the Department of Clinical Biochemistry, Chinese PLA General Hospital and Military Medical School, China.
Автор: Zengrong Liu; Jianwei Shen; Shuiming Cai; Fang Yan Название: MicroRNA Regulatory Network: Structure and Function ISBN: 9402415750 ISBN-13(EAN): 9789402415759 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses topics related to the topological structure and biological function of gene networks regulated by microRNAs. It focuses on analyzing the relation between topological structure and biological function, applying these theoretical results to gene networks involving microRNA, illustrating their biological mechanisms, and identifying the roles of microRNA in controlling various phenomena emerging from the networks. In addition, the book explains how to control the complex biological phenomena using mathematical tools and offers a new perspective on studying microRNA. It is a useful resource for graduate students and researchers who are working on or interested in microRNAs and gene network.
Автор: Suresh Alahari Название: MicroRNA in Cancer ISBN: 9401784930 ISBN-13(EAN): 9789401784931 Издательство: Springer Рейтинг: Цена: 13677.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explores the rapidly emerging field of microRNA biology, highlighting the importance of microRNAs in cancer. This first reference of its kind will benefit working scientists in cancer biology, as well as advanced undergraduate and graduate students.
Название: Regulatory microRNA ISBN: 3038977683 ISBN-13(EAN): 9783038977681 Издательство: Неизвестно Рейтинг: Цена: 11918.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book includes updated information about microRNA regulation, for example, in the fields of circular RNAs, multiomics analysis, biomarkers and oncogenes. The variety of topics included in this book reaffirms the extent to which microRNA regulation affects biological processes. Although microRNAs are not translated to proteins, their importance for biological processes is not less than proteins. An understanding of their roles in various biological processes is critical to understanding gene function in these biological processes. Although non-coding RNAs other than microRNAs have recently come under investigation, microRNA still remains the front runner as the subject of genetic and biological studies. In reading the collection of papers, readers can grasp the most updated information regarding microRNA regulation, which will continue to be an important topic in genetics and biology.
Автор: Malik Yousef; Jens Allmer Название: miRNomics: MicroRNA Biology and Computational Analysis ISBN: 1627037470 ISBN-13(EAN): 9781627037471 Издательство: Springer Рейтинг: Цена: 13415.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective.
Автор: Shao-Yao Ying Название: MicroRNA Protocols ISBN: 1617376566 ISBN-13(EAN): 9781617376566 Издательство: Springer Рейтинг: Цена: 22563.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: MicroRNA Protocols provides diverse, novel, and useful descriptions of miRNAs in several species, including plants, worms, flies, fish, chicks, mice, and humans. These include some useful adaptations and applications that could be relevant to the wider research community who are already familiar with the identification of miRNAs.
Автор: Baohong Zhang; Edmund J. Stellwag Название: RNAi and microRNA-Mediated Gene Regulation in Stem Cells ISBN: 149395749X ISBN-13(EAN): 9781493957491 Издательство: Springer Рейтинг: Цена: 17074.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent stem cell research has revealed that miRNA and RNAi-mediated gene regulation is one of the vital determinates controlling the state of cell differentiation, with the small RNAs serving as key elements involved in regulatory network control of pluripotent cell fate determination. In RNAi and microRNA-Mediated Gene Regulation in Stem Cells: Methods, Protocols, and Applications, expert authors from laboratories across the globe contribute an accessible compendium of up-to-date, proven methods focused on the study of the titular topic. Divided into three sections, the book first gives a brief introduction to RNAi and miRNAs in stem cells, with a focus on the current status of research and future perspectives, then it continues with detailed methods and protocols for RNAi screening, transfection, and the knockdown of specific genes and pathways in several animal species, including humans and mice, concluding with a section on recently developed methods for identification of miRNAs, including a general protocol for preparation and analysis of miRNA libraries for deep sequencing, knock down of a specific gene using miRNA-based shRNA, and miRNA expression analysis using qRT-PCR. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes highlighting tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, RNAi and microRNA-Mediated Gene Regulation in Stem Cells: Methods, Protocols, and Applications serves as a valuable resource for scientists and aspiring graduate students interested in the intersection of RNAi, miRNA, and stem cell molecular biology and the exciting areas of medicine, including regenerative medicine, aging, cancer, and neurological disorders, that can be advanced through this expanding area of research.
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