CRISPR-Cas Methods, M. Tofazzal Islam; Pankaj K. Bhowmik; Kutubuddin A
Автор: Fulga Tudor A., Knapp David J. H. F., Ferry Quentin R. V. Название: Crispr Guide RNA Design: Methods and Protocols ISBN: 1071606867 ISBN-13(EAN): 9781071606865 Издательство: Springer Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Beginning with a section on computational design of target-specific guide RNAs, the book continues by covering chemical modifications to alter guide RNA stability, specificity, and efficiency, as well as to create inducible guide RNAs, append additional functional domains, and express guide RNAs in a conditional manner.
Автор: Stephen Tsang; George M. Church Название: Precision Medicine, CRISPR, and Genome Engineering ISBN: 331963903X ISBN-13(EAN): 9783319639031 Издательство: Springer Рейтинг: Цена: 19514.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine.
Автор: Mouldy Sioud Название: RNA Interference and CRISPR Technologies ISBN: 1071602896 ISBN-13(EAN): 9781071602898 Издательство: Springer Рейтинг: Цена: 20123.00 р. Наличие на складе: Нет в наличии.
Описание: This volume explores the uses of RNAi and CRISPR interferences as a general method for inhibiting gene expression, with focus on their biological functions, design, chemical modifications, delivery, and preclinical/clinical applications. In addition to relevant backgrounds, the chapters in this book discuss simple and accurate protocols dealing with the latest advances in RNAi and CRISPR applications and look at how these methods differ from one another. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, RNA Interference and CRISPR Technologies: Technical Advances and New Therapeutic Opportunities is a valuable resource for any scientist, teachers, graduate student, postdoc, and clinician interested in this field. This book also benefits anyone in research and development in biotech and pharmaceutical companies who want to understand more about these technologies, and their applications in biology and medicine.
Описание: This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.
Описание: This book addresses the function of international science through a detailed study of international congresses in genetics held from 1899-1939.
Автор: Chittaranjan Kole; Pablo Rabinowicz Название: The Castor Bean Genome ISBN: 3319972790 ISBN-13(EAN): 9783319972794 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book addresses various aspects of the current castor bean research, including genetics, biotechnology, comparative genomics, and more specific topics such as oil metabolism and the ricin toxin. It also presents the whole genome sequencing of the castor bean and its impact on the mining of gene families and future plant breeding.
Castor bean (Ricinus communis), an oilseed plant, belongs to the Euphorbiaceae (spurge) family. It is a tropical and subtropical crop valued for the high quality and uniform nature of its oil, which is mostly composed of the uncommon fatty acid ricinoleate. Castor bean oil has important industrial applications for the production of lubricants, cosmetics, medicines, and specialty chemicals, and castor bean has also been proposed as a biodiesel crop that does not pose concerns regarding the “food versus fuel” debate. However, it accumulates the type 2 ribosome-inactivating protein ricin in its seeds, and health concerns posed by ricin’s high toxicity have prevented broader cultivation. Recently, there has been renewed interest in castor bean due to potential biosecurity issues.
Автор: Marco A. Zarbin; Mandeep S. Singh; Ricardo P. Casa Название: Cell-Based Therapy for Degenerative Retinal Disease ISBN: 3030052214 ISBN-13(EAN): 9783030052218 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses why specific diseases are being targeted for cell-based retinal therapy, what evidence exists that justifies optimism for this approach, and what challenges must be managed in order to bring this technology from the laboratory into routine clinical practice. There are a number of unanswered questions (e.g., surgical approach to cell delivery, management of immune response, optimum cell type to transplant) that very likely are not going to be answered until human trials are undertaken, but there is a certain amount of “de-risking” that can be done with preclinical experimentation. This book is essential reading for scientists, clinicians, and advanced students in stem cell research, cell biology, and ophthalmology.
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