Автор: Cromm, P Название: Inducing targeted protein degradation ISBN: 3527350136 ISBN-13(EAN): 9783527350131 Издательство: Wiley Рейтинг: Цена: 19800.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: When the author`s two children (a boy and a girl) were young, they often crawled into bed with his wife and him in the morning, he would make up stories about two little mice, Ticklemouse and his friend Lively, who lived in the same house as the little boy or girl, depending on who was listening. Ticklemouse was the author`s right hand and Lively his left, and they loved to tickle the kids whenever the mice got excited during the story. He never knew where the stories would go as he made them up, but over time, several were repeated often enough that they became memorable. When his kids grew up and had kids of their own, the author wrote down four of the stories and discovered that they were just as popular with his grandkids. These stories of shared laughter and fun became The Adventures of Ticklemouse. The author hopes you and your children or grandchildren enjoy them as much as his did and still do.
Автор: Ayad M. Fadhil Al-Quraishi, Yaseen T. Mustafa, Abd Название: Environmental Degradation in Asia ISBN: 3031121112 ISBN-13(EAN): 9783031121111 Издательство: Springer Рейтинг: Цена: 18904.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This unique book focuses on environmental degradation in Asian countries including land degradation and soil erosion. The land degradation covers assessing environmental degradation using geospatial technology, land use land cover mapping, environmental and anthropogenic degradation, assessment of land degradation vulnerability, evaluation of the impact of earthquake and the environmental control of the sand dunes. It also addresses the soil degradation and environmental pollution and presents several case studies such as tectonic activity and erosion, assessment of aircraft sound, soil degradation assessment for the arid territories, soil pollution, waste engine oil contamination, soil degradation, soil erosion modelling, land use and land cover change and its effect on soil erosion changes. Additionally, the book discusses the impact of climate change, and human activities including urban environmental quality, air pollution and the impact of armed conflict on the environment. Moreover, topics such as vegetation degradation including forest changes, hydrological and agricultural drought are presented. The book includes authors and scientists from Egypt, Iraq, Iran, India, Mongolia, United Arab Emirates, Uzbekistan, Republic of Kazakhstan, USA, Turkey, South Africa, Italy, China, Malaysia, Poland and Russia. Graduate students, researchers, engineers, policy planners, policymakers and stockholders could benefit from the information and the knowledge in this book.
Автор: Burslem,George Название: Targeted Protein Degradation,681 ISBN: 0323992005 ISBN-13(EAN): 9780323992008 Издательство: Elsevier Science Рейтинг: Цена: 23244.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Michele Reboud-Ravaux Название: Protein Degradation in Health and Disease ISBN: 3642627145 ISBN-13(EAN): 9783642627149 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Deshaies, Raymond J. Название: Ubiquitin and Protein Degradation, Part B ISBN: 0121828042 ISBN-13(EAN): 9780121828042 Издательство: Elsevier Science Рейтинг: Цена: 26275.00 р. Наличие на складе: Нет в наличии.
Автор: Dice, J Fred Название: Lysosomal Pathways of Protein Degradation ISBN: 1587060035 ISBN-13(EAN): 9781587060038 Издательство: Taylor&Francis Рейтинг: Цена: 30624.00 р. Наличие на складе: Нет в наличии.
Автор: Cacace Angela M., Hickey Christopher M., Bйkйs Miklуs Название: Targeted Protein Degradation: Methods and Protocols ISBN: 1071616641 ISBN-13(EAN): 9781071616642 Издательство: Springer Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed book aims to provide an overview of novel bioinformatics resources for exploring diverse aspects of RNA biology. This edition focuses on methods dealing with non-coding RNA (miRNAs, circRNAs or lncRNAs), RNA modifications (m6A or RNA editing), single cell RNA-seq and statistical models to handle count data from RNA-seq experiments.
Автор: Friedman, Laurie Название: Targeted Protein Degradation ISBN: 1071616676 ISBN-13(EAN): 9781071616673 Издательство: Springer Рейтинг: Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume explores molecularly imprinted polymers (MIPs), which have attracted great interest both in fundamental research and for practical applications due to their selective molecular recognition capabilities, extraordinary stability, and ease of preparation.
Автор: Hochstrasser, Mark Название: Hochstrasser-Ubiquitin-Dependent Protein Degradation V619 ISBN: 0128186674 ISBN-13(EAN): 9780128186671 Издательство: Elsevier Science Рейтинг: Цена: 26275.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Ubiquitination and Protein Stability - Part B, Volume 619, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors. Topics of note include chapters on Assays of SUMO protease function in mammalian cells, In vitro analysis of proteasome-associated USP14 activity for substrate degradation and deubiquitylation, Methods to study proteasome regulatory particle assembly, Native mass spectrometry approaches to study the proteasome, Single-molecule methods to study the ubiquitin-proteasome system, Assays for the function of ubiquitin in the mammalian endocytic pathway, and much more.
Provides the authority and expertise of leading contributors from an international board of authors
Presents the latest release in this series on enzymology
Molecular chaperones are a fundamental group of proteins that have been identified only relatively recently. They are key components of a protein quality machinery in the cell which insures that the folding process of any newly-synthesized polypeptide chain results in the formation of a properly folded protein and that the folded protein is maintained in an active conformation throughout its functional lifetime. Molecular chaperones have been shown to play essential roles in cell viability under both normal and stress conditions. Chaperones can also assist in the unfolding and degradation of misfolded proteins and in disaggregating preformed protein aggregates. Chaperones are also involved in other cellular functions including protein translocation across membranes, vesicle fusion events, and protein secretion.
In recent years, tremendous advances have been made in our understanding of the biology, biochemistry, and biophysics of function of molecular chaperones. In addition, recent technical developments in the fields of proteomics and genomics allowed us to obtain a global view of chaperone interaction networks. Finally, there is now a growing interest in the role of molecular chaperones in diseases.
This book will provide a comprehensive analysis of the structure and function of the diverse systems of molecular chaperones and their role in cell stress responses and in diseases from a global network perspective.
Автор: Peter Zwickl; Wolfgang Baumeister Название: The Proteasome — Ubiquitin Protein Degradation Pathway ISBN: 3642639712 ISBN-13(EAN): 9783642639715 Издательство: Springer Рейтинг: Цена: 15957.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The penultimate chapter rounds up the in- formation on intracellular distribution of proteasomes in yeast and mammalian cells, while the last contribution highlights proteasome inhibitors, tools which proved to be very valuable for dissecting the cellular roles of the proteasome and which might turn out to be of pharmacological importance.
Автор: Bowring, Bill Название: The Degradation of the International Legal Order? ISBN: 1904385990 ISBN-13(EAN): 9781904385998 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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