Автор: Asim Kumar, Gaurav Joshi, Mayank Sharma, Ramarao Poduri Название: Drug Repurposing ISBN: 3110791528 ISBN-13(EAN): 9783110791525 Издательство: Walter de Gruyter Рейтинг: Цена: 129983.00 р. Наличие на складе: Нет в наличии.
Описание:
Drug repurposing, or drug repositioning, or reprofiling, has emerged as a valid approach in modern drug discovery. The book describes tools and techniques for identifying new therapeutic potentials for existing drugs and covers the repurposing of drugs from synthetic and natural origin. It compares the costs of drug repurposing with traditional drug discovery and discusses challenges and future perspectives of drug repurposing.
Название: Drug Repurposing and Computational Drug Discovery ISBN: 1774912775 ISBN-13(EAN): 9781774912775 Издательство: Taylor&Francis Рейтинг: Цена: 22509.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and in silico approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning.
Описание: This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and in silico approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning.
Описание: Drug repurposing (or drug repositioning) is defined as the process of identifying new pharmacological indications of old, existing, investigational, or FDA-approved drugs for use in the treatment of diseases other than the drugs' original intended therapeutic use. Drug Repurposing: Advances, Scopes and Opportunities in Drug Discovery delivers up-to-date information on the identification of newer uses, molecular mechanisms, and novel targets of existing drug candidates through the application of various experimental, biophysical, and computational approaches and techniques. Chapters discuss recent advances in drug repurposing strategies that are currently being used in the discovery and development of drugs against difficult-to-treat, rare, and life-threatening diseases, including microbial infections, COVID-19, parasitic diseases, cardiovascular diseases, neurological disorders, and cancer. The book also discusses the modern experimental assays (HTS) and computational techniques including informatics and databases, molecular docking and dynamics, artificial intelligence and machine learning, virtual screening and pharmacophore modelling, proteomics and metabolomics, and network pharmacology and systems biology approaches. Some of the key features of the book are:
Presents the strategies available for the development of drugs by drug repurposing approaches through various experimental and computational techniques for the treatment of difficult-to-treat, rare, and deadly diseases.
Summarises the latest advances in the application of drug repurposing strategies, techniques, and approaches in the discovery and development of drugs.
Depicts drug development approaches from existing drug candidates and/or lead molecules through modern experimental assays, biophysical tools, and computational techniques.
Written by a global team of experts, this book is useful for drug discovery scientists, drug developers, medicinal chemists, phytochemists, pharmacologists, clinicians, biochemists, biomedical scientists, healthcare professionals, researchers, teaching faculty, and students.
Автор: Asim Kumar, Gaurav Joshi, Mayank Sharma, Ramarao Poduri Название: Drug Repurposing ISBN: 3110791145 ISBN-13(EAN): 9783110791143 Издательство: Walter de Gruyter Рейтинг: Цена: 13937.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Drug repurposing, or drug repositioning, or reprofiling, has emerged as a valid approach in modern drug discovery. The book describes tools and techniques for identifying new therapeutic potentials for existing drugs and covers the repurposing of drugs from synthetic and natural origin. It compares the costs of drug repurposing with traditional drug discovery and discusses challenges and future perspectives of drug repurposing.
Автор: Singh,Vijai Название: New Approach For Drug Repurposing Part A,205 ISBN: 0443223386 ISBN-13(EAN): 9780443223389 Издательство: Elsevier Science Рейтинг: Цена: 20043.00 р. Наличие на складе: Нет в наличии.
Автор: Roy, Kunal Название: In Silico Drug Design ISBN: 0128161256 ISBN-13(EAN): 9780128161258 Издательство: Elsevier Science Рейтинг: Цена: 23075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the inclusion of practical case studies, this book gives scientists, researchers and R&D professionals in the pharmaceutical industry valuable insights into drug design.
Discusses the theoretical background and methodologies of useful techniques of cheminformatics and bioinformatics that can be applied for drug repurposing
Offers case studies relating to the in silico modeling of FDA-approved drugs for the discovery of antifungal, anticancer, antiplatelet agents, and for drug therapies against diseases
Covers tools and databases that can be utilized to facilitate in silico methods for drug repurposing
Название: Computational methods for drug repurposing ISBN: 1493989545 ISBN-13(EAN): 9781493989546 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed book explores techniques commonly used for research into drug repurposing, a well-known strategy to find alternative indications for drugs which have already undergone toxicology and pharma-kinetic studies but have failed later stages during the development, via computational methods. Thereby, it addresses the intense challenges of identifying the appropriate type of algorithm and relevant technical information for computational repurposing. Written for the highly successful Methods in Molecular Biology series, the authors of each chapter use their experience in the field to describe the implementation and successful use of a specific repurposing method thus providing lab-ready instruction.
Authoritative and practical, Computational Methods for Drug Repurposing serves as an ideal guide to researchers interested in this vital area of drug development.
Автор: Cavalla David Название: Drug Repurposing ISBN: 1788019032 ISBN-13(EAN): 9781788019033 Издательство: Royal Society of Chemistry Рейтинг: Цена: 45923.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Drug Repurposing provides an ideal introduction to the field of drug repositioning and repurposing with contributions from world-renowned experts culminating in an excellent resource for any drug discovery or medicinal chemist.
Автор: Love, Janine Название: Rf Front-End: World Class Designs ISBN: 1856176223 ISBN-13(EAN): 9781856176224 Издательство: Elsevier Science Рейтинг: Цена: 7409.00 р. Наличие на складе: Нет в наличии.
Описание: Covers the gamut of RF front end design from antenna and filter design fundamentals to optimized layout techniques. This book discusses various approaches to solving RF front end design problems and how to successfully apply theory to actual design tasks.
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