Описание: New materials and manufacturing techniques are emerging with potential to address the challenges associated with the manufacture of pharmaceutical systems that will teach new tricks to old drugs. 3D printing (3DP) is a technique that can used for the manufacturing of dosage forms, and especially targeting paediatric and geriatric formulations, as permits the fabrication of high degrees of complexity with great reproducibility, in a fast and cost-effective fashion, and offers a new paradigm for the direct manufacture of personalised dosage forms. The book is covering the basics behind each additive manufacturing (AM) method, current applications in pharmaceutics for each 3DP method, and case studies (examples) from a teaching perspective, targeting undergraduate (UG) and postgraduate (PG) students. A unique to this book is the integration of studies based upon the use of different AM technologies, which designed to reinforce importance printing parameters and material considerations. The book includes case studies or multiple-choice questions (MCQs), which allow application of the content in a flipped-classroom.
Описание: This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM).
Автор: Coelho Jorge Название: Drug Delivery Systems: Advanced Technologies Potentially App ISBN: 9400760094 ISBN-13(EAN): 9789400760097 Издательство: Springer Рейтинг: Цена: 25077.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focuses on the theme of "Drug delivery systems: advanced technologies potentially applicable in personalised treatments". In this title, the critical topics involving the development and preparation of effective drug delivery systems, such as: polymers available, three dimensional structures, and technological tendencies, are carefully discussed.
Описание: This book is intended for periodontal residents and practicing periodontists who wish to incorporate the principles of moderate sedation into daily practice. Comprehensive airway management and rescue skills are then documented in detail so that the patient may be properly managed in the event that the sedation progresses beyond the intended level.
Автор: Meral ?zg?? Название: Rare Diseases ISBN: 9401792135 ISBN-13(EAN): 9789401792134 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on predictive, preventative and personalized medicine (PPPM) and how it is related to the healthcare of rare diseases. Chapters look at national plans for rare disease, at biobanking, gene identification, rare cancers, virus gene therapy , induced pluripotency for cell therapy amongst other topics.
Название: Personalised health care ISBN: 3030523985 ISBN-13(EAN): 9783030523985 Издательство: Springer Рейтинг: Цена: 6097.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction (Boccia) 1. Chapter 1: Identification of biomarkers for the prevention of chronic disease (Editors: Adany, Boccia). 1.1 Van Duijn (Identification of biomarkers for primary and secondary prevention - Liu)1.2 Boccia (Identification of biomarkers for tertiary prevention - Mariani, Giraldi, Pastorino)1.3 Adany (Application of Single-Nucleotide Polymorphism-Related Risk Estimates in Identification of Increased Genetic Susceptibility to Specific Diseases)1.4 Giordano Bottа - Allelica (Non Academic Vision) Recommendation 1 Personalised interventions for the prevention of chronic diseases require robust evidence of efficacy and/or effectiveness of the new technology when implemented in health care. 2. Chapter 2: Evaluation of predictive genomic applications (Editor: Villari) 2.1 The economic evaluation of genetic/genomic applications (D'Andrea)2.2 The HTA approach for the evaluation of genetic/genomic applications (Pitini)2.3 Training needs in genomics of Public Health Professionals (Rosso) Recommendation 2A comprehensive evaluation of the value (outcomes/cost) of the new technology should also include evidence on the social aspects, and context-related dimensions to better support the clinical decision-making process. Genetic or genomic applications with evidence of efficacy, effectiveness, and cost-effectiveness should be implemented in clinical and public health practice. 3. Chapter 3: Ethico-legal and policy issues surrounding personalised medicine (Editor: Sandor) 3.1 Zawati (Ethical issue) 3.2 Calabro, Hoxaij, Boccia (Policy issue, with a focus on training in genomics for healthcare professionals)3.3 Calabro, Sassano, Boccia (Policy issue, with a focus on citizens and DTC)3.4 Sandor (Legal issue) Recommendation 3The era of genomics requires that we clarify and validate the obligations and responsibilities of the research community, research participants, and the general public including patients through collaboration and dissemination of high-quality ethical, policy, and legal analysis. 4. Chapter 4: Roles and responsibilities of stakeholders in informing healthy individuals on their genome: a sociotechnical analysis (Editor: Cornel) (Martina Cornel, Tessel Rigter, and Carla van El)4.1 Responsible translation of new genomic technologies in the context of screening of healthy adults4.2 Examples from hereditary cardiovascular diseases and hereditary cancers Recommendation 4 A dedicated effort is necessary to stimulate further implementation of evidence-based interventions in health care, such as testing of family members in cases of hereditary cancers or cardiovascular diseases. 5. Chapter 5: Identification of organizational models for the provision of predictive genomic applications (Editor: De Vito) 5.1 De Vito/Unim (Delivery models for genetic/genomic applications)5.2 Cornel (Barriers and Facilitating Factors for Implementation of Genetic Services)5.3 Gray/Jani (Design systems that integrate genomic information to deliver personalised care)5.4 Roldan (Clinical decision support tool to assist physicians in the screening of genetic diseases) Recommendation 5 The integration of genomic sciences in other medical spec
Описание: This volume presents advanced bio/medical sciences with a particular value for translating research achievements into daily medical practice in the framework of Predictive, Preventive and Personalised Medicine (3PM/PPPM). First two decades of the 21st century are characterised by epidemics of non-communicable diseases such as many hundreds of millions of patients diagnosed with cardiovascular diseases and the type 2 diabetes mellitus, breast, lung, liver and prostate malignancies, neurological, sleep, mood and eye disorders, amongst others. Consequent socio-economic burden is tremendous. Unprecedented decrease in age of maladaptive individuals has been reported. The absolute majority of expanding non-communicable disorders carry a chronic character, over a couple of years progressing from reversible suboptimal health conditions to irreversible severe pathologies and cascading collateral complications. The paradigm change from reactive to predictive preventive and personalisedmedicine is essential to promote population health by application of individualised patient profiling, multi-parametric analysis leading to cost-effective targeted prevention. To this end, inadequate data for risk assessment on speed and urgency of COVID-19, combined with increased globalization of human society, led to the rapid spread of COVID-19. Despite an abundance of digital methods that could be used in slowing or stopping this virus and future pandemics, the world remains unprepared, and lessons have not been learned from previous cases of pandemics. The book presents PPPM strategies which might be of great clinical utility for future pandemics. In a long-term way, a significantly improved healthcare economy is one of the clear benefits of the proposed paradigm shift; a tight collaboration between all stakeholders including scientific community, healthcare providers, patient organisations, policy-makers and educators is analysed for the smooth implementationof the 3PM concepts. Further issues linked to big data management and medical ethics have to be carefully treated in the context of application of artificial intelligence in medicine.
Автор: Godfrey Grech; Iris Grossman Название: Preventive and Predictive Genetics: Towards Personalised Medicine ISBN: 3319153439 ISBN-13(EAN): 9783319153438 Издательство: Springer Рейтинг: Цена: 19514.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Pharmacogenomics supports personalized medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalized medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.
Автор: Vincenzo Costigliola Название: Healthcare Overview ISBN: 9400799217 ISBN-13(EAN): 9789400799219 Издательство: Springer Рейтинг: Цена: 25075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In healthcare, the realisation of an optimistic prognosis against pessimistic ones depends on current innovations in diagnostic and cost-effective treatment approaches being widely adopted in clinical practice.
Автор: Olga Golubnitschaja Название: Flammer Syndrome ISBN: 3030135527 ISBN-13(EAN): 9783030135522 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Нет в наличии.
Автор: van Dijk, Boyd (McKenzie Fellow, Melbourne Law School, Australia) Название: Trigeminal Neuralgia and Other Cranial Neuralgias ISBN: 0198871600 ISBN-13(EAN): 9780198871606 Издательство: Oxford Academ Рейтинг: Цена: 7869.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: 36 recognised experts from nine countries have contributed to OPML Trigeminal Neuralgia and Other Cranial Neuralgias to guide you through the maze of pathophysiology, clinical features, diagnosis-making, and condition-specific treatments.
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