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Halina Podbielska Predictive, Preventive, and Personalised Medicine: From Bench to Bedside 9783031348860
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Predictive, Preventive, and Personalised Medicine: From Bench to Bedside, Halina Podbielska


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Автор: Halina Podbielska
Название:  Predictive, Preventive, and Personalised Medicine: From Bench to Bedside
ISBN: 9783031348860
Издательство: Springer
Классификация:

ISBN-10: 3031348869
Обложка/Формат: Soft cover
Страницы: 348
Вес: 0.00 кг.
Дата издания: 14.11.2024
Язык: English
Ключевые слова: Health Promotion and Disease Prevention,Biomarkers, Biomedical Research
Основная тема: Biomedical and Life Sciences
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This volume presents advanced bio/medical sciences with a particular value for translating research achievements into daily medical practice in the framework of Predictive, Preventive and Personalised Medicine (3PM/PPPM). First two decades of the 21st century are characterised by epidemics of non-communicable diseases such as many hundreds of millions of patients diagnosed with cardiovascular diseases and the type 2 diabetes mellitus, breast, lung, liver and prostate malignancies, neurological, sleep, mood and eye disorders, amongst others. Consequent socio-economic burden is tremendous. Unprecedented decrease in age of maladaptive individuals has been reported. The absolute majority of expanding non-communicable disorders carry a chronic character, over a couple of years progressing from reversible suboptimal health conditions to irreversible severe pathologies and cascading collateral complications. The paradigm change from reactive to predictive preventive and personalisedmedicine is essential to promote population health by application of individualised patient profiling, multi-parametric analysis leading to cost-effective targeted prevention. To this end, inadequate data for risk assessment on speed and urgency of COVID-19, combined with increased globalization of human society, led to the rapid spread of COVID-19. Despite an abundance of digital methods that could be used in slowing or stopping this virus and future pandemics, the world remains unprepared, and lessons have not been learned from previous cases of pandemics. The book presents PPPM strategies which might be of great clinical utility for future pandemics. In a long-term way, a significantly improved healthcare economy is one of the clear benefits of the proposed paradigm shift; a tight collaboration between all stakeholders including scientific community, healthcare providers, patient organisations, policy-makers and educators is analysed for the smooth implementationof the 3PM concepts. Further issues linked to big data management and medical ethics have to be carefully treated in the context of application of artificial intelligence in medicine.
Дополнительное описание: Preface.- 1. PPPM innovation in primary, secondary, and tertiary care.- 2. Suboptimal Health Innovation: From Bench to Bedside.- 3. What is the routine mitochondrial health check-up good for? A holistic  approch in the framework of 3P



Zipes and Jalife`s Cardiac Electrophysiology: From Cell to Bedside, 8th Edition

Автор: Jalife Stevenson
Название: Zipes and Jalife`s Cardiac Electrophysiology: From Cell to Bedside, 8th Edition
ISBN: 0323757456 ISBN-13(EAN): 9780323757454
Издательство: Elsevier Science
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Цена: 36211.00 р.
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Описание: Fully updated from cover to cover, Zipes and Jalife's Cardiac Electrophysiology: From Cell to Bedside, 8th Edition, provides the comprehensive, multidisciplinary coverage you need-from new knowledge in basic science to the latest clinical advances in the field. Drs. Jose Jalife and William Gregory Stevenson lead a team of global experts who provide cutting-edge content and step-by-step instructions for all aspects of cardiac electrophysiology.

Packs each chapter with the latest information necessary for optimal basic research as well as patient care. Covers new technologies such as CRISPR, protein research, improved cardiac imaging, optical mapping, and wearable devices. Contains significant updates in the areas of molecular biology and genetics, iPSCs (induced pluripotent stem cells), embryonic stem cells, precision medicine, antiarrhythmic drug therapy, cardiac mapping with advanced techniques, and ablation technologies including stereotactic radioablation.

Includes 47 new chapters covering both basic science and clinical topics. Discusses extensive recent progress in the understanding, diagnosis, and management of arrhythmias, including new clinical insights on atrial fibrillation and stroke prevention, new advances in the understanding of ventricular arrythmias in genetic disease, and advances in implantable devises and infection management. Features 1,600 high-quality photographs, anatomic and radiographic images, electrocardiograms, tables, algorithms, and more., with additional figures, tables, and videos online.

Recipient of a 2018 Highly Commended award from the British Medical Association. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment

Автор: Jorge Coelho
Название: Drug Delivery Systems: Advanced Technologies Potentially Applicable in Personalised Treatment
ISBN: 9400794150 ISBN-13(EAN): 9789400794153
Издательство: Springer
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Цена: 19376.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This book is part of a series dedicated to recent advances on preventive, predictive and personalised medicine (PPPM).

Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future

Автор: Silvia Mandel
Название: Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future
ISBN: 9400792956 ISBN-13(EAN): 9789400792951
Издательство: Springer
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Цена: 19376.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание:

Part I

1. What is this book series about? Foreword of Book Series Editor; O. Golubnitschaja

2. Preface; S. Mandel

3. Introductory chapter; S. Mandel and O. Golubnitschaja

Part II

4. Individual predispositions in healthy vasospastic individuals: Patient profiling for targeted prevention of "down-stream" pathologies as cost-effective personalised medicine; K. Yeghiazaryan, J. Flammer, O. Golubnitschaja

5. Idiopathic REM sleep behavior disorder as a long-term predictor of neurodegenerative disorders; S. Fulda and M. Manconi

6. New animal models of progressive neurodegeneration: tools for developing predictive diagnostics and identifying presymptomatic therapeutic targets; A. L. Marriott, D. A. Gill, C. A. Shaw, R. A. Tasker

7. Tau pathology: A selected view on the current status; I. Gozes

Part III

8. The Use of Biomarkers for Prediction and Prevention of Alzheimer's and Parkinson's Diseases; S. A. Mandel & A. D. Korczyn

9. Making clinical trials of Alzheimer's disease delay-of-onset a reality by use of a prognostic genetic biomarker; Iris Grossman

10. An update on CSF biomarkers of Parkinson's disease; Peter LeWitt, B Russell Huber, Jing Zhang

Part IV

11. Glaucomatous optic neuropathy: Risk assessment and potential targets for effective prevention and treatments tailored to the patient; O. Golubnitschaja, K. Yeghiazaryan, J. Flammer

Part V

12. Toward a personalized approach in amyotrophic lateral sclerosis: new developments in diagnosis, genetics, pathogenesis and therapies; B. Nefussy & V. E. Drory

13. Recent advances in ALS research: perspectives for personalized clinical application; C. Benkler, D. Offen, E. Melamed, T. Amit, S. Mandel, M. B.H. Youdim, O. Weinreb

Part VI

14. Exercise in Multiple Sclerosis - an Integral Component of Disease Management; A. Dцring, C. F. Pfueller, F. Pau, J. Dцrr

15. Bridging the Informatics Gap between Bench and Bedside: Implications to Neurodegenerative Diseases; A. Shabo (Shvo) & M. Scarpa

Part VII

16. Personalized Medicine In Rare Paediatric Neurometabolic Diseases; R. Tomanin, C. M. Bellettato, F. D'Avanzo, A. Zanetti, A. Ceci, D. Begley, M. Scarpa

All Around Suboptimal Health

Автор: Wang
Название: All Around Suboptimal Health
ISBN: 3031468902 ISBN-13(EAN): 9783031468902
Издательство: Springer
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Цена: 19514.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This volume demonstrates advanced strategies in biomedical sciences and healthcare focused on suboptimal health conditions in the framework of Predictive, Preventive and Personalised Medicine (3PM/PPPM). Potential benefits in healthcare systems and for society at large include but are not restricted to an improved life-quality of major populations and socio-economical groups, advanced professionalism of healthcare-givers and sustainable healthcare economy. Reactive medical services applied to healthcare resulted in epidemics of non-communicable diseases such as diabetes mellitus type 2 with currently about a half of billion patients registered worldwide. Far-reaching consequences are cascading co-morbidities with poor prognosis such as severe cardiovascular and neurological disorders, eye pathologies (e.g., proliferative diabetic retinopathy as the world leading cause of blindness) and several types of cancer, amongst others. Corresponding socio-economic burden is tremendous. The paradigm changes from reactive medicine to PPPM propagated by EPMA is, therefore, pivotal for advanced healthcare to improve the economy of medical services, life quality of populations and individual outcomes. To this end, individuals with suboptimal health condition comprise the target group for predictive diagnostics and cost-effective personalised treatments to protect affected individuals and sub-populations against health-to-disease transition, a window of opportunity for PPPM. This goal is of highest priority benefiting millions of people and societies at large.

Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future

Автор: Silvia Mandel
Название: Neurodegenerative Diseases: Integrative PPPM Approach as the Medicine of the Future
ISBN: 9400758650 ISBN-13(EAN): 9789400758650
Издательство: Springer
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Цена: 20733.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Individualized Medicine

Автор: Tobias Fischer; Martin Langanke; Paul Marschall; S
Название: Individualized Medicine
ISBN: 3319346989 ISBN-13(EAN): 9783319346984
Издательство: Springer
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Цена: 18237.00 р.
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Описание: In 2009 the University Medicine Greifswald launched the "Greifswald Approach to Individualized Medicine" (GANI_MED) to implement biomarker-based individualized diagnostic and therapeutic strategies in clinical settings.

Healthcare Overview

Автор: Costigliola V.
Название: Healthcare Overview
ISBN: 9400746016 ISBN-13(EAN): 9789400746015
Издательство: Springer
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Цена: 28497.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In healthcare, the realisation of an optimistic prognosis against pessimistic ones depends on current innovations in diagnostic and cost-effective treatment approaches being widely adopted in clinical practice. Utilisation of advanced early and predictive diagnostics, targeted prevention and personalised medical approaches could enable the elderly subpopulation to reach the 100-year age limit in good physical and mental health, as actively contributing members of society. This task requires intelligent political regulations and creation of new guidelines to advance current healthcare systems. In this book, we will collect contributions from several geopolitical regions of Europe, Asia and USA that provide expert opinion on healthcare organisation and outlook as well as economical aspects of personalised medicine.

New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM

Автор: Mahmood S. Mozaffari
Название: New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM
ISBN: 9400759703 ISBN-13(EAN): 9789400759701
Издательство: Springer
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Цена: 26216.00 р.
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Описание: This book is intended to provide up-to-date and emerging information in the field of diabetes mellitus with a focus on preventive, predictive and personalized medicine.

An Information Technology Framework for Predictive, Preventive and Personalised Medicine

Автор: Leonard Berliner; Heinz U. Lemke
Название: An Information Technology Framework for Predictive, Preventive and Personalised Medicine
ISBN: 3319384341 ISBN-13(EAN): 9783319384344
Издательство: Springer
Рейтинг:
Цена: 14635.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient -- functional status, liver function, degree of cirrhosis, and comorbidities;

Digital Health in Focus of Predictive, Preventive and Personalised Medicine

Автор: Chaari Lotfi
Название: Digital Health in Focus of Predictive, Preventive and Personalised Medicine
ISBN: 303049814X ISBN-13(EAN): 9783030498146
Издательство: Springer
Цена: 14635.00 р.
Наличие на складе: Нет в наличии.

Описание: This book is intended for periodontal residents and practicing periodontists who wish to incorporate the principles of moderate sedation into daily practice. Comprehensive airway management and rescue skills are then documented in detail so that the patient may be properly managed in the event that the sedation progresses beyond the intended level.

Healthcare Overview

Автор: Vincenzo Costigliola
Название: Healthcare Overview
ISBN: 9400799217 ISBN-13(EAN): 9789400799219
Издательство: Springer
Рейтинг:
Цена: 25075.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: In healthcare, the realisation of an optimistic prognosis against pessimistic ones depends on current innovations in diagnostic and cost-effective treatment approaches being widely adopted in clinical practice.

Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring

Автор: Peter B. Gahan
Название: Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring
ISBN: 9401791678 ISBN-13(EAN): 9789401791670
Издательство: Springer
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Цена: 19514.00 р.
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Описание: DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals. Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for treatment, treatment monitoring and clinical follow-up. In addition, the use in fetal medicine allows the early detection of fetal sex, Rh factor and aneuploid disorders as well as following both fetal and premature born infant development. This volume is intended as a primer for those who are interested in entering the field of circulating nucleic acids. The areas covered in this volume include: · Background and general biology of circulating nucleic acids · Methodology · Applications of circulating nucleic acids · Quality Assurance · Ethics


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