Описание: For nearly 40 years, the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, a publication of the American Society for Bone and Mineral Research (ASBMR), has been the leading comprehensive reference on bone and mineral health. In this fully revised 10th Edition, Dr. John P. Bilezikian and an expert editorial team of 34 global leaders and more than 300 contributing authors provide unsurpassed coverage of bone biology and bone diseases in a manner readily accessible to students, basic and clinical scientists, and practitioners.
Описание: Metabolic disorder caused by altered levels of metabolism resulting pathophysiological abnormalities often leads to childhood death. Several new developments on metabolic diseases research have been emerging. Gaucher disease is a lysosomal storage disorder caused by glucocerebrosidase gene mutations resulting glucocerebrosidase deficiency. Current studies show that the same gene mutations also contribute to the Parkinsons disease. Tetrahydrobiopterin (BH4) has been widely used in treating patients with Phenylketonuria over a decade. Recent studies reveal that patients treated with BH4 over one-year period showed reduced levels of serum B12, folate and iron intake and therefore patients under chronic BH4 treatment needed to be advised to have additional micronutrients along with BH4. Macrocephaly was used as one of the important features to diagnose Canavan disease. However, a recent study showing a child with aspartoacylase gene mutation developed microcephaly. Hence, Canavan disease phenotype can be either macrocephaly or microcephaly. These are a few examples of recent developments on metabolic diseases research. Therefore, this book was aimed to compose current developments on metabolic diseases research for the use by broad spectrum of experts including Physicians, Neuroscientists, Neurologists, Biomedical researchers, Biochemists, Molecular biologists, Basic Science Researchers and Medical Students.
Описание: This book presents a systematic and extensive understanding about metabolic alterations affecting multiple aspects of different neurodegenerative diseases (NDDs), such as Alzheimer’s, Parkinson’s, Huntington’s disease, SCAs, SBMA, DRPLA, ALS, Freidrich Ataxia etc. The book also illustrates cellular and molecular mechanisms behind the key neurodegenerative diseases and further expands on concept of unique and developing biomarkers associated with the onset and progression of NDDs. Additionally, it elaborates on the concept of latest imaging tools to monitor state of NDDs and accordingly develop therapeutic approaches entailing phytochemicals in the management of metabolic alterations associated with NDDs that ultimately suppresses course of devastating NDDs. The book aids to improve the overall understanding about the NDD and involvement of metabolic disorder as a major factor for indisposition of the disease. Therefore, suggesting that targetting metabolic variations by phytochemicals can combat NDD related symptoms for the betterment of impacted patients. While introducing cellular and molecular mechanisms and the treatment regimen under the umbrella of metabolism in several NDDs, the book covers major aspects of understanding the metabolic basis of NDDs, its implications, and treatment. This will inflate the readers' understanding about this particular area and guide those working in this domain, be it a researcher or clinicians,to choose or design effective therapeutic strategies to curb metabolic alterations linked with these disorders. This book will not only contribute towards improving the overall state of the challenged individuals but will also bring new hope towards improving the quality of lives of affected patients.
Автор: Avioli, Louis V. Название: Metabolic Bone Disease and Clinically Related Disorders ISBN: 0120687003 ISBN-13(EAN): 9780120687008 Издательство: Elsevier Science Рейтинг: Цена: 47161.00 р. Наличие на складе: Нет в наличии.
Описание: Review of orthopaedic oncology with case presentations illustrating how each tumor would be diagnosed and managed in a clinical setting.
Автор: Frederick Singer Название: Paget`s Disease of Bone ISBN: 1468423096 ISBN-13(EAN): 9781468423099 Издательство: Springer Рейтинг: Цена: 6097.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Paget`s disease is an old disease historically, but a new disease therapeutic- ally.
Автор: Coe Название: Disorders of Bone and Mineral Metab. ISBN: 0781717892 ISBN-13(EAN): 9780781717892 Издательство: Lippincott Williams & Wilkins Цена: 27944.00 р. Наличие на складе: Поставка под заказ.
Описание: The Second Edition of this comprehensive reference combines a strong scientific base with a clinical focus to address the principal disorders of bone and mineral metabolism, including osteoporosis, kidney stone formation, abnormal serum mineral levels, Paget's disease, and other conditio. The contributors examine normal bone structure and mineral metabolism throughout the life cycle, explain the mechanisms underlying each disorder, and provide succinct guidance on evaluation and management. This edition describes recently introduced drugs, thoroughly reviews powerful new treatments for osteoporosis and nephrolithiasis and also features completely rewritten chapters on stone formation. Over than 500 illustrations complement the text plus over 150 tables help readers find needed information at a glance.
The popular narrative of "globesity" posits that the adoption of Western diets is intensifying obesity and diabetes in the Global South and that disordered metabolisms are the embodied consequence of globalization and excess. In Metabolic Living Harris Solomon recasts these narratives by examining how people in Mumbai, India, experience the porosity between food, fat, the body, and the city. Solomon contends that obesity and diabetes pose a problem of absorption between body and environment. Drawing on ethnographic fieldwork carried out in Mumbai's home kitchens, metabolic disorder clinics, food companies, markets, and social services, he details the absorption of everything from snack foods and mangoes to insulin, stress, and pollutants. As these substances pass between the city and the body and blur the two domains, the onset and treatment of metabolic illness raise questions about who has the power to decide what goes into bodies and when food means life. Evoking metabolism as a condition of contemporary urban life and a vital political analytic, Solomon illuminates the lived predicaments of obesity and diabetes, and reorients our understanding of chronic illness in India and beyond.
The popular narrative of "globesity" posits that the adoption of Western diets is intensifying obesity and diabetes in the Global South and that disordered metabolisms are the embodied consequence of globalization and excess. In Metabolic Living Harris Solomon recasts these narratives by examining how people in Mumbai, India, experience the porosity between food, fat, the body, and the city. Solomon contends that obesity and diabetes pose a problem of absorption between body and environment. Drawing on ethnographic fieldwork carried out in Mumbai's home kitchens, metabolic disorder clinics, food companies, markets, and social services, he details the absorption of everything from snack foods and mangoes to insulin, stress, and pollutants. As these substances pass between the city and the body and blur the two domains, the onset and treatment of metabolic illness raise questions about who has the power to decide what goes into bodies and when food means life. Evoking metabolism as a condition of contemporary urban life and a vital political analytic, Solomon illuminates the lived predicaments of obesity and diabetes, and reorients our understanding of chronic illness in India and beyond.
Описание: Thyroid disorders affect many people worldwide, but luckily, they can often be avoided or cured quite simply through making some dietary changes. This book explains to you the different thyroid disorders out there, and the signs and symptoms of each.
Описание: Chronic disease states of aging should be viewed through the prism of metabolism and biophysical processes at all levels of physiological organization present in the human body. This book connects these insights to what causes them to go awry in the context of unhealthy human behaviors and aging, aiming to buttress scientific creativity.
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