Описание: In the anti-breast cancer antibody field the availability of molecular engineering approaches to humanize murine antibodies has induced intense interest in the creation of less immunogenic antibody forms that are now available for clinical testing.
Автор: Falk Nimmerjahn Название: Molecular and Cellular Mechanisms of Antibody Activity ISBN: 1489993606 ISBN-13(EAN): 9781489993601 Издательство: Springer Рейтинг: Цена: 19376.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent years have seen an exponential growth in knowledge about the molecular and cellular mechanisms of antibody activity. This book examines how these new results have dramatically changed our view of how antibodies function in vivo.
Автор: Borrebaeck, Carl A. K. Название: Antibody Engineering ISBN: 0195091507 ISBN-13(EAN): 9780195091502 Издательство: Oxford Academ Рейтинг: Цена: 15742.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This text has been designed to help researchers understand and develop designer antibodies. Its practical approach makes use of state-of-the-art technologies for the production of recombinant human or mouse monoclonal antibodies.
Автор: Uri Galili; Jos?-Luis Avila Название: ?–Gal and Anti–Gal ISBN: 1461371600 ISBN-13(EAN): 9781461371601 Издательство: Springer Рейтинг: Цена: 24392.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Pavol Ivanyi Название: MHC + X ISBN: 3642740286 ISBN-13(EAN): 9783642740282 Издательство: Springer Рейтинг: Цена: 13415.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Workshop-Symposium meeting held in Ommen/ Amsterdam, 7-9 October 1987
Автор: Patrick Chames Название: Antibody Engineering ISBN: 1493959441 ISBN-13(EAN): 9781493959440 Издательство: Springer Рейтинг: Цена: 21953.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: More than ever, antibodies are being recognized as a major drug modality in a variety of diseases, including cancer, autoimmune diseases, infectious diseases, or even neurodegenerative disorders. Over 30 therapeutic antibodies have been approved and novel molecules are entering clinical trials at an average rate of 50 per year and that is predicted to continue well into the future. Notwithstanding the many achievements already made in the field, there is still a lot of room for improvements for these molecules in terms of activity, and a plethora of approaches have been attempted to optimize these molecules. Antibody Engineering: Methods and Protocols, Second Edition was compiled to give complete and easy access to a variety of antibody engineering techniques, starting from the creation of antibody repertoires and efficient ways to select binders from these repertoires, to their production in various hosts, their detailed characterization using various well established techniques, and to the modification and optimization of these lead molecules in terms of binding activity, specificity, size, shape, and more. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Antibody Engineering: Methods and Protocols, Second Edition serves as an invaluable resource for both experts and those new to the field, and most of all as a source of inspiration for the creation of the antibodies of tomorrow.
Автор: Proetzel Название: Antibody Methods and Protocols ISBN: 1617799300 ISBN-13(EAN): 9781617799303 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The rapidly growing field of antibody research is the result of many advancing technologies allowing current developments to take advantage of molecular engineering to create tailor-made antibodies. Antibody Methods and Protocols attempts to provide insight into the generation of antibodies using in vitro and in vivo approaches, as well as technical aspects for screening, analysis, and modification of antibodies and antibody fragments. The detailed volume is focused on basic protocols for isolating antibodies and, at the same time, it selects a range of specific areas with the aim of providing guides for the overall process of antibody isolation and characterization as well as protocols for enhancing classical antibodies and antibody fragments. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and easy to use, Antibody Methods and Protocols provides a broad and useful background to support ongoing efforts by novices and experts alike and encourages the development of new imaginative approaches to this vital area of study.
Автор: Nair, Kodoth Prabhakaran Название: Antibody Glycosylation ISBN: 3030769119 ISBN-13(EAN): 9783030769116 Издательство: Springer Рейтинг: Цена: 16464.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Concise and well-structured chapters examine anatomy, physiology and pathophysiology, suprachoroidal haemorrhage, choroidal effusions and ocular hypotony management, imaging, suprachoroidal buckling for retinal detachment, drug delivery, suprachoroidal glaucoma devices, subretinal gene therapy and suprachoroidal retinal implant.
Автор: Tsumoto Название: Computer-Aided Antibody Design ISBN: 1071626086 ISBN-13(EAN): 9781071626085 Издательство: Springer Рейтинг: Цена: 17074.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume details state-of-the- art methods on computer-aided antibody design. Chapters guide readers through information on antibody sequences and structures, modeling antibody structures and dynamics, prediction and optimization of biological and biophysical properties of antibodies, prediction of antibody-antigen interactions, and computer-aided antibody affinity maturation and beyond. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Computer-Aided Antibody Design aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. Chapter 2 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Автор: Uri Galili; Jos?-Luis Avila Название: ?–Gal and Anti–Gal ISBN: 030646103X ISBN-13(EAN): 9780306461033 Издательство: Springer Рейтинг: Цена: 30370.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Anti-Gal is the most abundant antibody in humans, apes and Old World monkeys (monkeys of Asia and Africa). This title assembles the spectrum of information on the basic and clinical aspects of the natural anti-Gal antibody, the alpha-gal epitope and the enzyme producing it, alpha-1,3-galactosyltransferase.
Автор: Roland E. Kontermann; Stefan D?bel Название: Antibody Engineering Volume 2 ISBN: 3642011462 ISBN-13(EAN): 9783642011467 Издательство: Springer Рейтинг: Цена: 28051.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a toolbox of well-established basics and many exciting new techniques in antibody engineering, reflecting the latest hands-on work of key laboratories in this fast-moving field. The new edition is expanded to nearly double the number of protocols.
Автор: Robert Aitken (Ed.) Название: Antibody Phage Display ISBN: 1603273018 ISBN-13(EAN): 9781603273015 Издательство: Springer Рейтинг: Цена: 19514.00 р. Наличие на складе: Нет в наличии.
Описание: Phage display technology has revolutionized approaches to the analysis of biomedical problems, impacting the fields of immunology, cell biology, biotechnology, pharmacology, and drug discovery. This title provides a resource that guides readers in the design and execution of experiments based around antibody phage display.
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