Описание: Scientific advances over the past two decades have afforded unprecedented oppor- tunities to understand the structure and function of receptors, receptor-ligand interactions, and receptor signaling.
Автор: J.M. Saavedra; P.B.M.W.M. Timmermans Название: Angiotensin Receptors ISBN: 1461360498 ISBN-13(EAN): 9781461360490 Издательство: Springer Рейтинг: Цена: 6097.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: From molecular biology to clinical applications of selective receptor blockade, the present volume compiles the latest advances of this emerging field. Of particular importance is the attention given to the newly discovered AT2 receptors, and the physiology and pathophysiology of angiotensin receptor subtypes. The book will provide clinicians treating cardiovascular disease and hypertension with a clearer understanding of this therapeutically important and complicated hormone.
Автор: Amal K. Mukhopadhyay; Mohan K. Raizada Название: Tissue Renin-Angiotensin Systems ISBN: 1489909540 ISBN-13(EAN): 9781489909541 Издательство: Springer Рейтинг: Цена: 24392.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Highlighting the role local renin-angiotensin systems (RAS) play in pancreatic disease, this review presents the latest research advances in the field. These findings suggest both preventative measures and treatment for pancreatic disease.
Автор: Walmor C. DeMello; Edward D. Frohlich Название: Renin Angiotensin System and Cardiovascular Disease ISBN: 1617796387 ISBN-13(EAN): 9781617796388 Издательство: Springer Цена: 26711.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Systemic Versus Local Renin Angiotensin Systems: An Overview Walmor C De Mello, MD and Richard N Re, MD Clinical Importance of the Local Renin-Angiotensin aldosterone Systems Edward D. Frohlich, MD Renin, Prorenin And The (Pro)Renin Receptor Genevieve Nguyen and Aurelie Contrepas Local Renin-Angiotensin Systems in the Cardiovascular System Richard N Re, MD Renin-Angiotensin-Aldosterone System and Pathobiology of Hypertension Pierre Paradis, MD and Ernesto L. Schiffrin, MD At1 Receptors, Angiotensin Receptor Blockade and Clinical Hypertensive Disease Robert M. Carey, M.D., M.A.C. P Structural and Electrophysiologic Remodeling of the Failing Heart. On the Role of the Renin Angiotensin Aldosterone System Walmor C De Mello, MD Inhibiting the Renin Angiotensin Aldosterone System in Patients with Heart Failure and Myocardial Infarction Marc A. Pfeffer, M.D., Ph.D Left Ventricular Hypertrophy and Treatment With Renin-Angiotensin System Inhibition Edward D. Frohlich, MD and Javier Dнez, MD, PhD Angiotensin-(1-7), Angiotensin Converting Enzyme 2, and New Components of the Renin-Angiotensin System Aaron J. Trask, Jasmina Varagic, Sarfaraz Ahmad, Carlos M. Ferrario Kinin Receptors and ACE Inhibitors: an Interrelationship Ervin G. Erdцs, MD, Fulong Tan, PhD and Randal A. Skidgel, PhD Kinins and Cardiovascular Disease Oscar A. Carretero, M.D., Xiao-Ping Yang, MD, Nour-Eddine Rhaleb, PhD, FAHA CMS and Type 2 diabetes Mellitus: Bound together by the Renin-Angiotensin-Aldosterone System Deepashree Gupta, MD, Guido Lastra, MD, Camila Manrique, MD, James R Sowers, MD Renin Angiotensin Aldosterone System and CardiovascularDisease Swynghedauw Bernard, Milliez Paul, Messaoudi Smail, Benard Ludovic, Samuel Jane-Lise, Delcayre Claude Renin Angiotensin System and Atherosclerosis Changping Hu, Jawahar L. Mehta Renin Angiotensin System and Aging Leуn F. Ferder MD
Автор: Mancia Название: Angiotensin Ii Receptor Antagonists ISBN: 1841845795 ISBN-13(EAN): 9781841845791 Издательство: Taylor&Francis Рейтинг: Цена: 19140.00 р. Наличие на складе: Нет в наличии.
Описание: Preface... Table of Contents... Contributing Authors...
1. A Brief Introduction into the Renin-Angiotensin-Aldosterone System: New and Old Techniques Sean E. Thatcher
2. A Color Segmentation Based Method to Quantify Atherosclerotic Lesion Compositions with Immunostaining Congqing Wu, Alan Daugherty, and Hong Lu 3. Assessment of Protein Carbonylation and Protein Tyrosine Phosphatase (PTP) Oxidation in Vascular Smooth Muscle Cells (VSMCs) using Immunoblotting Approaches Sofia Tsiropoulou and Rhian M. Touyz 4. Methods for Studying the Role of RAAS in the Modulation of Vascular Repair-Relevant Functions of Stem/Progenitor Cells Yagna P.R. Jarajapu 5. Use of a Fluorescent Substrate to Measure ACE2 Activity in the Mouse Abdominal Aorta Yu Wang, Lisa A. Cassis, and Sean E. Thatcher 6. Measuring Blood Pressure using a Non-Invasive Tail Cuff Method in Mice Yu Wang, Sean E. Thatcher, and Lisa A. Cassis 7. Blood Pressure Monitoring using Radio Telemetry Method in Mice Yu Wang, Sean E. Thatcher, and Lisa A. Cassis 8. Characterization and Functional Phenotyping of Renal Immune Cells via Flow Cytometry Nathan P. Rudemiller and Steven D. Crowley 9. Assessment of the Renin-Angiotensin System in Cellular Organelle: New Arenas for Study in the Mitochondria Bryan A. Wilson and Mark C. Chappell 10. Comprehensive Assessments of Energy Balance in Mice Justin L. Grobe 11. In Vitro Assays to Determine Smooth Muscle Cell Hypertrophy, Protein Content, and Fibrosis Katherine J. Elliott and Satoru Eguchi 12. A New Mouse Model for Introduction of Aortic Aneurysm by Implantation of Deoxycorticosterone Acetate Pellets or Aldosterone Infusion in the Presence of High Salt Shu Liu, Ming C. Gong, and Zhenheng Guo 13. Fluorescence-Based Binding Assay for Screening Ligands of Angiotensin Receptors Maiia E. Bragina, Nikolaos Stergiopulos, and Rodrigo A. Fraga-Silva 14. A Primer to Angiotensin Peptide Isolation, Stability, and Analysis by Nano-Liquid Chromatography with Mass Detection Mariola Olkowicz, Stefan Chlopicki, and Ryszard T. Smolenski 15. Analysis of Angiotensin Metabolism in the Kidney using Mass Spectrometry Nadja Grobe and Khalid M. Elased
Автор: Naranjan S. Dhalla; Peter Zahradka; Ian M.C. Dixon Название: Angiotensin II Receptor Blockade Physiological and Clinical Implications ISBN: 1461376319 ISBN-13(EAN): 9781461376316 Издательство: Springer Рейтинг: Цена: 36589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The relationship between angiotensin II and hypertension was established in 1898 when angiotensin II was shown to modulate systemic blood pressure.
Автор: D. Ganten; M.P. Printz; M.I. Phillips; B.A. Sch?lk Название: The Renin Angiotensin System in the Brain ISBN: 3642464580 ISBN-13(EAN): 9783642464584 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The first publications on the presence of renin, angiotensino- gen and angiotensin-like material in brain tissue appeared about ten years ago. This coincided with the discovery of new biological actions of angiotensin in the brain and with the reinvestigation of already known central angiotensin effects. The possibility that angiotensin could be generated within the brain itself had therefore exciting implications. With the recent popularity of brain neuropeptides, interest in this area is even increasing. The discovery of renin-like activity as well as angiotensino- gen and angiotensin in the brain has led, admittedly by inductive inference, to the hypothesis of the existence of a complete endogenous renin-angiotensin system in the brain.1 For several years there was ardent discussion whether such a renin angiotensin system existed in the brain or not. Inductive inference always contains "an irrational element or a creative intuition".2In view of the biological relevance of a brain angiotensin system, deductive testing of the hypothesis was a worthwhile scientific project taken up by a number of investigators As a matter of principle it is not given to science, to reach either truth or falsity, scientific statements can only attain contmous degrees of probability whose unat- tamable upper and lower limits are truth or falsity. However, several of the early singular statements and results turned out to be reproducible and acceptable. The theory has thus so far passed its test and we have found no reason to discard it.
Автор: Naranjan S. Dhalla; Peter Zahradka; Ian M.C. Dixon Название: Angiotensin II Receptor Blockade Physiological and Clinical Implications ISBN: 0792381475 ISBN-13(EAN): 9780792381471 Издательство: Springer Рейтинг: Цена: 38908.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focuses on the developments in the molecular biology, cellular physiology and structure-function relationships of angiotensin II and its receptors. This volume covers the therapeutic uses for angiotensin receptor antagonists and considers their potential applications.
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