Описание: It chiefly focuses on the emerging targets of HDACs and their implications for various neurological disorders, while also discussing the drawbacks of current therapeutic strategies, the classification of HDAC inhibitors, and their promising effects in connection with specific neurological disorders.
Автор: Margueron Название: Histone Methyltransferases ISBN: 1071624806 ISBN-13(EAN): 9781071624807 Издательство: Springer Рейтинг: Цена: 18904.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides methods used to investigate histone methyltransferase function. Chapters guide readers through a comprehensive set of approaches that detail phylogenetic diversity, histone demethylase activities in vitro, generating chromatin substrates, auto-methylation, quantification of metabolites, protein purification, crystallization, X-ray structure, cryogenic electron microscopy, assessing genome-wide patterns, CUT&Tag in mouse embryonic tissues, chemical biology approaches, peptide SPOT arrays, nascent chromatin capture, ectopic protein tethering, computational models, and development of methyltransferase inhibitors. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Histone Methyltransferases: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Автор: Vipin Chandra Kalia Название: Biotechnological Applications of Quorum Sensing Inhibitors ISBN: 9811343020 ISBN-13(EAN): 9789811343025 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses the practical applications of quorum sensing inhibitors for both human and plant health. Quorum sensing inhibitors that disrupt microbial biofilms can be employed to treat bacterial infections. The book describes the various bioactive molecules that can serve as quorum sensing inhibitors to combat deadly bacterial infections, in addition to several synthetic quorum sensing inhibitors.Quorum sensing is the mechanism through which bacteria develop antibiotic resistance. Intended to provide a clearer understanding of the practical applications of quorum sensing inhibitors, the book details how the problem of antibiotic resistance can be countered through the intelligent application of quorum sensing inhibitors.
Автор: Kalia Название: Biotechnological Applications of Quorum Sensing Inhibitors ISBN: 9811090254 ISBN-13(EAN): 9789811090257 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book describes the various bioactive molecules that can serve as quorum sensing inhibitors to combat deadly bacterial infections, in addition to several synthetic quorum sensing inhibitors.Quorum sensing is the mechanism through which bacteria develop antibiotic resistance.
Автор: Fred E. Hahn Название: Modes and Mechanisms of Microbial Growth Inhibitors ISBN: 3642689485 ISBN-13(EAN): 9783642689482 Издательство: Springer Рейтинг: Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Further search for antibiotics has led to increasing frequency of rediscoveries and drasti- cally decreasing frequency of discoveries of new antibiotics.
Название: Viral proteases and their inhibitors ISBN: 0128097124 ISBN-13(EAN): 9780128097120 Издательство: Elsevier Science Рейтинг: Цена: 15831.00 р. Наличие на складе: Нет в наличии.
Описание: Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents.
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