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Histone Methyltransferases, Margueron


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Цена: 18904.00р.
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Автор: Margueron
Название:  Histone Methyltransferases
ISBN: 9781071624807
Издательство: Springer
Классификация:

ISBN-10: 1071624806
Обложка/Формат: Hardback
Страницы: 495
Вес: 1.16 кг.
Дата издания: 08.07.2022
Серия: Methods in Molecular Biology
Язык: English
Издание: 1st ed. 2022
Иллюстрации: 65 tables, color; 53 illustrations, color; 19 illustrations, black and white; xvii, 495 p. 72 illus., 53 illus. in color.
Размер: 254 x 178
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This volume provides methods used to investigate histone methyltransferase function. Chapters guide readers through a comprehensive set of approaches that detail phylogenetic diversity, histone demethylase activities in vitro, generating chromatin substrates, auto-methylation, quantification of metabolites, protein purification, crystallization, X-ray structure, cryogenic electron microscopy, assessing genome-wide patterns, CUT&Tag in mouse embryonic tissues, chemical biology approaches, peptide SPOT arrays, nascent chromatin capture, ectopic protein tethering, computational models, and development of methyltransferase inhibitors. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Histone Methyltransferases: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Дополнительное описание: Not all is SET for methylation: Evolution of eukaryotic protein methyltransferases.- Detection and quantification of histone methyltransferase activity in vitro.- In Vitro Histone Demethylase Assays.- Preparation and characterization of chromatin template



DNA Methyltransferases - Role and Function

Автор: Jeltsch
Название: DNA Methyltransferases - Role and Function
ISBN: 3031114531 ISBN-13(EAN): 9783031114533
Издательство: Springer
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Цена: 28051.00 р.
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Описание: This 2nd edition of the book on DNA methyltransferases has been comprehensively updated to reflect many novel research findings regarding the structure, function, and technology of these enzymes that have emerged over the past 6 years. Like the previous edition, this 2nd edition explains the biochemical properties of DNA methyltransferases, describing their structures, mechanisms and biological roles in bacteria, humans and plants. It also discusses the biological processes of reading DNA methylation and the mechanisms of DNA demethylation. This volume highlights the newest findings on DNA methyltransferase inhibitors and their use in cancer therapy as well as the latest epigenome editing systems based on these enzymes. Overall, this 2nd edition comprehensively summarizes the current state of research in the field of DNA methylation and DNA methyltransferase and is essential reading for early career and advanced researchers in this exciting field.

Histone Deacetylase Inhibitors As Cancer Therapeutics,116

Автор: Grant, Steven
Название: Histone Deacetylase Inhibitors As Cancer Therapeutics,116
ISBN: 0123943876 ISBN-13(EAN): 9780123943873
Издательство: Elsevier Science
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Цена: 17517.00 р.
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Описание: Provides information on the exciting and fast-moving field of cancer research.

Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders

Автор: Shabir Ahmad Ganai
Название: Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders
ISBN: 981138021X ISBN-13(EAN): 9789811380211
Издательство: Springer
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Цена: 12196.00 р.
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Описание: It chiefly focuses on the emerging targets of HDACs and their implications for various neurological disorders, while also discussing the drawbacks of current therapeutic strategies, the classification of HDAC inhibitors, and their promising effects in connection with specific neurological disorders.

Nucleosomes, Histones And Chromatin Part B,513

Автор: Wu, Carl
Название: Nucleosomes, Histones And Chromatin Part B,513
ISBN: 012391938X ISBN-13(EAN): 9780123919380
Издательство: Elsevier Science
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Цена: 23244.00 р.
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Описание: Part of the Methods in Enzymology series, this title covers Nucleosomes, Histones & Chromatin and has chapters on Dynamic mapping of histone-DNA interactions in nucleosomes by unzipping single molecules of DNA, Digital DNase technology, and Genome-wide Analysis of Chromatin Transition.

Nucleosomes, Histones And Chromatin Part A,512

Автор: Wu, Carl
Название: Nucleosomes, Histones And Chromatin Part A,512
ISBN: 0123919401 ISBN-13(EAN): 9780123919403
Издательство: Elsevier Science
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Цена: 23244.00 р.
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Описание: Part of the Methods in Enzymology series, this title covers Nucleosomes, Histones & Chromatin and has chapters on Methods applied to the High resolution identification of intra- and interchromosomal DNA interactions by 4C technology, and peptide arrays to interrogate the binding specificity of chromatin-binding proteins.


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