Описание: Why the Spike protein is relevant for COVID19 therapeutics
Whole genome mutation rates
Phylogenetic systems
Mechanism of immune escape: single nucleotide mutations, insertion/deletions, and recombination. Spike protein mutations detected in currently circulating strains.
SARS-CoV-2 variants
B.1.1.298
B.1.1.7 (alpha)
B.1.351 (beta)
B.1.1.28- and B.1.1.33-derived Brazilian variants (including gamma and zeta)
B.1.525 (eta)
B.1.526 (iota)
B.1.427/B.1.429 (epsilon)
B.1.617-derived variants (including kappa and delta)
B.1.617.1
Delta VOC
C.37 (lambda)
P.3 (theta)
Other variants under monitoring (VUM)
Which strain will finally become dominant?
SARS-CoV-2 variants characterization
Predicting the functional consequences of mutations
Efficacy of vaccines and monoclonal antibodies against SARS-CoV-2 variants
Selective pressures exerted by antibody-based therapeutics
Описание: Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure.
Описание: Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure.
Описание: As these begin to be deployed and administered across the globe, many now feel the virus will be brought under control and lives will eventually return to normal. This new volume will increase readers` understanding of the ongoing COVID-19 pandemic through a series of chapters that address these concerns.
Описание: This book reviews successes and (remaining) challenges in vaccine development for the selected Neglected Tropical Diseases (NTD) of Leprosy, Leishmaniasis, Meliodoisis and Tuberculosis, which are a continuous burden for millions of people in affected areas worldwide. Written by frontline researchers, the volume deep-dives into different vaccine strategies, provides biotechnological background information and also tackles animal models in NTD therapeutics research. By bringing together state-of-the-art expert knowledge, the book contributes to the aim of ultimately ending the epidemics of neglected tropical diseases, complying with UN Sustainable Development Goal 3, Health and Well-Being. The volume highlights the activities of the research network VALIDATE (VAccine deveLopment for complex Intracellular neglecteD pAThogEns), funded by the Medical Research Council in the UK. The four NTDs discussed in the book were selected as these are in the focus of VALIDATE’s research. The book targets scientists and clinicians working on NTDs, as well as all readers with a background in biomedicine and interest in vaccine development. This is an open access book.
Описание: This book reviews successes and (remaining) challenges in vaccine development for the selected Neglected Tropical Diseases (NTD) of Leprosy, Leishmaniasis, Meliodoisis and Tuberculosis, which are a continuous burden for millions of people in affected areas worldwide. Written by frontline researchers, the volume deep-dives into different vaccine strategies, provides biotechnological background information and also tackles animal models in NTD therapeutics research. By bringing together state-of-the-art expert knowledge, the book contributes to the aim of ultimately ending the epidemics of neglected tropical diseases, complying with UN Sustainable Development Goal 3, Health and Well-Being. The volume highlights the activities of the research network VALIDATE (VAccine deveLopment for complex Intracellular neglecteD pAThogEns), funded by the Medical Research Council in the UK. The four NTDs discussed in the book were selected as these are in the focus of VALIDATE’s research. The book targets scientists and clinicians working on NTDs, as well as all readers with a background in biomedicine and interest in vaccine development. This is an open access book.
Автор: Chu Название: SARS-CoV-2 ISBN: 1071621130 ISBN-13(EAN): 9781071621134 Издательство: Springer Рейтинг: Цена: 18904.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume provides the increasing number of SARS-CoV-2 researchers with a useful handbook covering multidisciplinary approaches on various aspects of SARS-CoV-2 research, brought together by leading laboratories across the globe. Topics covered include techniques in clinical and diagnostic virology, basic protocols in cell and virus culture, as well as bioinformatics and proteomics approaches in cellular response studies. This comprehensive collection also covers methods in immunology, animal models, antivirals and vaccine development strategies, as well as biorisk and mitigation measurements for SARS-CoV-2 research. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that is vital for success in the lab. Practical and timely, SARS-CoV-2: Methods and Protocols serves as an ideal guide for scientists investigating this prevalent and perilous RNA virus and the novel coronavirus disease that results from it.
Автор: Chu Название: SARS-CoV-2 ISBN: 1071621106 ISBN-13(EAN): 9781071621103 Издательство: Springer Рейтинг: Цена: 18904.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed volume provides the increasing number of SARS-CoV-2 researchers with a useful handbook covering multidisciplinary approaches on various aspects of SARS-CoV-2 research, brought together by leading laboratories across the globe. Topics covered include techniques in clinical and diagnostic virology, basic protocols in cell and virus culture, as well as bioinformatics and proteomics approaches in cellular response studies. This comprehensive collection also covers methods in immunology, animal models, antivirals and vaccine development strategies, as well as biorisk and mitigation measurements for SARS-CoV-2 research. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that is vital for success in the lab. Practical and timely, SARS-CoV-2: Methods and Protocols serves as an ideal guide for scientists investigating this prevalent and perilous RNA virus and the novel coronavirus disease that results from it.
Автор: W David Wick; Otto O Yang Название: War in the Body ISBN: 1489992553 ISBN-13(EAN): 9781489992550 Издательство: Springer Рейтинг: Цена: 25075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book surveys the wide evolutionary variations of HIV and the different, sometimes opposing theories which try to explain them. It compares ways that drugs anbd the immune system affect the virus`s evolution, and the implications for vaccine development.
Автор: W David Wick; Otto O Yang Название: War in the Body ISBN: 1461472938 ISBN-13(EAN): 9781461472933 Издательство: Springer Рейтинг: Цена: 26832.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book surveys the wide evolutionary variations of HIV and the different, sometimes opposing theories which try to explain them. It compares ways that drugs anbd the immune system affect the virus`s evolution, and the implications for vaccine development.
Автор: Edouard Kurstak; R.G. Marusyk; F.A. Murphy; M.H.V. Название: New Vaccines and Chemotherapy ISBN: 1475792700 ISBN-13(EAN): 9781475792706 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Viral Vaccines Joseph L. These reports, plus a third on Vaccine Supply and Innovation (1985a), should be required reading for all those in both the public and the private sector who have a responsibility or interest in vaccines for the prevention of human disease.
Автор: Sara Cohen; Avigdor Shafferman Название: Novel Strategies in the Design and Production of Vaccines ISBN: 148991384X ISBN-13(EAN): 9781489913845 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the 39th OHOLO Conference held in Eilat, Israel, May 7-11, 1995.
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