Bioinformatics in Microrna Research, Huang Jingshan, Borchert Glen M., Dou Dejing
Автор: Jingshan Huang; Glen M. Borchert; Dejing Dou; Jun Название: Bioinformatics in MicroRNA Research ISBN: 1493970445 ISBN-13(EAN): 9781493970445 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. MicroRNAs, Long Non-Coding RNAs, and Their Functions in Human Disease
Min Xue, Ying Zhuo, and Bin Shan
2. MicroRNA Expression: Protein Participants in MicroRNA Regulation
4. MicroRNAs: Biomarkers, Diagnostics, and Therapeutics
Weili Huang
5. Relational Databases and Biomedical Big Data
N.H. Nisansa D. de Silva
6. Semantic Technologies and Bio-Ontologies
Fernando Gutierrez
7. Genome-Wide Analysis of MicroRNA-Regulated Transcripts
David Chevalier and Glen M. Borchert
8. Computational Prediction of MicroRNA Target Genes, Target Prediction Databases, and Web Resources
Justin T. Roberts and Glen M. Borchert
9. Exploring MicroRNA:: Target Regulatory Interactions by Computing Technologies
Yue Hu, Wenjun Lan, and Daniel Miller
10. The Limitations of Existing Approaches in Improving MicroRNA Target Prediction Accuracy
Rasiah Loganantharaj and Thomas A. Randall
11. Genomic Regulation of MicroRNA Expression in Disease Development
Feng Liu
12. Next Generation Sequencing for MicroRNA Expression Profile
Yue Hu, Wenjun Lan, and Daniel Miller
13. Handling High-Dimension (High-Feature) MicroRNA Data
Yue Hu, Wenjun Lan, and Daniel Miller
14. Effective Removal of Noisy Data Via Batch Effect Processing
Ryan G. Benton
15. Logical Reasoning (Inferencing) on MicroRNA Data
Jingsong Wang
16. Machine Learning Techniques in Exploring MicroRNA Gene Discovery, Targets, and Functions
Sumi Singh, Ryan G. Benton, Anurag Singh, and Anshuman Singh
17. Involvement of MicroRNAs in Diabetes and Its Complications
Bin Wu and Daniel Miller
18. MicroRNA Regulatory Networks as Biomarkers in Obesity: The Emerging Role
Lihua Zhang, Daniel Miller, Qiuping Yang, and Bin Wu
19. Expression of MicroRNAs in Thyroid Carcinoma
Gaohong Zhu, Lijun Xie, and Daniel Miller
Автор: Paul Название: Microrna perspectives in health an ISBN: 1138054836 ISBN-13(EAN): 9781138054837 Издательство: Taylor&Francis Рейтинг: Цена: 19140.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book explores the role of miRNA as therapeutic agents, the progress made in this direction and the problems that need to be addressed for miRNA based therapies to become successful. It also discusses the basic biology of miRNA sythesis, regulation, and their role in disease biology.
Автор: Malik Yousef; Jens Allmer Название: miRNomics: MicroRNA Biology and Computational Analysis ISBN: 1627037470 ISBN-13(EAN): 9781627037471 Издательство: Springer Рейтинг: Цена: 13415.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In miRNomics: MicroRNA Biology and Computational Analysis, expert researchers in the field present an overview of the current state of the art and aim to put the respective areas of research into a larger perspective.
Автор: Ulf Schmitz; Olaf Wolkenhauer; Julio Vera Название: MicroRNA Cancer Regulation ISBN: 9402400796 ISBN-13(EAN): 9789402400793 Издательство: Springer Рейтинг: Цена: 20516.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses the role of microRNAs in the formation and progression of solid tumors. The main focus is on computational methods and applications, together with experimental techniques used to approach all aspects of microRNA regulation in cancer.
Автор: Karl L. Mettinger; Pranela Rameshwar; Vinod Kumar Название: Exosomes, Stem Cells and MicroRNA ISBN: 3030089991 ISBN-13(EAN): 9783030089993 Издательство: Springer Рейтинг: Цена: 19514.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume provides insight into the pivotal roles of stem cells, exosomes and other microvesicles in biofunction and molecular mechanisms and their therapeutic potential in translational nanomedicine. It further highlights evidence from recent studies as to how stem cell derived exosomes and microRNAs may restore and maintain tissue homeostasis, enable cells to recover critical cellular functions and begin repair regeneration. These early studies in animal models of aging also show evidence of improved immune, cardiovascular and cognitive functions as well as improved health span and life span. The use of exosomes from body fluids to define specific biomarkers for various tumors may also clear the path to patient-targeted treatments by developing exosome-derived microRNA based cancer therapeutics. It is essential reading for graduate students, research fellow and biomedical researchers in academia or the pharmaceutical or biotech industries.
Автор: Rani Название: MicroRNA Profiling ISBN: 1493965220 ISBN-13(EAN): 9781493965229 Издательство: Springer Рейтинг: Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume includes comprehensive descriptions of miRNA biogenesis and their role in the development and progression of various human diseases. The first few chapters of MicroRNA Profiling: Methods and Protocols discuss the effects of over-expressing and repressing of a target miRNA and their effects on cell viability and proliferation. The next few chapters explore the protocols for total RNA isolation from cells and cell-derived product including formalin fixed paraffin embedded tissue and plant tissue. The last few chapters discuss isolation and characterization of exosomes from medium conditioned by cell lines, serum, and plasma specimens. This book also includes discussions of several software tools, such as miRandola, PicTar, DIANA, and miRWalk. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, MicroRNA Profiling: Methods and Protocols is a valuable resource for anyone interested in the field of Micro RNAs.
Автор: Ion Mandoiu; Giri Narasimhan; Yanqing Zhang Название: Bioinformatics Research and Applications ISBN: 3642015506 ISBN-13(EAN): 9783642015502 Издательство: Springer Рейтинг: Цена: 9146.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Constitutes the refereed proceedings of the 5th International Symposium on Bioinformatics Research and Applications, ISBRA 2009, held in Fort Lauderdale, FL, USA, in May 2009. This title covers a wide range of topics, including clustering and classification, gene expression analysis, gene networks, genome analysis, and protein domain interactions.
Описание: This book constitutes the proceedings of the 16th International Symposium on Bioinformatics Research and Applications, ISBRA 2020, held in Moscow, Russia, in December 2020. The 23 full papers and 18 short papers presented in this book were carefully reviewed and selected from 131 submissions.
Автор: Rune Matthiesen Название: Bioinformatics Methods in Clinical Research ISBN: 1617796700 ISBN-13(EAN): 9781617796708 Издательство: Springer Рейтинг: Цена: 17684.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Covering the latest developments in clinical omics, this volume details the algorithms currently used in publicly available software tools. It looks at statistics, algorithms, automated data retrieval, and experimental consideration in the various omics areas.
Описание: This book discusses topics related to bioinformatics, statistics, and machine learning, presenting the latest research in various areas of bioinformatics.
Автор: Wadhwa, Gulshan. Название: Current trends in bioinformatics : ISBN: 981107481X ISBN-13(EAN): 9789811074813 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Нет в наличии.
Описание: This book highlights the latest breakthrough developments in bioinformatics. It presents a series of timely, in-depth reviews, drug clinical trial studies, biodiversity informatics and thematic issues. In addition, it includes insightful reviews on advances in computational molecular/structural biology, which address areas such as computing in biomedicine and genomics, computational proteomics and systems biology, and metabolic pathway engineering. Innovations in these fields have direct impacts on key issues related to healthcare, medicine, genetic disorders, the development of agricultural products, renewable energy, and environmental protection. Written by respected leaders in the field and covering a wide range of topics involving the integration of biology with computer and information science, the book offers an ideal basis for teaching at the undergraduate and graduate levels. It can also be used for self-instruction by research investigators interested in applying bioinformatics-based analytical methods and information technologists working with academic and industrial laboratories.
Автор: J. Rigden, Daniel (Ed.) Название: From Protein Structure to Function with Bioinformatics ISBN: 9402414827 ISBN-13(EAN): 9789402414820 Издательство: Springer Рейтинг: Цена: 36589.00 р. Наличие на складе: Нет в наличии.
Описание: This book is about protein structural bioinformatics and how it can help understand and predict protein function. It covers structure-based methods that can assign and explain protein function based on overall folds, characteristics of protein surfaces, occurrence of small 3D motifs, protein-protein interactions and on dynamic properties. Such methods help extract maximum value from new experimental structures, but can often be applied to protein models. The book also, therefore, provides comprehensive coverage of methods for predicting or inferring protein structure, covering all structural classes from globular proteins and their membrane-resident counterparts to amyloid structures and intrinsically disordered proteins. The book is split into two broad sections, the first covering methods to generate or infer protein structure, the second dealing with structure-based function annotation. Each chapter is written by world experts in the field. The first section covers methods ranging from traditional homology modelling and fold recognition to fragment-based ab initio methods, and includes a chapter, new for the second edition, on structure prediction using evolutionary covariance. Membrane proteins and intrinsically disordered proteins are each assigned chapters, while two new chapters deal with amyloid structures and means to predict modes of protein-protein interaction. The second section includes chapters covering functional diversity within protein folds and means to assign function based on surface properties and recurring motifs. Further chapters cover the key roles of protein dynamics in protein function and use of automated servers for function inference. The book concludes with two chapters covering case studies of structure prediction, based respectively on crystal structures and protein models, providing numerous examples of real-world usage of the methods mentioned previously. This book is targeted at postgraduate students and academic researchers. It is most obviously of interest to protein bioinformaticians and structural biologists, but should also serve as a guide to biologists more broadly by highlighting the insights that structural bioinformatics can provide into proteins of their interest.
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