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The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation, Rossetti Carlo, Peri Francesco


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Автор: Rossetti Carlo, Peri Francesco
Название:  The Role of Toll-Like Receptor 4 in Infectious and Non Infectious Inflammation
ISBN: 9783030563189
Издательство: Springer
Классификация:




ISBN-10: 3030563189
Обложка/Формат: Hardcover
Страницы: 174
Вес: 0.44 кг.
Дата издания: 16.12.2020
Серия: Progress in inflammation research
Язык: English
Издание: 1st ed. 2021
Иллюстрации: 10 illustrations, color; 9 illustrations, black and white; xi, 174 p. 19 illus., 10 illus. in color.
Размер: 23.39 x 15.60 x 1.27 cm
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: TLR4 is one of the most important innate immunity receptors, its function mainly consisting in the activation of inflammatory pathways in response to stimulation by Pathogen-Associated Molecular Patterns (PAMPs) and Damage Associated Molecular Pattern molecules (DAMPs). This volume critically reviews the different types of TLR4 activators and inhibitors, discusses the role of molecular aggregates in agonism/antagonism as well as the pivotal role of the CD14 receptor in the modulation of TLR4 signal and the molecular details and actors of the intracellular cascade. The book presents the role of TLR4 in several pathologies, such as sepsis and septic shock caused by receptor activation by gram-negative bacterial lipopolysaccharide (LPS), in neurodegenerative and neurological diseases such as Parkinson and Alzheimer’s diseases, and Amyotrophic Lateral Sclerosis (ALS). It reviews the role of TLR4 in neural stem cell-mediated neurogenesis and neuroinflammation and in Human Induced Pluripotent Stem Cells and Cerebral Organoids and discusses the emerging role of micro-RNA (miRNA) regulation by TLR4.
Дополнительное описание: Chapter 1. Chemically synthesized TLR4 ligands, their immunological functions and potential as vaccine adjuvant.- Chapter 2. Intracellular TLR4 signaling.- Chapter 3. TLR4 Ligands: Single Molecules and Aggregates.- Chapter 4. CD14: not just chaperone, but



Mims` Pathogenesis of Infectious Disease, 6 ed.

Автор: Anthony A. Nash, Robert G. Dalziel, J.Ross Fitzger
Название: Mims` Pathogenesis of Infectious Disease, 6 ed.
ISBN: 0123971888 ISBN-13(EAN): 9780123971883
Издательство: Elsevier Science
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Цена: 5422.00 р. 7746.00 -30%
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Описание: Mims' Pathogenesis of Infectious Disease is the landmark book in the field of infectious disease. The new, revised edition of this work provides a comprehensive, up-to-date description of the mechanisms of microbial infection and the pathogenesis of infectious disease. Presented in a clear, accessible style, it deals in an integrated manner with the spectrum of microorganisms, describing the factors common to all infectious diseases. Molecular biology, pathology, and immunology are brought together to explain the mechanisms for spread, immune response, and recovery.

  • Describes the origin and molecular biology of pandemic influenza, HIV1, and HIV2 as well as the recent work on papillomaviruses, herpesviruses, BSE, and variant CJD
  • Contains the latest data on tuberculosis, microbial evasion of immune defenses, and the spread of antibiotic resistance genes among bacteria
  • Provides an update on vaccines, prions, immune evasion, and microbial ligands and receptors
  • Gives an up-to-date picture of the global burden of infectious diseases
Toll-Like Receptor Family Members and Their Ligands

Автор: Bruce Beutler; Hermann Wagner
Название: Toll-Like Receptor Family Members and Their Ligands
ISBN: 3642639755 ISBN-13(EAN): 9783642639753
Издательство: Springer
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Цена: 14818.00 р.
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Описание: On occasion, the innate immune system is referred to as the "primitive" immune system. On the contrary, the innate immune system has had time to achieve a level of refinement that is nothing short of dazzling, and a modicum of respect is at long last due.

Toll-Like Receptors: Practice and Methods

Автор: McCoy Claire
Название: Toll-Like Receptors: Practice and Methods
ISBN: 1493980238 ISBN-13(EAN): 9781493980239
Издательство: Springer
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Цена: 13415.00 р.
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Описание: This second edition volume expands on the first edition with new developments on Toll-Like Receptors (TLRs) controlling events such as cross-priming of associated pattern recognition receptors, post-transcriptional regulation, interaction with other cellular and biologic systems, and cancer progression.

Toll-Like Receptors

Автор: Claire McCoy
Название: Toll-Like Receptors
ISBN: 1493933337 ISBN-13(EAN): 9781493933334
Издательство: Springer
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Цена: 18294.00 р.
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Описание: This second edition volume expands on the first edition with new developments on Toll-Like Receptors (TLRs) controlling events such as cross-priming of associated pattern recognition receptors, post-transcriptional regulation, interaction with other cellular and biologic systems, and cancer progression.

Toll-like Receptors: Roles in Infection and Neuropathology

Автор: Tammy Kielian
Название: Toll-like Receptors: Roles in Infection and Neuropathology
ISBN: 3642269117 ISBN-13(EAN): 9783642269110
Издательство: Springer
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Цена: 24392.00 р.
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Описание: This book highlights traditional roles for TLRs in infectious diseases of the CNS. It also discusses recently emerging roles for TLRs in non-infectious neurodegenerative diseases and the challenges faced in these models with identifying endogenous ligands.

Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease

Автор: Deric L. Wheeler; Yosef Yarden
Название: Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease
ISBN: 1493920529 ISBN-13(EAN): 9781493920525
Издательство: Springer
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Цена: 19377.00 р.
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Описание: Receptor Tyrosine Kinase: Structure, Functions and Role in Human Disease, for the first time, systematically covers the shared structural and functional features of the RTK family.

Receptor-like Kinases in Plants

Автор: Frans Tax; Birgit Kemmerling
Название: Receptor-like Kinases in Plants
ISBN: 3642447988 ISBN-13(EAN): 9783642447983
Издательство: Springer
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Цена: 27931.00 р.
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Описание: Revealed by sequencing projects, receptor kinases are the largest group of primary signal transducers in plants. Their abundance hints at an immense network that we have just begun to reveal. This volume focuses on their role, signaling paths, and regulation.

Principles of Receptor Physiology

Автор: Werner R. Loewenstein
Название: Principles of Receptor Physiology
ISBN: 3642650651 ISBN-13(EAN): 9783642650659
Издательство: Springer
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Цена: 15855.00 р.
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Описание: Why should there be a handbook of sensory physiology, and if so, why now' The editors have asked this question, marshalled all of the arguments that seemed to speak against their project, and then discovered that most of these arguments really spoke in favor of it: there seemed to be no doubt that the attempt should be made and that it should be made now. No complete overview of sensory physiology has been attempted since Bethe's "Handbuch der normalen und pathologischen Physiologie", nearly forty years ago. Since then, the field has evolved with unforeseen rapidity. Although electric probing of single peripheral nerve fibers was begun by ADRIAN and ZOTTERMAN as early as 1926, in the somatosensory system, and extended to single optic nerve fibers by HARTLINE in 1932, the real upsurge of such single-unit studies has only come during the last two decades. Single-cell electrophysiology has now been applied to all sensory modalities and on almost every conceivable phylogenetic level. It has begun to clarify peripheral receptor action and is adding to our. understanding of the central processing of sensory information. In parallel with these developments, there have been fundamental studies of the physics and chemistry of the receptors themselves: these studies are leading to insights into the mechanisms of energy transduction and nerve impulse initiation.

Semaphorins: Receptor and Intracellular Signaling Mechanisms

Автор: Gerard Pasterkamp
Название: Semaphorins: Receptor and Intracellular Signaling Mechanisms
ISBN: 1441924272 ISBN-13(EAN): 9781441924278
Издательство: Springer
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Цена: 27931.00 р.
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Описание: This book details our progress in understanding the receptor and intracellular signaling mechanisms utilized by semaphorins. The comprehensive overview of semaphorin biology and signaling presented in this book allows one to compare semaphorin functions between different biological systems.


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