Mosaicism in Human Skin, Happle

Автор: Happle Rudolf
Название: Mosaicism in Human Skin
ISBN: 3642387640 ISBN-13(EAN): 9783642387647
Издательство: Springer
Рейтинг:
Цена: 20123.00 р.
Наличие на складе: Нет в наличии.

Описание: This book presents an overview on the strikingly manifold patterns and peculiarities of mosaic skin disorders. It will help dermatologists understand the underlying molecular mechanisms of skin disorders in order to further improve the treatment outcome.

Автор: Happle
Название: Mosaicism in Human Skin
ISBN: 3030899365 ISBN-13(EAN): 9783030899363
Издательство: Springer
Рейтинг:
Цена: 13415.00 р.
Наличие на складе: Нет в наличии.

Описание: This second edition offers a fully revised and updated work on a rapidly growing field of knowledge, and was prepared by two experts whose goal was to explain the molecular basis of mosaic skin disorders in a language that is accessible for practicing physicians and medical students alike. It presents a timely and comprehensive overview of the strikingly manifold patterns and peculiarities of mosaic skin disorders in a straightforward, reader-friendly way that will help physicians to further improve genetic counseling and treatment outcomes. The first two parts of the book are devoted to the mechanisms and patterns of cutaneous mosaicism, and include an explanation of genomic and epigenetic mosaicism and a description of the archetypical segmental patterns including the lines of Blaschko and the flag-like, phylloid and lateralization pattern, the non-segmental pattern of large congenital melanocytic nevi, and the sash-like arrangement as noted in a particular type of cutis tricolor. The concept of lethal mutations surviving as mosaics has now been confirmed by molecular analysis in many sporadically occurring phenotypes. The difference between monoallelic and biallelic traits has deepened our understanding of hereditary mosaics, especially of multiple benign skin tumors. Moreover, recognition of the fundamental difference between the simple segmental and the superimposed types of mosaicism is important for the purpose of genetic counseling. In the third part, the various mosaic skin disorders are examined in depth, including nevi, didymotic disorders, other binary genodermatoses, mosaic manifestations of autosomal skin disorders, and nevoid skin disorders such as phenotypes reflecting functional X-chromosome mosaicism or a superimposed mosaic manifestation of common skin diseases with a polygenic background. Reader-friendly and clearly structured, Mosaicism in Human Skin will appeal to both experienced dermatologists and residents in training, as well as to medical geneticists and pediatricians.

Автор: Panfilov
Название: Aesthetic Surgery of the Facial Mosaic
ISBN: 3540331603 ISBN-13(EAN): 9783540331605
Издательство: Springer
Цена: 52324.00 р.
Наличие на складе: Нет в наличии.

Описание: Over the last few decades the outcome of facial plastic surgery (facelifts) has improved dramatically and has also had an increasing impact on the quality of life for the aging population. Younger patients have also recently expressed interest in individual beautification of their features. This authoritative reference book assembles the experience of an international faculty of authors, each of whom has performed several thousand facelifts, i.e. procedures to rejuvenate and harmonize the human face. All procedures in this regard are covered and the text is accompanied by extensive artwork and photographs. The authors share their experience, including tips and tricks, as well as ways to avoid complications and pitfalls. Special emphasis is given to the concept of looking at the face as a mosaic, i.e. treating its individual parts in a harmonic way and maintaining mimic units. Combining different methods, it is possible to improve the overall outcome and diminish the aggressiveness of singular procedures, which results in fewer risks and fewer complications. The book is aimed at plastic surgeons beginning to perform facial plastic surgery as well as experienced surgeons, who will benefit from the vast and profound experience of the contributing authors. A kaleidoscope of 363 important aspects, tips and tricks in facial plastic surgery rounds up the presentation. The included DVD further enhances the practical value of the book with videos of procedures performed by the editor.