Автор: Alexander Heifetz Название: Computational Methods for GPCR Drug Discovery ISBN: 1493974645 ISBN-13(EAN): 9781493974641 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume looks at modern computational strategies and techniques used in GPCR drug discovery including structure and ligand-based approaches and cheminformatics.
Автор: Riccardo Baron Название: Computational Drug Discovery and Design ISBN: 1493962272 ISBN-13(EAN): 9781493962273 Издательство: Springer Рейтинг: Цена: 18904.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Due to the rapid and steady growth of available low-cost computer power, the use of computers for discovering and designing new drugs is becoming a central topic in modern molecular biology and medicinal chemistry. In Computational Drug Discovery and Design: Methods and Protocols expert researchers in the field provide key techniques to investigate biomedical applications for drug developments based on computational chemistry. These include methods and techniques from binding sites prediction to the accurate inclusion of solvent and entropic effects, from high-throughput screening of large compound databases to the expanding area of protein-protein inhibition, toward quantitative free-energy approaches in ensemble-based drug design using distributed computing. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, reference to software and open source analysis tools, step-by-step, readily reproducible computational protocols, and key tips on troubleshooting and avoiding known pitfalls. Thorough and intuitive, Computational Drug Discovery and Design: Methods and Protocols aids scientists in the continuing study of state-of-the-art concepts and computer-based methodologies.
Автор: Kaushik Название: Bioinformatics Techniques for Drug Discovery ISBN: 3319757318 ISBN-13(EAN): 9783319757315 Издательство: Springer Рейтинг: Цена: 6097.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The application of bioinformatics approaches in drug design involves an interdisciplinary array of sophisticated techniques and software tools to elucidate hidden or complex biological data.
Автор: Gore Название: Computational Drug Discovery and Design ISBN: 1493977555 ISBN-13(EAN): 9781493977550 Издательство: Springer Рейтинг: Цена: 10976.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume details methods and techniques for identification of drug targets, binding sites prediction, high-throughput virtual screening,and prediction of pharmacokinetic properties using computer based methodologies. Chapters guide readers through techniques of the available computational tools, developing prediction models for drug target prediction and de novo design of ligands, structure based drug designing, fragment-based drug designing, molecular docking, and scoring functions for assessing protein-ligand docking protocols. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Computational Drug Discovery and Design aims to provide protocols for the use of bioinformatics tools in drug discovery and design.
Автор: Loging William T. Название: Bioinformatics and Computational Biology in Drug Discovery a ISBN: 1108461158 ISBN-13(EAN): 9781108461153 Издательство: Cambridge Academ Рейтинг: Цена: 5702.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Providing a comprehensive overview of the drug discovery and development pipeline, this book focuses on the integral role that computational biology methods play in this process. Covering technological advances and their relation to drug developmental processes, readers are exposed to new methods of discovery utilising the available technology.
Автор: MacCuish, John David , MacCuish, Norah E. Название: Clustering in Bioinformatics and Drug Discovery ISBN: 1138374237 ISBN-13(EAN): 9781138374232 Издательство: Taylor&Francis Рейтинг: Цена: 10104.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
With a DVD of color figures, Clustering in Bioinformatics and Drug Discovery provides an expert guide on extracting the most pertinent information from pharmaceutical and biomedical data. It offers a concise overview of common and recent clustering methods used in bioinformatics and drug discovery.
Setting the stage for subsequent material, the first three chapters of the book introduce statistical learning theory, exploratory data analysis, clustering algorithms, different types of data, graph theory, and various clustering forms. In the following chapters on partitional, cluster sampling, and hierarchical algorithms, the book provides readers with enough detail to obtain a basic understanding of cluster analysis for bioinformatics and drug discovery. The remaining chapters cover more advanced methods, such as hybrid and parallel algorithms, as well as details related to specific types of data, including asymmetry, ambiguity, validation measures, and visualization.
This book explores the application of cluster analysis in the areas of bioinformatics and cheminformatics as they relate to drug discovery. Clarifying the use and misuse of clustering methods, it helps readers understand the relative merits of these methods and evaluate results so that useful hypotheses can be developed and tested.
Автор: Saxena Anil Kumar Название: Biophysical and Computational Tools in Drug Discovery ISBN: 3030852806 ISBN-13(EAN): 9783030852801 Издательство: Springer Цена: 36589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews recent physicochemical and biophysical techniques applied in drug discovery research, and it outlines the latest advances in computational drug design.
Автор: Moini, Jahangir (Retired Professor, Science and Health Department, Eastern Florida State College, FL, USA) Oyindamola, Akinso (Assistant Professor of Название: Computational Approaches in Drug Discovery, Development and Systems Pharmacology ISBN: 0323991378 ISBN-13(EAN): 9780323991377 Издательство: Elsevier Science Рейтинг: Цена: 22738.00 р. Наличие на складе: Нет в наличии.
Описание: Featuring an easy-to-learn and easy-to-use reference system acclaimed for more than five generations, the Thompson Chain-Reference Bible enables you to search the breadth of Scripture`s teachings on thousands of topics. Ideal for personal study and sermon preparation, it`s now easier to read with the NKJV Comfort Print typeface.
Описание: Escape is the story of Eileen, the grieving mother of a daughter who was born with a heart defect. Now, separated from her husband, she is whisked away to vacation on a remote Nova Scotia island with her closest friends. When Eileen and her faithful dog, Ellie, arrive at Brier Island, she is completely consumed with grief. Her thoughts are focused only on the loss of her daughter. As Eileen and Ellie explore the island, she meets the often eccentric yet very accepting locals. The islanders welcome her with open arms showing her a different way of life than she has ever known. East Coast kitchen parties and the strong sense of community help Eileen
Автор: Bultinck, Patrick Название: Computational Medicinal Chemistry for Drug Discovery ISBN: 0824747747 ISBN-13(EAN): 9780824747749 Издательство: Taylor&Francis Рейтинг: Цена: 46702.00 р. Наличие на складе: Нет в наличии.
Автор: MacCuish, John David Название: Clustering in Bioinformatics and Drug Discovery ISBN: 1439816786 ISBN-13(EAN): 9781439816783 Издательство: Taylor&Francis Рейтинг: Цена: 15310.00 р. Наличие на складе: Нет в наличии.
