Описание: Enthusiastically acclaimed by medical students and faculty worldwide, this text is specifically designed to prepare students for their first encounters with patients with cardiovascular disease. Thoroughly revised by internationally recognized Harvard Medical School faculty and a team of select cardiology fellows and internal medicine residents, this seventh edition equips students with a clear, complete, and clinically relevant understanding of cardiovascular pathophysiology, setting a strong foundation for patient diagnosis and management. New seventh edition highlights:Review questions and answers in each chapter prepare students for course and board exams.
New contributors include cardiology fellows and internal medicine residents, who worked closely with faculty to extend coverage of clinically pertinent issues for medical students. Updated content reflects the latest understanding of mechanisms of cardiac disease and technological advances. Classic student-friendly features:Full-color illustrations help readers visualize and quickly grasp key concepts.
Medical imaging and color clinical photographs show real-world examples of many clinically relevant cardiovascular conditions. Introductory chapter outlines and end-of-chapter summaries provide organized, quick review of core information. Bonus online study tools:Animations help support understanding of complex, dynamic disease processes.
Interactive question bank reinforces learning and improves retention.
Автор: Peter D Turnpenny, Sian Ellard, Ruth Cleaver Название: Emery`s Elements of Medical Genetics and Genomics, 16e ISBN: 0702079669 ISBN-13(EAN): 9780702079665 Издательство: Elsevier Science Рейтинг: Цена: 7241.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Long recognized as a leading textbook in this fast-moving field, Emery's Elements of Medical Genetics and Genomics offers current, complete information with a strong basis in practical clinical genetics and genomics for medical school and beyond. The 16th Edition of this award-winning text has been thoroughly updated throughout and includes case-based and multiple-choice questions, end-of-chapter summaries, an extensive glossary, and convenient online access, making it an ideal choice for all medical undergraduates as well as postgraduates seeking to improve their understanding and knowledge.
Includes new case-based studies with questions and answers throughout, in addition to multiple-choice self-assessment questions for study and review.
Covers key topics such as pharmacogenetics, personalized medicine, prenatal testing, reproductive genetics, and ethical and legal issues in medical genetics.
Divides the text into three easy-to-use sections: The Scientific Basis of Human Genetics, Genetics in Medicine and Genomic Medicine, and Clinical Genetics, Counseling and Ethics
Features full-color illustrations and other images that help readers visualize the appearance of genetic disorders and assist with the understanding of complex genetic structures.
Contains learning features such as summary boxes, an extensive glossary of terms, online hyperlinks to important genetics websites and clinical databases, and more.
Presents the extensive knowledge and experience of distinguished editors Peter D. Turnpenny and Sian Ellard, as well as new editor Ruth Cleaver.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Автор: Anthony J.F. Griffiths, John Doebley, Catherine Pe Название: An Introduction to Genetic Analysis ISBN: 1319114776 ISBN-13(EAN): 9781319114770 Издательство: Macmillan Learning Рейтинг: Цена: 14452.00 р. Наличие на складе: Нет в наличии.
Описание: The evolution of a classicThe new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level.
Автор: Lupski Название: Genomic Disorders. 2006 ISBN: 1588295591 ISBN-13(EAN): 9781588295590 Издательство: Springer Рейтинг: Цена: 9391.00 р. 13415.00-30% Наличие на складе: Есть (1 шт.) Описание: A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
Автор: Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra Название: Post-genomic Approaches in Drug and Vaccine Development ISBN: 8793102844 ISBN-13(EAN): 9788793102842 Издательство: Taylor&Francis Рейтинг: Цена: 13320.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Over the past decade, genome sequencing projects and associated efforts have facilitated the discovery of several novel disease targets and the approval of several innovative drugs. To further exploit this data for human health and disease, there is a need to understand the genome data itself in detail, discover novel targets, and understand their role in physiological pathways and associated diseases with the aim of translating these discoveries to clinical and preventive medicine. It is equally important to understand the labors and limitations in integrating clinical phenotypes with genomic, transcriptomic, proteomic, and metabolomic approaches. Post-genomic Approaches to Drug and Vaccine Development focuses on some key advances in the field.
Technical topics discussed in the book include: - Drug discovery - Target identification and prioritization - Hypothesis driven multi-target drug design - Genomics in vaccine development - Gene regulatory networks - Vaccine design and development - Prediction of drug side effects in silico
Автор: Smith, Moyra (division Of Genetic And Genomic Medicine, Department Of Pediatrics, University Of California Irvine, Irvine, Ca, Usa) Название: Progress in genomic medicine ISBN: 0323915477 ISBN-13(EAN): 9780323915472 Издательство: Elsevier Science Рейтинг: Цена: 19370.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Progress in Genomic Medicine: From Research to Clinical Application provides a careful synthesis of the foundations, current trends and translational challenges in genomic medicine, clarifying pathways forward and enabling genomic medicine research and implementation across clinical settings and treatment development. Sections address the history and growth of genetic medicine, with a discussion of key studies in syndrome delineations, inherited diseases, biochemical genetics, and chromosome abnormalities, overview clinical applications made possible through genomic advances, with chapters on DNA sequencing for clinical genetic diagnosis, genotype-phenotype correlations in individuals and across populations, new-born screening for treatable genetic disorders, and more.
In addition, social, ethical and public health aspects of applying genomic technologies are included throughout. Here, Dr. Smith applies her experience and participation in the field, across its major milestones, to put current research, clinical advances, and ongoing questions in context.
Описание: Sudden cardiac death is the leading cause of non-traumatic mortality in young (This book aims to provide an overview of the genetic and clinical aspects of SCD in young athletes, with particular emphasis on the specific issues related to diagnosis and management that these unique group of individuals pose to a physician. Specific diagnostic and management dilemmas will be illustrated through clinical cases and the most up-to-date guidelines regarding participation in sport outlined.
Описание: This book is the output of Anthropological Survey of India`s National Project "DNA Polymorphism of Contemporary Indian Population" conducted during 2000 to 2018.
Автор: Yihong Yao Название: Genomic Biomarkers for Pharmaceutical Development, ISBN: 0123973368 ISBN-13(EAN): 9780123973368 Издательство: Elsevier Science Рейтинг: Цена: 11193.00 р. Наличие на складе: Нет в наличии.
Описание: Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development. . With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development.
Автор: Reena Das, Prashant Sharma Название: Molecular Genetics of Thalassemia Syndromes ISBN: 1615047247 ISBN-13(EAN): 9781615047246 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 3762.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Reviews the molecular genetics of the thalassemia syndromes, inherited hemoglobin disorders that comprise the commonest monogenic disorders globally. Thalassemias are found in high frequencies in tropical regions corresponding to the malaria belt.
Автор: Meena Balasubramanian Название: Clinical and Molecular Heterogeneity of Osteogenesis Imperfecta ISBN: 1615047441 ISBN-13(EAN): 9781615047444 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 3762.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Osteogenesis imperfecta (OI) is a disease encompassing a group of disorders mainly characterized by bone fragility and is the commonest form of heritable bone fragility. In this book, the clinical presentations with particular emphasis on rare phenotypes associated with OI are discussed together with molecular advances in diagnosis and treatment of OI.
Автор: Ramaswamy Govindan, Siddhartha Devarakonda Название: Cancer genomics for the clinician ISBN: 0826168671 ISBN-13(EAN): 9780826168672 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 7484.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A practical guide to cancer genomics and its application to cancer diagnosis and care. Each chapter provides explanations of concepts, terminology, and methods. Also included are tips for interpreting and analysing molecular data, and discussion of molecular predictors for targeted therapies covering haematologic malignancies and solid tumours.
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