Molecular Targets In Protein Misfolding And Neurodegenerative Disease, Seneci,Pierfausto
Автор: Sewell, Robert D. E. Название: Protein Misfolding in Neurodegenerative Diseases ISBN: 0849373107 ISBN-13(EAN): 9780849373107 Издательство: Taylor&Francis Рейтинг: Цена: 35983.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Название: Protein Misfolding in Neurodegenerative Diseases ISBN: 036738812X ISBN-13(EAN): 9780367388126 Издательство: Taylor&Francis Рейтинг: Цена: 10411.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Research focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact.
Protein Misfolding inNeurodegenerative Diseases: Mechanisms and Therapeutic Strategies addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments, including the recognition of protein misfolding as both a marker and a causal agent, the text presents the work of those who are actively pursuing more effective treatments, as well as preventative measures, and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals, as well as the potential role of various inhibitors and NSAIDS.
A Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding
Divided into five sections, this groundbreaking text provides up-to-date accounts for Alzheimer's, Parkinson's, Huntington's, Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors, including oxidative stress, play a role in these complex diseases.
Автор: Richard I. Morimoto; Yves Christen Название: Protein Quality Control in Neurodegenerative Diseases ISBN: 3642447066 ISBN-13(EAN): 9783642447068 Издательство: Springer Рейтинг: Цена: 17096.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer`s disease, Parkinson`s disease, amyotrophic lateral sclerosis, Huntington`s disease, and other diseases of protein conformation.
Автор: Baekelandt, Veerle Название: Disease-Modifying Targets in Neurodegenerative Disorders ISBN: 0128051205 ISBN-13(EAN): 9780128051207 Издательство: Elsevier Science Рейтинг: Цена: 11706.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Disease-Modifying Targets in Neurodegenerative Disorders: Paving the Way for Disease-Modifying Therapies examines specific neurodegenerative disorders in comprehensive chapters written by experts in the respective fields. Each chapter contains a summary of the disease management field, subsequently elaborating on the molecular mechanisms and promising new targets for disease-modifying therapies.
This overview is ideal for neuroscientists, biomedical researchers, medical doctors, and caregivers, not only providing readers with a summary of the way patients are treated today, but also offering a glance at the future of neurodegenerative disorder treatment.
Provides a comprehensive overview of how key proteins in neurodegenerative disorders can be used as targets to modify disease progress
Summarizes how patients are treated today, providing a glance at future disease management
Includes intelligible and informative information that is perfect for non-specialists, medical practitioners, and scientists
Written and peer reviewed by outstanding scientists in their respective fields
Автор: V.M.-Y. Lee; J.Q. Trojanowski; L. Buee; Y. Christe Название: Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders ISBN: 3642086497 ISBN-13(EAN): 9783642086496 Издательство: Springer Рейтинг: Цена: 29150.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this volume are contributions based on a meeting arranged by the WHO and the Fondation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer`s Disease, Chromosome 17-Linked Dementia, Parkinson`s Disease and disorders with tauopathies.
Автор: Gary Fiskum Название: Neurodegenerative Diseases ISBN: 0306452987 ISBN-13(EAN): 9780306452987 Издательство: Springer Рейтинг: Цена: 26216.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the Fifteenth Washington International Spring Symposium held at The George Washington University, Washington, D.C., May 15-17, 1995
Автор: Daniela Galimberti; Elio Scarpini Название: Neurodegenerative Diseases ISBN: 1447172426 ISBN-13(EAN): 9781447172420 Издательство: Springer Рейтинг: Цена: 14635.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer`s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases.
Автор: Teplow, David B. Название: Molecular Biology Of Neurodegenerative Diseases,107 ISBN: 0123858836 ISBN-13(EAN): 9780123858832 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Нет в наличии.
Описание: Neurodegenerative diseases result in progressive degeneration and/or death of nerve cells which leads to problems with movement and mental functioning. This volume reviews the research and developments in the molecular biology of neurodegenerative diseases.
Prions and Neurodegenerative Diseases, Volume 172, in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Cell-free amplification of prions: where do we stand? Transgenic mouse models for the study of prion diseases and much more.
Автор: Adejare, Adeboye Название: Drug Discovery Approaches for the Treatment of Neurodegenerative ISBN: 0128028106 ISBN-13(EAN): 9780128028100 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer's Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer's Disease and illustrating the paradigm necessary to ensure future research and treatment success.
The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer's Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer's Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders.
Автор: Michael J. Hurley Название: Omic Studies of Neurodegenerative Disease - Part B,122 ISBN: 0128047623 ISBN-13(EAN): 9780128047620 Издательство: Elsevier Science Рейтинг: Цена: 24423.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Omic Studies of Neurodegenerative Disease: Part B is part of a well-established international series on neuroscience that examines major areas of basic and clinical research, along with emerging and promising subfields.
The book informs the reader on the current state of the studies used to evaluate the mechanisms, causes, and treatment of neurodegeneration through a combination of literature reviews and examples of current research.
Автор: Mathias Jucker; Yves Christen Название: Proteopathic Seeds and Neurodegenerative Diseases ISBN: 3642446965 ISBN-13(EAN): 9783642446962 Издательство: Springer Рейтинг: Цена: 19376.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details the latest research on prion diseases and presents developing therapies. It includes contributions from Nobel Laureates Eric Kandel and Stanley Prusiner.
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