Strategies To Modify The Drug Release From Pharmaceutical Systems, Bruschi,Marcos Luciano
Новое издание
Автор: By Marcos Luciano Bruschi, PhD, Professor of Pharm Название: Strategies to Modify the Drug Release from Pharmaceutical Systems ISBN: 0443333572 ISBN-13(EAN): 9780443333576 Издательство: Elsevier Science Цена: 27118.00 р. Наличие на складе: Нет в наличии. Описание: Strategies to Modify the Drug Release from Pharmaceutical Systems, Second Edition serves as a vital reference on contemporary models aimed at achieving the precise therapeutic dosage and timing of drug release. The book provides updated strategies, mathematical models, routes of administration, and technologies, all presented succinctly and objectively. This six-chapter guide covers general concepts of drug release modification and classification of therapeutic systems, including passive versus active targeting. It delves into mechanisms to control drug release, discussing materials and technologies, and introduces mathematical and physicochemical models of drug release.Furthermore, it reviews drug delivery systems like 3D printing, nose-to-brain delivery, environmentally responsive systems, and new lipid systems, making it indispensable for pharmaceutical scientists, graduate students, materials scientists, and chemists.
Автор: Watson David G. Название: Pharmaceutical Analysis. 5 ed ISBN: 0702078077 ISBN-13(EAN): 9780702078071 Издательство: Elsevier Science Рейтинг: Цена: 5305.00 р. 7578.00-30% Наличие на складе: Есть (5 шт.) Описание: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. The mathematics involved is notoriously difficult, but this much-praised textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Two new chapters have been added to the new edition covering methods used in the quality control of biotechnologically produced drugs, and electrochemical biosensors. There is continuous learning reinforcement throughout the book by way of worked calculation examples and self-assessment test questions. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes Two new chapters: Chapter 16 Methods used in the quality control of biotechnologically produced drugs Chapter 17 Electrochemical biosensors
Описание: A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective.
Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
Описание: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals.
The mathematics involved is notoriously difficult, but this much-praised textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Two new chapters have been added to the new edition covering methods used in the quality control of biotechnologically produced drugs, and electrochemical biosensors. There is continuous learning reinforcement throughout the book by way of worked calculation examples and self-assessment test questions.
Описание: With contributions from leading experts, this book is the first to focus solely on addressing the problems and reviewing the strategies currently being used to improve the delivery of antisense nucleic acids. Important delivery issues, such as improving biological stability, improving cell-specific targeting and cellular uptake, manipulating subcellular distribution and producing liposomal delivery systems for antisense agents are comprehensively covered in this volume. This book links review-type articles with contributions that contain exciting never-before-published data on the cellular delivery of oligonucleotides. It stimulates reading for both established researchers and newcomers to the antisense field.
Автор: Nayak, Amit Kumar Название: Advances And Challenges In Pharmaceutical Technology ISBN: 012820043X ISBN-13(EAN): 9780128200438 Издательство: Elsevier Science Рейтинг: Цена: 26107.00 р. Наличие на складе: Нет в наличии.
Описание:
Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms.
Автор: Douroumis Название: Drug Delivery Strategies for Poorly Water-Soluble Drugs ISBN: 0470711973 ISBN-13(EAN): 9780470711972 Издательство: Wiley Рейтинг: Цена: 22326.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability one of the most significant hurdles in drug discovery and development.
Автор: Rathbone, Michael Название: Modified-Release Drug Delivery Technology ISBN: 1420044354 ISBN-13(EAN): 9781420044355 Издательство: Taylor&Francis Рейтинг: Цена: 26796.00 р. Наличие на складе: Нет в наличии.
Автор: Rathbone, Michael J. Название: Modified-Release Drug Delivery Technology ISBN: 1420053558 ISBN-13(EAN): 9781420053555 Издательство: Taylor&Francis Рейтинг: Цена: 30624.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Webster Название: Poorly Soluble Drugs ISBN: 9814745456 ISBN-13(EAN): 9789814745451 Издательство: Taylor&Francis Рейтинг: Цена: 31390.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
This book is the first text to provide a comprehensive assessment of the application of fundamental principles of dissolution and drug release testing to poorly soluble compounds and formulations. Such drug products are, vis- -vis their physical and chemical properties, inherently incompatible with aqueous dissolution. However, dissolution methods are required for product development and selection, as well as for the fulfillment of regulatory obligations with respect to biopharmaceutical assessment and product quality understanding. The percentage of poorly soluble drugs, defined in classes 2 and 4 of the Biopharmaceutics Classification System (BCS), has significantly increased in the modern pharmaceutical development pipeline. This book provides a thorough exposition of general method development strategies for such drugs, including instrumentation and media selection, the use of compendial and non-compendial techniques in product development, and phase-appropriate approaches to dissolution development.
Emerging topics in the field of dissolution are also discussed, including biorelevant and biphasic dissolution, the use on enzymes in dissolution testing, dissolution of suspensions, and drug release of non-oral products. Of particular interest to the industrial pharmaceutical professional, a brief overview of the formulation and solubilization techniques employed in the development of BCS class 2 and 4 drugs to overcome solubility challenges is provided and is complemented by a collection of chapters that survey the approaches and considerations in developing dissolution methodologies for enabling drug delivery technologies, including nanosuspensions, lipid-based formulations, and stabilized amorphous drug formulations.
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