Methods For Monitoring Mitochondrial Functions During Pathogen Infection,188, Marchi,Saverio
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 30624.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Mayevsky Название: Hyperbaric Oxygenation ISBN: 3031496809 ISBN-13(EAN): 9783031496806 Издательство: Springer Рейтинг: Цена: 17074.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Exposure of patients to a high oxygen environment is a standard treatment in a select group of patients. The development of oxygen toxicity must be avoided in those patients. This book describes the effects of normobaric and hyperbaric oxygen treatment of animal models on brain biochemical and physiological responses. This book provides a summary of our knowledge on the effects of hyperbaric oxygenation on mitochondrial activity in vivo, and other functions of the brain. A chapter covering the use of hyperbaric hyperoxia in patients’ brain pathology and care is also included. This is an ideal book for students, research groups, and clinicians studying hyperbaric oxygen and its connection to mitochondrial activity and brain physiological functions.
Автор: Palmeira Carlos M., Rolo Anabela P. Название: Mitochondrial Regulation: Methods and Protocols ISBN: 1071614320 ISBN-13(EAN): 9781071614327 Издательство: Springer Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book integrates mitochondria with other cellular components, discussing the dynamic properties of mitochondria with an emphasis on how these processes respond to signaling events and how they affect cellular metabolism.
Автор: Patrick Lestienne Название: Mitochondrial Diseases ISBN: 3642641660 ISBN-13(EAN): 9783642641664 Издательство: Springer Рейтинг: Цена: 13677.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: For those like me who witnessed the beginning of the adventure of human mitochon- drial pathology, one can only be astounded by the extent and unexpectedness of what the field has come to offer. Extent because nobody could have imagined the sheer size of the domain. Unexpectedness because hitherto it was impossible to imagine the clinical polymorphism that this pathology would represent. The starting point was clear. Initially, there was the exceptional, and for a long time unique, observation of euthyroidian hypermetabolism that Luft and colleagues analyzed remarkably in biochemical and clinical terms. Thereafter, there was the support provided by the electron microscopy studies of Afzelius, and the very first visualization of mitochondrial abnormalities. That was way back in 1958. A few years later, progress in the cytology and cytochemistry of skeletal muscle tissue was to provide the means of detecting such abnormalities by examining sections with light microscopy. The colorful term "ragged red fibers", coined by W. K. Engel, became uni- versally accepted, and this typical aspect with Gomori trichrome stain was to throw light on the frequency with which these mitochondrial abnormalities could occur under pathological conditions which, until then, had remained a total mystery regard- ing their mechanism: syndromes such as the ocular myopathies with their descending evolution and the oculocraniosomatic syndromes. We were at the beginning of the 1970s.
Автор: Carlos M. Palmeira; Anabela P. Rolo Название: Mitochondrial Regulation ISBN: 1493946129 ISBN-13(EAN): 9781493946129 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Isolation of Crud Mitochondrial Fraction from Cells
Mariusz R. Wieckowski and Lech Wojtczak
2. Isolation of Mitochondria from Liver and Extraction of Total RNA and Protein - Analyses of MicroRNA and Protein Expressions
Pedro M. Borralho, Clifford J. Steer, and Cecнlia M. P. Rodrigues
3. PCR Based Determination of Mitochondrial DNA Copy Number in Multiple Species
5. Measuring PGC-1α and its Acetylation Status in Mouse Primary Myotubes
Ana P. Gomes and David A. Sinclair
6. Measurement of Mitochondrial Oxygen Consumption Rates in Mouse Primary Neurons and Astrocytes
Sofia M. Ribeiro, Alfredo Gimйnez-Cassina, and Nika N. Danial
7. Determination Of Oxidative Phosphorylation Complexes Activities
Joгo S. Teodoro, Carlos M. Palmeira, and Anabela P. Rolo
8. Histoenzymatic Methods for Visualization of the Activity of Individual Mitochondrial Respiratory Chain Complexes in the Muscle Biopsies from Patients with Mitochondrial Defects
Agnieszka Karkucinska-Wieckowska, Maciej Pronicki, and Mariusz R. Wieckowski
9. A Method Aimed at Assessing the Functional Consequences of the Supramolecular Organization of the Respiratory Electron Transfer Chain by Time-resolved Studies
Fabrice Rappaport
10. BN-PAGE-based Approach to Study Thyroid Hormones and Mitochondrial Function
Elena Silvestri, Assunta Lombardi, Federica Cioffi, and Fernando Goglia
11. Detection of UCP1 Protein and Measurements of Dependent GDP-Sensitive Proton Leak in Non-Phosphorylating Thymus Mitochondria
Kieran J. Clarke, Audrey M. Carroll, Gemma O'Brien & Richard K. Porter
12. Exploring Liver Mitochondrial Function By 13c-Stable Isotope Breath Tests. Implications In Clinical Biochemistry
Ignazio Grattagliano, Leonilde Bonfrate, Michele Lorusso, Luigi Castorani, Ornella de Bari, and Piero Portincasa
13. Following Mitochondria Dynamism: Confocal Analysis of The Organelle Morphology
F. R. Mariotti, M. Corrado, and S. Campello
14. Analysis of Pro-apoptotic Protein Trafficking to and From Mitochondria
Ignacio Vega-Naredo, Teresa Cunha-Oliveira, Teresa Serafim, Vilma Sardao, and Paulo J. Oliveira
15. Mitophagy and Mitochondrial Balance
Simone Patergnani and Paolo Pinton
Автор: Lee-Jun C. Wong Название: Mitochondrial Disorders ISBN: 1493959506 ISBN-13(EAN): 9781493959501 Издательство: Springer Рейтинг: Цена: 17684.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The variability of clinical symptoms in mitochondrial diseases calls for a systematic presentation of the full range of protocols used in their assessment. This volume provides cutting-edge methods of analysis as well as expert guidance on how to apply them.
Автор: House, Patrick Название: Mitochondrial Regulation ISBN: 1071614355 ISBN-13(EAN): 9781071614358 Издательство: Springer Рейтинг: Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book integrates mitochondria with other cellular components, discussing the dynamic properties of mitochondria with an emphasis on how these processes respond to signaling events and how they affect cellular metabolism.
Автор: Allison, William S. Название: Mitochondrial Function, Part A,456 ISBN: 0080877761 ISBN-13(EAN): 9780080877761 Издательство: Elsevier Science Рейтинг: Цена: 26275.00 р. Наличие на складе: Нет в наличии.
Описание: Presents modern methods that have been developed to examine mitochondrial electron transport chain complexes, iron-sulfur proteins and reactive oxygen species. This title is suitable for researchers in all fields of life sciences.
Автор: Palmeira Название: Mitochondrial Bioenergetics ISBN: 1493978306 ISBN-13(EAN): 9781493978304 Издательство: Springer Рейтинг: Цена: 20733.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Preface...Table of Contents...Contributing Authors... 1. Overview of Mitochondrial BioenergeticsVitor M.C. Madeira 2. Evaluation of Respiration with Clark Type Electrode in Isolated Mitochondria and Permeabilized Animal CellsAna M. Silva and Paulo J. Oliveira 3. High-Resolution FluoRespirometry and OXPHOS Protocols for Human Cells, Permeabilized Fibres from Small Biopsies of Muscle and Isolated MitochondriaCarolina Doerrier, Luiz F. Garcia-Souza, Gerhard Krumschnabel, Yvonne Wohlfarter, Andrбs T. Mйszбros, and Erich Gnaiger 4. High-Throughput Analysis of Mitochondrial Oxygen ConsumptionJames Hynes, Rachel L. Swiss, and Yvonne Will 5. Modulation of Cellular Respiration by Endogenously Produced Nitric Oxide in Rat Hippocampal SlicesAna Ledo, Rui M. Barbosa, and Joгo Laranjinha 6. Mitochondrial Membrane Potential (ΔΨ) Fluctuations Associated with the Metabolic States of MitochondriaJoгo S. Teodoro, Anabela P. Rolo, and Carlos M. Palmeira 7. Fluorescence Measurement of Mitochondrial Membrane Potential Changes in Cultured CellsDavid G. Nicholls 8. Comparison of Mitochondrial Incubation Media for Measurement of Respiration and Hydrogen Peroxide ProductionTimea Komlуdi, Ondrej Sobotka, Gerhard Krumschnabel, Nicole Bezuidenhout, Elisabeth Hiller, Carolina Doerrier, and Erich Gnaiger 9. Measurement of Proton Leak in Isolated MitochondriaCharles Affourtit, Hoi-Shan Wong, and Martin D. Brand 10. Imaging Mitochondrial Calcium Fluxes with Fluorescent Probes and Single or Two Photon Confocal MicroscopySean M. Davidson and Michael R. Duchen 11. Mitochondrial Permeability Transition Pore and Calcium HandlingRandi J. Parks, Elizabeth Murphy, and Julia C. Liu 12. Redox Equivalents and Mitochondrial BioenergeticsJames R. Roede, Young-Mi Go, and Dean P. Jones 13. Mitochondrial Bioenergetics by 13 C-NMR Isotopomer AnalysisRui A. Carvalho 14. Computational Modeling of Mitochondrial Function from a Systems Biology PerspectiveSonia Cortassa, Steven J. Sollott, and Miguel A. Aon 15. Monitoring the Mitochondrial Dynamics in Mammalian CellsLuca Simula and Silvia Campello 16. Plate-Based Measurement of Superoxide and Hydrogen Peroxide Production by Isolated MitochondriaHoi-Shan Wong, Pierre-Axel Monternier, Adam L. Orr, and Martin D. Brand 17. Plate-Based Measurement of Respiration by Isolated MitochondriaShona A. Mookerjee, Casey L. Quinlan, Helen Wong, Pratiksha Dighe, and Martin D. Brand 18. Detection of Iron Depletion- and Hypoxia-Induced Mitophagy in Mammalian CellsShun-ichi Yamashita and Tomotake Kanki 19. The Importance of Calcium Ions for Determining Mitochondrial Glycerol-3-Phosphate Dehydrogenase Activity When Measuring Uncoupling Protein 1 (UCP1) Function in Mitochondria Isolated from Brown Adipose TissueKieran J. Clarke and Richard K. Porter 20. Isolation and Analysis of Mitochondrial Small RNAs from Rat Liver Tissue and HepG2 CellsJulian Geiger and Louise T. Dalgaard 21. Imaging of Mitochondrial pH Using SNARF-1Venkat K. Ramshesh and John J. Lemasters 22. Relation between Mitochondrial Membrane Potential and ROS FormationJan Suski, Magdalena Lebiedzinska, Massimo Bonora, Paolo Pinton, Jerzy Duszynski, and Mariusz R. Wieckowski
Автор: Allison, William S. Название: Mitochondrial Function, Part B,457 ISBN: 0123746221 ISBN-13(EAN): 9780123746221 Издательство: Elsevier Science Рейтинг: Цена: 26275.00 р. Наличие на складе: Нет в наличии.
Описание: Presents methods that have been developed to assess the number and function of nuclear-encoded proteins in the mitochndrion. This work focuses on regulation of mitochondrial function and mitochondrial diseases. It includes a section emphasizing the mitochondrial defects associated with type-2 diabetes.
Автор: Green, George Dawes Название: Mitochondrial Medicine ISBN: 1071612646 ISBN-13(EAN): 9781071612644 Издательство: Springer Рейтинг: Цена: 18904.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This second edition offers 88 chapters divided among three volumes providing the most comprehensive source of know-how in the wide-ranging field of Mitochondrial Medicine.
Автор: Volkmar Weissig; Marvin Edeas Название: Mitochondrial Medicine ISBN: 1493922874 ISBN-13(EAN): 9781493922871 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This expert volume covers an interdisciplinary and rapidly growing area of biomedical research comprising genetic, biochemical, pathological, and clinical studies aimed at the diagnosis and therapy of human diseases which are either caused by or associated with mitochondrial dysfunction.
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