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Biopharmaceuticals in Plants, Hefferon, Kathleen Laura


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Автор: Hefferon, Kathleen Laura
Название:  Biopharmaceuticals in Plants
ISBN: 9781439804742
Издательство: Taylor&Francis
Классификация:


ISBN-10: 1439804745
Обложка/Формат: Hardback
Страницы: 228
Вес: 0.52 кг.
Дата издания: 10.11.2009
Язык: English
Иллюстрации: 20 tables, black and white; 4 illustrations, color; 22 illustrations, black and white
Размер: 244 x 166 x 21
Читательская аудитория: Postgraduate, research & scholarly
Подзаголовок: Toward the next century of medicine
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Поставляется из: Европейский союз


Biopharmaceuticals in Plants

Автор: Hefferon
Название: Biopharmaceuticals in Plants
ISBN: 1138114952 ISBN-13(EAN): 9781138114951
Издательство: Taylor&Francis
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Цена: 12861.00 р.
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Описание:

Transgenic plants present enormous potential to become one of the most cost-effective and safe systems for large-scale production of proteins for industrial, pharmaceutical, veterinary, and agricultural uses. Over the past decade, much progress has been made with respect to the development of vaccines, antibodies, and other therapeutic proteins. Biopharmaceuticals in Plants: Toward the Next Century of Medicine provides a comprehensive survey of all major aspects of the development and production of plant-made biopharmaceuticals.

Accompanied by an exhaustive list of references to facilitate further study, this critical volume:

  • Describes the theory and practice of modern plant transformation techniques with respect to nuclear and plastic genomes
  • Outlines the steps involved in the generation of transgenic plants
  • Discusses the engineering of plant virus expression vectors for transient expression of vaccine proteins and other therapeutics in plant tissue
  • Addresses the significant role of glycosylation in the production of plant-made mammalian proteins
  • Investigates the basis of mucosal immunity using plant-based oral vaccines
  • Examines the scale-up of plant-derived vaccine and therapeutic proteins in entire crops or in large batch cell suspension cultures
  • Explores the development of clinical trials utilizing plant-derived biopharmaceutical proteins
  • Evaluates risks and biosafety concerns regarding plant-derived pharmaceuticals

The book concludes with a discussion of the future of plant-based vaccines and other therapeutic proteins with respect to commercial viability and as a tool to improve global public health. Far-reaching in its scope, this text is a baseline reference that students and researchers in a broad range of fields such as medicine, plant science, biotechnology, crop science, natural products chemistry, and engineering will consult regularly. It will also serve as a useful tool for individuals and companies seeking to invest in this dynamic area.

Glycosylation Engineering of Biopharmaceuticals

Автор: Alain Beck
Название: Glycosylation Engineering of Biopharmaceuticals
ISBN: 1493962663 ISBN-13(EAN): 9781493962662
Издательство: Springer
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Цена: 14635.00 р.
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Описание: Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols serves as an ideal guide for scientists striving to push forward the exciting field of engineered biopharmaceuticals.

Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts

Автор: Komives
Название: Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts
ISBN: 1118361989 ISBN-13(EAN): 9781118361986
Издательство: Wiley
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Цена: 19000.00 р.
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Biophysical Characterization Of Proteins In Developing Biopharmaceuticals

Автор: Houde, Damian J.
Название: Biophysical Characterization Of Proteins In Developing Biopharmaceuticals
ISBN: 0444641734 ISBN-13(EAN): 9780444641731
Издательство: Elsevier Science
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Цена: 32844.00 р.
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Описание:

Biophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure, this book explains the best way to achieve this goal using key methods commonly employed in the biopharmaceutical industry. This book will help today's industrial scientists plan a career in this industry and successfully implement these biophysical methodologies. This updated edition has been fully revised, with new chapters focusing on the use of chromatography and electrophoresis and the biophysical characterization of very large biopharmaceuticals.

In addition, best practices of applying statistical analysis to biophysical characterization data is included, along with practical issues associated with the concept of a biopharmaceutical's developability and the technical decision-making process needed when dealing with biophysical characterization data.

Immunogenicity of Biopharmaceuticals

Автор: Marco Weert; Eva Horn M?ller
Название: Immunogenicity of Biopharmaceuticals
ISBN: 1441926089 ISBN-13(EAN): 9781441926081
Издательство: Springer
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Цена: 22796.00 р.
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Описание: Immunogenicity of Biopharmaceuticals is the first book to comprehensively address the potential of an immune response to biopharmaceuticals.

Mucosal Delivery of Biopharmaceuticals

Автор: Jos? das Neves; Bruno Sarmento
Название: Mucosal Delivery of Biopharmaceuticals
ISBN: 1489978380 ISBN-13(EAN): 9781489978387
Издательство: Springer
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Цена: 20516.00 р.
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Описание:

.-1. Concepts in Mucosal Immunity and Mucosal Vaccines
.-Simona Gallorini, Derek T. O'Hagan, Barbara C. Baudner

.-2. Mucoadhesion and Characterization of Mucoadhesive Properties
.-Tao Yu, Gavin P. Andrews, David S. Jones

.-3. Mucus as a Barrier for Biopharmaceuticals and Drug Delivery Systems
.-Hongbo Zhang, Mohammed-Ali Shahbazi, Patrick Almeida, Hйlder A. Santos

.-4. Epithelial Permeation and Absorption Mechanisms of Biopharmaceuticals
.-Hanne M rck Nielsen

.-5. Oral Delivery of Biopharmaceuticals
.-Catarina Oliveira Silva, Bruno Sarmento, Catarina Pinto Reis

.-6. Buccal Delivery of Biopharmaceuticals: Vaccines and Allergens
.-Sevda Şenel, Merve Cansız, Michael J. Rathbone

.-7. Pulmonary Delivery of Biopharmaceuticals
.-Fernanda Andrade, Catarina Moura, Bruno Sarmento

.-8. Nasal Delivery of Biopharmaceuticals
.-Eiji Yuba, Kenji Kono

.-9. Ocular Delivery of Biopharmaceuticals
.-Holly Lorentz, Heather Sheardown

.-10. Vaginal Delivery of Biopharmaceuticals
.-Josй das Neves

.-11. Nanoparticles-in-Microsphere Oral Delivery Systems (NiMOS) for Nucleic Acid Therapy in the Gastrointestinal Tract
.-Shardool Jain, Mansoor Amiji

.-12. Bacteria-Based Vectors for Oral Gene Therapy
.-Yong Bai, Rachael Burchfield, Sangwei Lu, Fenyong Liu

.-13. Self-Assembled Polysaccharide Nanogels for Nasal Delivery of Biopharmaceuticals
.-Tomonori Nochi, Yoshikazu Yuki, Kazunari Akiyoshi, Hiroshi Kiyono

.-14. Pheroid(TM) Vesicles and Microsponges for Nasal Delivery of Biopharmaceuticals
.-Lissinda H. du Plessis, Awie F. Kotzй

.-15. Delivery Strategies for Developing siRNA-Based Vaginal Microbicides
.-Joseph A Katakowski, Deborah Palliser

.-16. Delivery Strategies for Developing Vaginal DNA Vaccine Combining Cell-Penetrating Peptides and Jet Injection
.-Takanori Kanazawa, Hiroaki Okada

.-17. Vaccine Delivery Systems for Veterinary Immunization
.-Juan M. Irache, Ana I. Camacho, Carlos Gamazo

.-18. Eligen(R) Technology for Oral Delivery of Proteins and Peptides
.-Sunita Prem Victor, Willi Paul, and Chandra P. Sharma

.-19. The RapidMist(TM) System for Buccal Delivery of Insulin
.-Meena Bansal, Sanjay Bansal, Rachna Kumria

.-20. The Pharmaceutical Development of rhDNase (Dornase Alpha) for the Treatment of Cystic Fibrosis
.-Steven J. Shire, Thomas M. Scherer

.-21. Development of the Exubera(R) Insulin Pulmonary Delivery System
.-Cynthia L. Stevenson, David Bennett

.-22. Technosphere(R) An Inhalation System for Pulmonary Delivery of Biopharmaceuticals
.-Antуnio J. Almeida, Ana Grenha

.-23. ChiSys(R) as a Chitosan-Based Delivery Platform for Nasal Vaccination
.-Peter Watts, Alan Smith, Michael Hinchcliffe

.-24. Development of a Cationic Nanoemulsion Platform (Novasorb(R)) for Ocular Delivery
.-Frйdйric Lallemand, Philippe Daull, Jean-Sйbastien Garrigue

.-25. Regulatory Aspects and Approval of Biopharmaceuticals for Mucosal Delivery: Quality, Toxicology and Clinical Aspects
.-Karen Brigitta Goetz, Yuansheng Sun, Katrin Fйchir, Evelyne Kretzschmar, Isabel Buettel

Perfusion Cell Culture Processes for Biopharmaceuticals: Process Development, Design, and Scale-Up

Автор: Wolf Moritz, Bielser Jean-Marc, Morbidelli Massimo
Название: Perfusion Cell Culture Processes for Biopharmaceuticals: Process Development, Design, and Scale-Up
ISBN: 1108480039 ISBN-13(EAN): 9781108480031
Издательство: Cambridge University Press
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Цена: 27944.00 р.
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Описание: Master the design and operation of perfusion cell cultures with this authoritative reference. A perfect resource for groups active in the cell culture field, as well as graduate students in areas such as chemical engineering, biotechnology, chemistry and biology.

ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins - Applications in Drug Discovery and Development

Автор: Zhou
Название: ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins - Applications in Drug Discovery and Development
ISBN: 1118898648 ISBN-13(EAN): 9781118898642
Издательство: Wiley
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Цена: 19792.00 р.
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Process Validation in Manufacturing of Biopharmaceuticals

Автор: Rathore, Anurag S.
Название: Process Validation in Manufacturing of Biopharmaceuticals
ISBN: 1439850933 ISBN-13(EAN): 9781439850930
Издательство: Taylor&Francis
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Цена: 30624.00 р.
Наличие на складе: Нет в наличии.

The Challenge of CMC Regulatory Compliance for Biopharmaceuticals

Автор: John Geigert
Название: The Challenge of CMC Regulatory Compliance for Biopharmaceuticals
ISBN: 1461348048 ISBN-13(EAN): 9781461348047
Издательство: Springer
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Цена: 24392.00 р.
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Описание: In Chapter 1, the CMC regulatory process is explained, the breadth of products included under the umbrella ofbiopharmaceuticals are identified, and the track record for the pharmaceutical and biopharmaceutical industry in meeting CMC regulatory compliance is discussed.

Biotechnology and Biopharmaceuticals - Transforming Proteins and Genes into Drugs, Second Edition

Автор: Ho
Название: Biotechnology and Biopharmaceuticals - Transforming Proteins and Genes into Drugs, Second Edition
ISBN: 111817979X ISBN-13(EAN): 9781118179796
Издательство: Wiley
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Цена: 22010.00 р.
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Biopharmaceuticals, an Industrial Perspective

Автор: G. Walsh; B. Murphy
Название: Biopharmaceuticals, an Industrial Perspective
ISBN: 9048152372 ISBN-13(EAN): 9789048152377
Издательство: Springer
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Цена: 31915.00 р.
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Описание: This book provides a unique and up-to-date insight into the biopharmaceutical industry. Largely written by industrial authors, its scope is multidisciplinary, rendering it an ideal reference source for students undertaking advanced undergraduate or postgraduate courses in biotechnology, pharmaceutical science, biochemistry, or medicine.


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