Автор: Lee, Vincent Название: Peptide and Protein Drug Delivery ISBN: 0824778960 ISBN-13(EAN): 9780824778965 Издательство: Taylor&Francis Рейтинг: Цена: 19906.00 р. Наличие на складе: Нет в наличии.
Автор: Sara Bobone Название: Peptide and Protein Interaction with Membrane Systems ISBN: 3319064339 ISBN-13(EAN): 9783319064338 Издательство: Springer Рейтинг: Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria.
Автор: Sara Bobone Название: Peptide and Protein Interaction with Membrane Systems ISBN: 331938273X ISBN-13(EAN): 9783319382739 Издательство: Springer Рейтинг: Цена: 11397.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In her thesis, Sara Bobone outlines spectroscopic studies of antimicrobial peptides (AMPs) which are promising lead compounds for drugs used to fight multidrug resistant bacteria.
Автор: Rodney Pearlman; Y. John Wang Название: Stability and Characterization of Protein and Peptide Drugs ISBN: 148991238X ISBN-13(EAN): 9781489912381 Издательство: Springer Рейтинг: Цена: 25077.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Chris Van Der Walle Название: Peptide and Protein Delivery, ISBN: 0123849357 ISBN-13(EAN): 9780123849359 Издательство: Elsevier Science Рейтинг: Цена: 20379.00 р. Наличие на складе: Нет в наличии.
Описание: The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. This title addresses the routes for delivery of therapeutics. It covers cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery.
Автор: Rodney Pearlman; Y. John Wang Название: Stability and Characterization of Protein and Peptide Drugs ISBN: 0306443651 ISBN-13(EAN): 9780306443657 Издательство: Springer Рейтинг: Цена: 26216.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume attemptsto provide the formulation scientist with casehistories involving the use of therapeutic proteins and peptides that have been mar- keted or are under clinical testing. In previous volumes of this series, funda- mental theories and principles ofprotein characterization and stability were presented in depth by researchers in their fieldsofexpertise. The way from theory to practice isnot alwaysobvious and straightforward. There isa need for practical examples of how the principles and theories are put into use, specificallyin the development of a pharmaceutical product. It is our hope that this volume will fulfillsuch a need. Itisnot asimple task to choose a panel ofproteinsand peptides from the over 200 agents in human clinical trials. We have tried to collect a wide representation of molecules of different sizes-from 10 amino acids (Leu- prolide) to 1020 amino acids (Muromonab CD3). The examples include agents derived from various sources including monoclonal antibodies (Mur- omonab CD3), recombinant DNA (human and bovine growth hormones), natural source (fibrolase), and chemical synthesis (Leuprolide). Clearly this list is not intended to be encyclopedic. It isthe first time a collection of this sort has been made accessibleto the formulation scientists involved in devel- oping protein and peptide products. Although each chapter in this volume focuses primarily on the charac- terization and stability of a specific molecule, each has unique aspects.
Автор: Laszlo Otvos Название: Peptide-Based Drug Design ISBN: 1617378690 ISBN-13(EAN): 9781617378690 Издательство: Springer Рейтинг: Цена: 17684.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Due to their high specificity and low toxicity profile, peptides are once more central to the development of new drugs. Comprehensive and up-to-date, this practical volume provides scientists with a clear, concise guide for continuing this vital research.
Описание: Peptide Therapeutics is an essential reference work for students and researchers, in both academia and industry, with an interest in learning about Chemistry Manufacture and Control (CMC), and facilitating the development and manufacture of peptide-based drugs.
Автор: Laszlo Prokai; Katalin Prokai-Tatrai Название: Peptide Transport and Delivery into the Central Nervous System ISBN: 3034894201 ISBN-13(EAN): 9783034894203 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The general characteristics of neuropeptides are discussed as a background for the understanding of their role in regulation of physiological systems. The extent of those systems that are crucially affected by neuropeptides is vast and the complexity of their interactions makes the clinical focus on a specific neu- ropeptide unsatisfactory. The clinical potential of neuropeptides affecting eating disorders, eNS behavioral disorders and the neuroregenerative and neuroprotective action of neuropeptides is discussed. It is probable that suc- cessful neuropeptide therapeutics will depend upon the application of trans- lational and combinational research using various ingenious combinations and antagonists, neuropeptide receptor ago- of neuropeptides, their agonists nists and antagonists, improved methods of delivery and the development of peptides targeted to the genetic profile of individual patients. References 1 DeWied D (1969) Effects of peptide hormones on behavior. In: WF Ganong, L Martini (eds): Frontiers in Neuroendocrinology. Oxford University Press, New York, 97-140 2 Sandman CA, Schally AV, Kastin AJ, Miller L H (1972) A neuroendocrine influence on attention and memory. J Comp Physiol Psychol80: 54-58 3 Kastin AJ, Olson RD, SchaUy A V, Coy DH (1979) CNS effects of peripherally adminis- tered brain peptides. Life Sci 25: 401-414 4 Strand FL, Saint-Come C, Lee TS, Lee SJ, Kume JA, Zuccarelli LA (1993) An ACTH/MSH 4-10 analog BIM 22015 has neurotrophic and myotrophic attributes during peripheral nerve regeneration. Peptides 14: 287-296 5 Strand FL (1999) Neuropeptides: Regulators ofPhysiologjcal Processes.
Автор: Saravanan Ramachandran; Senthilkumar Rajagopal Название: Zebrafish: A Model for Marine Peptide Based Drug Screening ISBN: 9811378460 ISBN-13(EAN): 9789811378461 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Нет в наличии.
Описание: It also reviews the structure of marine peptides/toxins and the toxicology of peptide secreting cells and cells that respond to these enzymes, and describes the normal and abnormal toxicology of marine peptides in zebrafish models.
Автор: Jois Название: Peptide Therapeutics ISBN: 3031045432 ISBN-13(EAN): 9783031045431 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Нет в наличии.
Описание: This book explains how peptide-based drug design works, what steps are needed to develop a peptide-based therapeutic, and challenges in synthesis as well as regulatory issues. It covers the design concept of peptide therapeutics from fundamental principles using structural biology and computational approaches. The chapters are arranged in a linear fashion. A fresh graduate or a scientist who works on small molecules can use this to follow the design and development of peptide therapeutics to use as understanding the basic concepts. Each chapter is written by experts from academia as well as industry. Rather than covering extensive literature, the book provides concepts of design, synthesis, delivery, as well as regulatory affairs and manufacturing of peptides in a systematic way with examples in each case. The book can be used as a reference for a pharmaceutical or biomedical scientist or graduate student who wants to pursue their career in peptide therapeutics. Some chapters will be written as a combination of basic principles and protocol so that scientists can adopt these methods to their research work. The examples provided can be used to perform peptide formulation considerations for the designed peptides. The book has nine chapters, and each chapter can be read as an independent unit on a particular concept.
Автор: Mei-Chuan Ko; Girolamo Cal? Название: The Nociceptin/Orphanin FQ Peptide Receptor ISBN: 3030201856 ISBN-13(EAN): 9783030201852 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The aim of this book is not only to introduce readers with a broad spectrum of biological actions of the NOP receptor, but also to feature a detailed look at the N/OFQ-NOP receptor system, medicinal chemistry, pharmacology, and clinical data of NOP-targeted ligands. This special volume book - for the first time focusing on the NOP receptor - is designed to serve as a useful reference, stimulate more research on the N/OFQ-NOP receptor system, and lead to more development of NOP-related ligands for several therapeutic applications.
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