Автор: Vozza Lisa Et Al Название: How Medicines Are Born: The Imperfect Science Of Drugs ISBN: 1786342987 ISBN-13(EAN): 9781786342980 Издательство: World Scientific Publishing Рейтинг: Цена: 3643.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is an excursion into the drug development process, from the initial conception in a chemical or molecular biology lab, via tests in isolated cells and animals, to the stage of clinical trials. The human body is a complex ecosystem where little is conclusively known in terms of its response to medication, for both sick and healthy individuals. The considerable degree of uncertainty inherent in health-related research can lead to approval of controversial medicines, particularly in high-stakes scenarios and medical crises. Real-life examples are drawn on here to explain the decision making processes behind the acceptance of new drugs, disproving misconceptions around medicines by delving into the history and current practice of the drug development process.Originally written in Italian, How Medicines are Born helps patients, students, public health officials physicians, healthcare practitioners and biomedical scientists make informed decisions on the benefits and disadvantages of select medicine based on an understanding of the history of drug development.Published in Italian (2014), M D'Incalci & L Vozza, Come Nascono le Medicine; La scienza imperfetta dei farmaci. Bologna: Zanichelli
Автор: Kevin M.G. Taylor, Michael E. Aulton Название: Aulton`s pharmaceutics, 6th Edition ISBN: 070208154X ISBN-13(EAN): 9780702081545 Издательство: Elsevier Science Рейтинг: Цена: 9431.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
The essential pharmaceutics textbook
One of the world's best-known texts on pharmaceutics, Aulton's Pharmaceutics offers a complete course in one book for students in all years of undergraduate pharmacy and pharmaceutical sciences degrees.
Thoroughly revised, updated and extended by experts in their fields and edited by Professors Kevin Taylor and Michael Aulton, this new edition includes the science of formulation, pharmaceutical manufacturing and drug delivery.
All aspects of pharmaceutics are covered in a clear and readily accessible way and extensively illustrated throughout, providing an essential companion to the entire pharmaceutics curriculum from day one until the end of the course.
Fully updated throughout, with the addition of new chapters, to reflect advances in formulation and drug delivery science, pharmaceutical manufacturing and medicines regulation
Designed and written for newcomers to the design and manufacture of dosage forms
Relevant pharmaceutical science covered throughout
Includes the science of formulation and drug delivery
Reflects current practices and future applications of formulation and drug delivery science to small drug molecules, biotechnology products and nanomedicines
Key points boxes throughout
Over 400 online multiple choice questions
Fully updated throughout, with the addition of new chapters, to reflect advances in formulation and drug delivery science, pharmaceutical manufacturing and medicines regulation
Designed and written for newcomers to the design and manufacture of dosage forms
Relevant pharmaceutical science covered throughout
Includes the science of formulation and drug delivery
Reflects current practices and future applications of formulation and drug delivery science to small drug molecules, biotechnology products and nanomedicines
Key points boxes throughout
Over 400 online multiple choice questions
Автор: Francesco Clementi,Guido Fumagalli Название: General and Molecular Pharmacology: Principles of Drug Action ISBN: 1118768574 ISBN-13(EAN): 9781118768570 Издательство: Wiley Рейтинг: Цена: 20109.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with a particular attention to the mechanisms of drug action the fundamental basis for proper clinical use without neglecting toxicology and pharmacokinetics.
Автор: Ruhong Zhou Название: Modeling of Nanotoxicity ISBN: 3319348299 ISBN-13(EAN): 9783319348292 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a comprehensive overview of the fundamentals of nanotoxicity modeling and its implications for the development of novel nanomedicines.
Molecular Dynamics Simulation of Nanocomposites using BIOVIA Materials Studio, Lammps and Gromacs presents the three major software packages used for molecular dyanmics simulation of nanocomposites. Materials Studio, Lammps and Gromacs are all used for performing nanocomposites simulations and analysis. The purpose of this book is to provide the readers with an in-depth view of molecular dynamics modeling of nanocomposites using Materials Studio, Lammps and Gromacs. The book explains in detail how to use each of these packages most effectively, using real-world examples to show when each should be used. The latter two of these are open-source codes, which can be used for modelling at no cost.
As well as offering an introduction to molecular dynamics simulation, and explaining how it is applied to nanocomposites, the book includes several case studies, to show how each of the software packages are used to predict various properties of nanocomposites, including metal-matrix, polymer-matrix and ceramic-matrix based nanocomposites. The properties explored include mechanical, thermal, optical and electrical properties. The concept of perl scripting is discussed in detail. The questions this book answers for readers include:
Which module to use?
How do I perform optimization?
Which ensemble to use?
How do I calculate mechanical, thermal, optical and electrical properties?
How do I perform scripting in Materials Studio, Lammps and Gromacs?
This is the first book that explores methodologies for using Materials Studio, Lammps and Gromacs in the same place. It will be beneficial for students, researchers and scientists working in the field of molecular dynamics simulation.
Detailed explanation of basic commands and modules of Materials Studio, Lammps and Gromacs
Shows how Materials Studio, Lammps and Gromacs predict mechanical, thermal, electrical and optical properties of nanocomposites
Uses case studies to show which software should be used to solve a variety of nanoscale modelling problems
Описание: A comprehensive presentation of essential topics for biological engineers, focusing on the development and application of dynamic models of biomolecular and cellular phenomena.
This book describes the fundamental molecular and cellular events responsible for biological function, develops models to study biomolecular and cellular phenomena, and shows, with examples, how models are applied in the design and interpretation of experiments on biological systems. Integrating molecular cell biology with quantitative engineering analysis and design, it is the first textbook to offer a comprehensive presentation of these essential topics for chemical and biological engineering.
The book systematically develops the concepts necessary to understand and study complex biological phenomena, moving from the simplest elements at the smallest scale and progressively adding complexity at the cellular organizational level, focusing on experimental testing of mechanistic hypotheses. After introducing the motivations for formulation of mathematical rate process models in biology, the text goes on to cover such topics as noncovalent binding interactions; quantitative descriptions of the transient, steady state, and equilibrium interactions of proteins and their ligands; enzyme kinetics; gene expression and protein trafficking; network dynamics; quantitative descriptions of growth dynamics; coupled transport and reaction; and discrete stochastic processes. The textbook is intended for advanced undergraduate and graduate courses in chemical engineering and bioengineering, and has been developed by the authors for classes they teach at MIT and the University of Minnesota.
Описание: This book illustrates, in a comprehensive manner, the most crucial principles involved in pharmacology and allied sciences. The title begins by discussing the historical aspects of drug discovery, with up to date knowledge on Nobel Laureates in pharmacology and their significant discoveries. It then examines the general pharmacological principles - pharmacokinetics and pharmacodynamics, with in-depth information on drug transporters and interactions. In the remaining chapters, the book covers a definitive collection of topics containing essential information on the basic principles of pharmacology and how they are employed for the treatment of diseases.Readers will learn about special topics in pharmacology that are hard to find elsewhere, including issues related to environmental toxicology and the latest information on drug poisoning and treatment, analytical toxicology, toxicovigilance, and the use of molecular biology techniques in pharmacology. The book offers a valuable resource for researchers in the fields of pharmacology and toxicology, as well as students pursuing a degree in or with an interest in pharmacology.
Автор: Habasaki, Junko Название: Molecular Dynamics of Nanostructures and Nanoionics ISBN: 9814800775 ISBN-13(EAN): 9789814800778 Издательство: Taylor&Francis Рейтинг: Цена: 21284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book discusses complex nanostructured systems exemplified by nanoporous silicates, spontaneously formed gels from silica-nanocolloidal solutions, and related systems and examines them using molecular dynamics simulations.
Автор: James C Bonner; Jared M Brown Название: Interaction of Nanomaterials with the Immune System ISBN: 3030339610 ISBN-13(EAN): 9783030339616 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Interaction of Nanomaterials with the Immune System covers the most up to date information on our understanding of immune responses to ENMs across a wide range of topics including innate immunity, allergic immune responses, adaptive provides the reader with (1) up to date understanding of immune responses to ENMs;
Автор: Xu, Jun-Ping (School of Molecular Science, Arizona State University) Название: Cancer Inhibitors from Chinese Natural Medicines ISBN: 1032097396 ISBN-13(EAN): 9781032097398 Издательство: Taylor&Francis Рейтинг: Цена: 7808.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Nature is an attractive source of therapeutic and preventive compounds, and with such chemical diversity found in millions of species of plants, over 60% of currently used anticancer agents are derived from natural sources. Cancer Inhibitors from Chinese Natural Medicines summarizes new advancements in the experimental and clinical
Описание: Provides a pointed introduction to the fascinating subject of bottom- up nanotechnology with emphasis on the molecular-based study of condensed matter in small systems.
Описание: This set of six volumes provides a systematic and standardized description of 23,033 chemical components isolated from 6,926 medicinal plants, collected from 5,535 books/articles published in Chinese and international journals. A chemical structure with stereo-chemistry bonds is provided for each chemical component, in addition to conventional information, such as Chinese and English names, physical and chemical properties. It includes a name list of medicinal plants from which the chemical component was isolated. Furthermore, abundant pharmacological data for nearly 8,000 chemical components are presented, including experimental method, experimental animal, cell type, quantitative data, as well as control compound data. The seven indexes allow for complete cross-indexing. Regardless whether one searches for the molecular formula of a compound, the pharmacological activity of a compound, or the English name of a plant, the information in the book can be retrieved in multiple ways.
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