Monoamine Oxidases And Their Inhibitors,100, Youdim, Moussa
Автор: Binda Название: Monoamine Oxidase ISBN: 1071626426 ISBN-13(EAN): 9781071626429 Издательство: Springer Рейтинг: Цена: 13415.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This detailed book examines the main methods to study mammalian monoamine oxidases (MAOs), ranging from cell biology to computational chemistry. Beginning with techniques on how to obtain pure samples of MAO A and MAO B, the volume continues by covering assays and techniques used to measure MAO enzymatic activity and perform inhibition studies, methods to address cellular localization and function of MAOs, either in cell lines or in animal models, as well as computational methods applied to rational drug design approaches that are used to develop new MAO inhibitors. Written for the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Monoamine Oxidase: Methods and Protocols serves as a vital resource for scientists who are interested in studying MAOs and other similar amine oxidase enzymes.
Автор: Lars Oreland; Brian A. Callingham Название: Monoamine Oxidase Enzymes ISBN: 3211819851 ISBN-13(EAN): 9783211819852 Издательство: Springer Рейтинг: Цена: 11398.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The papers in this volume are the invited lectures at the Second Workshop on Amine Oxidases held at the Biomedical Center, Uppsala University, 2 to 4 August 1986.
Автор: K.F. Tipton; M.B.H. Youdim; C.J. Barwell; B.A. Cal Название: Amine Oxidases: Function and Dysfunction ISBN: 3211825215 ISBN-13(EAN): 9783211825211 Издательство: Springer Рейтинг: Цена: 10610.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Monoamine oxidase plays a major role in the pathogenesis of neuropsychiatric disorders including depressive illness, Parkinson`s disease and Alzheimer`s disease. The new generation of selective monoamine oxidase inhibitors, devoid of major side effects, has found a prominent place in the treatment of these diseases.
Автор: Satya Prakash Gupta Название: Ion Channels and Their Inhibitors ISBN: 364244282X ISBN-13(EAN): 9783642442827 Издательство: Springer Рейтинг: Цена: 13677.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The present book compiles important chapters authored by eminent workers in the field to cover important recent advances in the studies of the structure and functions of ion channels and their inhibitors, such as sodium ion, potassium ion, chloride ion, calcium ion channel inhibitors.
Описание: It chiefly focuses on the emerging targets of HDACs and their implications for various neurological disorders, while also discussing the drawbacks of current therapeutic strategies, the classification of HDAC inhibitors, and their promising effects in connection with specific neurological disorders.
Автор: Ghani, Usman Название: Alpha-Glucosidase Inhibitors ISBN: 0081027796 ISBN-13(EAN): 9780081027790 Издательство: Elsevier Science Рейтинг: Цена: 29476.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Alpha-glucosidase Inhibitors: Clinically Promising Candidates for Anti-diabetic Drug Discovery presents information that researchers can use to address a whole host of promising leads for the development of novel, oral, anti-diabetic drugs with improved efficacy and fewer side effects. Beginning with a discussion of the huge potential of α -glucosidase inhibitor leads and adaptations, and highlighting their importance within the field of anti-diabetic drug discovery, the book provides chemical structures, detailed background information and in vivo and in vitro biological activity data, and more economical adaptations of these structures.
Drawing on the author's expert research in the field, this book highlights promising leads for development and helps researchers select the most appropriate inhibitors for their own work. It is a useful tool not only for anti-diabetic drug development researchers, but also for those whose research may be enhanced by an understanding of α -glucosidase inhibitor chemistry and activity.
Автор: Michel Pairet; Joanne van Ryn Название: COX-2 Inhibitors ISBN: 3034896077 ISBN-13(EAN): 9783034896078 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field.
Автор: G. Strube Название: ACE Inhibitors in Hypertension ISBN: 9401057370 ISBN-13(EAN): 9789401057370 Издательство: Springer Рейтинг: Цена: 6097.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The treatment of hypertension has progressed in stages following the development of a succession of increasingly effective drugs, each allowing a greater proportion of patients to be treated with fewer and fewer side-effects.
Автор: Sir John R. Vane; Jack H. Botting; R.M. Botting Название: Improved Non-Steroid Anti-Inflammatory Drugs: COX-2 Enzyme Inhibitors ISBN: 9401090319 ISBN-13(EAN): 9789401090315 Издательство: Springer Рейтинг: Цена: 13415.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Thus the anti-inflammatory actions of non-steroid anti-inflammatory drugs (NSAIDs) may be due to the inhibition of COX-2, whereas the unwanted side-effects such as irritation of the stomach lining and toxic effects on the kidney are due to inhibition of the constitutive enzyme, COX-I.
Автор: Paul R. Sanberg; Hitoo Nishino; Cesario V. Borlong Название: Mitochondrial Inhibitors and Neurodegenerative Disorders ISBN: 089603805X ISBN-13(EAN): 9780896038059 Издательство: Springer Рейтинг: Цена: 30370.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Believed to be the remnants of bacterial infection of eukaryotic cells eons ago, the mitochondrion evolved a symbiotic relationship in which it dutifully served as the efficient source of A TP for cell function.
Автор: D.M. Aviado; W.C. Bowman; Geoffrey Burnstock; J. G Название: Adrenergic Activators and Inhibitors ISBN: 3642675867 ISBN-13(EAN): 9783642675867 Издательство: Springer Рейтинг: Цена: 14818.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
