The definitive textbook on the chemical analysis of pharmaceutical drugs - fully revised and updated
Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products and drug substances in biological fluids. A unique emphasis on pharmaceutical laboratory practices, such as sample preparation and separation techniques, provides an efficient and practical educational framework for undergraduate studies in areas such as pharmaceutical sciences, analytical chemistry and forensic analysis. Suitable for foundational courses, this essential undergraduate text introduces the common analytical methods used in quantitative and qualitative chemical analysis of pharmaceuticals.
This extensively revised second edition includes a new chapter on chemical analysis of biopharmaceuticals, which includes discussions on identification, purity testing and assay of peptide and protein-based formulations. Also new to this edition are improved colour illustrations and tables, a streamlined chapter structure and text revised for increased clarity and comprehension.
Introduces the fundamental concepts of pharmaceutical analytical chemistry and statistics
Presents a systematic investigation of pharmaceutical applications absent from other textbooks on the subject
Examines various analytical techniques commonly used in pharmaceutical laboratories
Provides practice problems, up-to-date practical examples and detailed illustrations
Includes updated content aligned with the current European and United States Pharmacopeia regulations and guidelines
Covering the analytical techniques and concepts necessary for pharmaceutical analytical chemistry, Introduction to Pharmaceutical Analytical Chemistry is ideally suited for students of chemical and pharmaceutical sciences as well as analytical chemists transitioning into the field of pharmaceutical analytical chemistry.
Àâòîð: Gary D Christian, Purnendu K. Dasgupta, Kevin A. Schug Íàçâàíèå: Analytical Chemistry, 7th Edition ISBN: 0470887575 ISBN-13(EAN): 9780470887578 Èçäàòåëüñòâî: Wiley Ðåéòèíã: Öåíà: 52844.00 ð. Íàëè÷èå íà ñêëàäå: Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå: The 7 th Edition of Gary Christian`s Analytical Chemistry focuses on more in-depth coverage and information about Quantitative Analysis (aka Analytical Chemistry) and related fields.
A comprehensive introduction for scientists engaged in new drug development, analysis, and approvals
Each year the pharmaceutical industry worldwide recruits thousands of recent science graduates--especially chemistry, analytical chemistry, pharmacy, and pharmaceutical majors--into its ranks. However, because of their limited background in pharmaceutical analysis most of those new recruits find making the transition from academia to industry very difficult. Designed to assist both recent graduates, as well as experienced chemists or scientists with limited regulatory, compendial or pharmaceutical analysis background, make that transition, Pharmaceutical Analysis for Small Molecules is a concise, yet comprehensive introduction to the drug development process and analysis of chemically synthesized, small molecule drugs. It features contributions by distinguished experts in the field, including editor and author, Dr. Behnam Davani, an analytical chemist with decades of technical management and teaching experience in compendial, regulatory, and industry.
This book provides an introduction to pharmaceutical analysis for small molecules (non-biologics) using commonly used techniques for drug characterization and performance tests. The driving force for industry to perform pharmaceutical analyses is submission of such data and supporting documents to regulatory bodies for drug approval in order to market their products. In addition, related required supporting studies including good laboratory/documentation practices including analytical instrument qualification are highlighted in this book.
Topics covered include:
Drug Approval Process and Regulatory Requirements (private standards)
Pharmacopeias and Compendial Approval Process (public standards)
Common methods in pharmaceutical analysis (typically compendial)
Common Calculations for assays and impurities and other specific tests
Analytical Method Validation, Verification, Transfer
Specifications including how to handle out of specification (OOS) and out of trend (OOT)
Impurities including organic, inorganic, residual solvents and elemental impurities
Good Documentation Practices for regulatory environment
Management of Analytical Laboratories
Analytical Instrument Qualifications including IQ, OQ, PQ and VQ
Due to global nature of pharmaceutical industry, other topics on both regulatory (ICH) and Compendial harmonization are also highlighted.
Pharmaceutical Analysis for SmallMolecules is a valuable working resource for scientists directly or indirectly involved with the drug development process, including analytical chemists, pharmaceutical scientists, pharmacists, and quality control/quality assurance professionals. It also is an excellent text/reference for graduate students in analytical chemistry, pharmacy, pharmaceutical and regulatory sciences.
Îïèñàíèå: This book provides a detailed overview of the fundamental principles and methods of spectroscopy and photochemical modeling for studying the chemical composition of planetary atmospheres and ionospheres. With detailed reviews of Mars, Venus, Titan, Triton and Pluto, it is a valuable reference for graduate students, researchers and planetary scientists.
Îïèñàíèå: Analytical Chemistry: A Practical Approach is the only chemical analysis text with an emphasis on active learning, giving students step-by-step guidance on how the key principles of analytical science are applied in a range of practical, real-world contexts.
Àâòîð: Oluwatosin Ademola Ijabadeniyi Íàçâàíèå: Food Science and Technology: Trends and Future Prospects ISBN: 3110667452 ISBN-13(EAN): 9783110667455 Èçäàòåëüñòâî: Walter de Gruyter Öåíà: 14342.00 ð. Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå:
Food Science and Technology: Trends and Future Prospects presents different aspects of food science i.e., food microbiology, food chemistry, nutrition, process engineering that should be applied for selection, preservation, processing, packaging, and distribution of quality food. The authors focus on the fundamental aspects of food and also highlight emerging technology and innovations that are changing the food industry. The chapters are written by leading researchers, lecturers, and experts in food chemistry, food microbiology, biotechnology, nutrition, and management. This book is valuable for researchers and students in food science and technology and it is also useful for food industry professionals, food entrepreneurs, and farmers.
Àâòîð: Sifang Li Íàçâàíèå: Manufacture of Fine Chemicals from Acetylene ISBN: 3110714965 ISBN-13(EAN): 9783110714968 Èçäàòåëüñòâî: Walter de Gruyter Ðåéòèíã: Öåíà: 26954.00 ð. Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå:
The book gives a complete overview on today’s research, development and industrialization of fine chemicals from acetylene. The author provides a comprehensive methodology by covering derivatives from acetylene reacting with formaldehyde, alcohol, ketone, halogen and acetic acid.
The book offers extensive and practical reference work for chemists and chemical engineers as well as university teachers and students.
Àâòîð: Ibar Jean Pierre Íàçâàíèå: Dual-Phase Depolarization Analysis ISBN: 3110756692 ISBN-13(EAN): 9783110756692 Èçäàòåëüñòâî: Walter de Gruyter Ðåéòèíã: Öåíà: 36252.00 ð. Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå:
This book focuses on the characterization of the amorphous phase of polymers, whether they are pure amorphous or semi-crystalline ones, above Tg or below Tg, by studying the relaxation of dipoles and space charges naturally found in their structure after they have been activated by the application of a voltage field. The experimental deconvolution of the relaxation modes responsible for internal motion in the amorphous phase is coupled with a mathematical procedure (Thermal-Windowing Deconvolution-TWD) that leads to the understanding of their coupling characteristics which, it is shown, relate to the state of the material itself, for instance its non-equilibrium state or its internal stress for matter belonging to interfaces between aggregated or dispersed phases.
Describes quantitatively the Thermal Stimulated Depolarization techniques of polymer characterization (TSD, TWD), i.e. how to decouple the relaxation modes collectively interacting (interactive coupling) and relate it to the thermodynamic properties of the amorphous phase.
Understands the results of depolarization in terms of the new physics of polymer interactions: the Dual-Phase model, here applied to the dipoles-space charge dynamics.
Provides a roaster of CASE STUDIES: practical applications of the TSD and TWD characterization techniques to describe coupled molecular motions in resins, medical tissues, wood, blends and block copolymers interfaces, rubbers, can coatings, internal stress in molded parts, etc
Àâòîð: Hsu Chang Samuel Íàçâàíèå: Analytical Advances for Hydrocarbon Research ISBN: 030647476X ISBN-13(EAN): 9780306474767 Èçäàòåëüñòâî: Springer Ðåéòèíã: Öåíà: 15855.00 ð. Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå: Determining the composition and properties of complex hydrocarbon mixtures in petroleum, synthetic fuels, and petrochemical products usually requires a battery of analytical techniques that detect and measure specific features of the molecules, such as boiling point, mass, nuclear magnetic resonance frequencies, etc. there have always been a need for new and improved analytical technology to better understand hydrocarbon chemistry and processes. This book provides an overview of recent advances and future challenges in modern analytical techniques that are commonly used in hydrocarbon applications. Experts in each of the areas covered have reviewed the state of the art, thus creating a book that will be useful to readers at all levels in academic, industry, and research institutions.
Àâòîð: Ellison Stephen Íàçâàíèå: Practical Statistics for the Analytical Scientist ISBN: 0854041311 ISBN-13(EAN): 9780854041312 Èçäàòåëüñòâî: Royal Society of Chemistry Ðåéòèíã: Öåíà: 4744.00 ð. Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå: This book will be welcomed by practising analytical chemists as an important reference for day to day statistics in analytical chemistry.
Àâòîð: Qian Íàçâàíèå: Electrokinetic Particle Transport in Micro-/Nanofluidics ISBN: 1439854386 ISBN-13(EAN): 9781439854389 Èçäàòåëüñòâî: Taylor&Francis Ðåéòèíã: Öåíà: 26030.00 ð. Íàëè÷èå íà ñêëàäå: Åñòü ó ïîñòàâùèêà Ïîñòàâêà ïîä çàêàç.
Îïèñàíèå:
Numerous applications of micro-/nanofluidics are related to particle transport in micro-/nanoscale channels, and electrokinetics has proved to be one of the most promising tools to manipulate particles in micro/nanofluidics. Therefore, a comprehensive understanding of electrokinetic particle transport in micro-/nanoscale channels is crucial to the development of micro-/nanofluidic devices.
Electrokinetic Particle Transport in Micro-/Nanofluidics: Direct Numerical Simulation Analysis provides a fundamental understanding of electrokinetic particle transport in micro-/nanofluidics involving electrophoresis, dielectrophoresis, electroosmosis, and induced-charge electroosmosis. The book emphasizes the direct numerical simulation of electrokinetic particle transport phenomena, plus several supportive experimental studies. Using the commercial finite element package COMSOL Multiphysics(R), it guides researchers on how to predict the particle transport subjected to electric fields in micro-/nanoscale channels.
Researchers in the micro-/nanofluidics community, who may have limited experience in writing their own codes for numerical simulations, can extend the numerical models and codes presented in this book to their own research and guide the development of real micro-/nanofluidics devices.
Corresponding COMSOL(R) script files are provided with the book and can be downloaded from the author's website.
Îïèñàíèå: Gas chromatography mass spectrometry (GC-MS) has been the technique of choice of analytical scientists for many years. This book summarizes the major advances and relevant applications of GC-MS techniques over the years, with chapters by leading authors in the field of environmental chemistry.
