Virtual Screening And Drug Docking,59, Caballero, Julio
Автор: N.S. Parmar , Shiv Prakash Название: Screening Methods in Pharmacology ISBN: 1842653466 ISBN-13(EAN): 9781842653463 Издательство: Alpha Science Цена: 6000.00 р. 8571.00-30% Наличие на складе: Есть (1 шт.) Описание: Provides a concise account of in vivo methods used in the pharmacological screening of important categories of clinically useful drugs. This book encompasses the basic principles of animal experimentation and current advances leading to the use of transgenic animals, combinatorial chemistry, pharmacogenomics, proteomics and array technology.
Автор: Martins Название: G Protein-Coupled Receptor Screening Assays ISBN: 1071612239 ISBN-13(EAN): 9781071612231 Издательство: Springer Рейтинг: Цена: 14635.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This fully updated edition targets not only those assays directly involved in the discovery of GPCR-active compounds but also those involved in cell-based experiments designed to study physiological responses. Whether coming from academia or industry, or being an experienced researcher or a newcomer to the field, the reader will find accessible methods and protocols that cover the latest developments on receptor purification, molecular biology, recombinant engineering, and analytical techniques that enable the real time monitoring of the complex GPCR signaling cascade and identification of potential drug targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, G Protein-Coupled Receptor Screening Assays: Methods and Protocols, Second Edition aims to provide the tools necessary to contribute to the advancement of GPCR research and discovery and ultimately lead to the availability of innovative and more efficient drugs.
Автор: Zhu, Hao Название: High-throughput screening assays in toxicology ISBN: 1493981714 ISBN-13(EAN): 9781493981717 Издательство: Springer Рейтинг: Цена: 11586.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on recently developed High Throughput Screening (HTS) assay protocols, many involved in the ToxCast and/or Tox21 initiatives, and the relevant HTS data analysis techniques. Divided into three sections, in vitro assays, in vivo assays, and computational techniques to analyze HTS data are all examined. Written for the highly successful Methods in Molecular Biology series, most chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High Throughput Screening Assays in Toxicology serves as a valuable reference resource for translating new HTS techniques into standardized chemical toxicity assessment tools in order to advance modern toxicology research to a new era where HTS techniques can partially replace the prevailing animal models.
Автор: Michael Kahn Название: High Throughput Screening for Novel Anti-Inflammatories ISBN: 303489578X ISBN-13(EAN): 9783034895781 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Combinatorial chemistry in conjunction with High Throughput Screening (HTS) is revolutionizing the drug discovery process.
Автор: Dastmalchi Siavoush, Hamzeh-Mivehroud Maryam, Sokouti Babak Название: Applied Case Studies and Solutions in Molecular Docking-Based Drug Design ISBN: 1522503625 ISBN-13(EAN): 9781522503620 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 28215.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As the pharmaceutical industry continues to advance, new techniques in drug design are emerging. In order to deliver optimum care to patients, the development of innovative pharmacological techniques has become a widely studied topic.Applied Case Studies and Solutions in Molecular Docking-Based Drug Design is a pivotal reference source for the latest scholarly research on the progress of pharmaceutical design and computational approaches in the field of molecular docking. Highlighting innovative research perspectives and real-world applications, this book is ideally designed for professionals, researchers, practitioners, and medical chemists actively involved in computational chemistry and pharmaceutical sciences.
Автор: Dastmalchi Siavoush, Hamzeh-Mivehroud Maryam, Sokouti Babak Название: Methods and Algorithms for Molecular Docking-Based Drug Design and Discovery ISBN: 1522501150 ISBN-13(EAN): 9781522501152 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 40128.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As the pharmaceutical industry continues to advance, new techniques in drug design are emerging. In order to deliver optimal care to patients, the development of innovative pharmacological techniques has become a widely studied topic.The Handbook of Research on Molecular Docking-Based Drug Design and Discovery investigates the evolution of pharmaceutical design and computational approaches in the field of molecular docking. Highlighting theoretical backgrounds and emergent research in the area of computer-assisted drug design, this publication is a pivotal source for professionals, researchers, medical chemists, pharmaceutical experts, and students interested in innovative practices and findings within the fields of computational chemistry and pharmaceutical sciences.
Автор: S. Mohane Coumar Название: Molecular docking for computer-aided drug design ISBN: 012822312X ISBN-13(EAN): 9780128223123 Издательство: Elsevier Science Рейтинг: Цена: 16161.00 р. Наличие на складе: Нет в наличии.
Описание: Collins Explore English is a 6-level course which provides full coverage of the Cambridge Primary English as a Second Language curriculum framework (0057) from 2020. With a magazine-style Student`s Resource Book, comprehensive Student`s Coursebook, and supportive Teacher`s Guide, it offers clear progression within and across levels.
Автор: Walter Filgueira de Azevedo Jr. Название: Docking Screens for Drug Discovery ISBN: 1493997548 ISBN-13(EAN): 9781493997541 Издательство: Springer Рейтинг: Цена: 14635.00 р. Наличие на складе: Нет в наличии.
Автор: Baker Judith Название: Virtual Screening: Methods and Techniques ISBN: 1632424258 ISBN-13(EAN): 9781632424259 Издательство: Неизвестно Цена: 13679.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Beverly A. Teicher; Paul A. Andrews Название: Anticancer Drug Development Guide ISBN: 146849841X ISBN-13(EAN): 9781468498417 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of "antileukemia" agents, but that other tumor models would be needed to discover drugs active against solid tumors.
Автор: Beverly A. Teicher Название: Anticancer Drug Development Guide ISBN: 1461581540 ISBN-13(EAN): 9781461581543 Издательство: Springer Рейтинг: Цена: 14818.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Experienced cancer researchers from pharmaceutical companies, government laboratories, and academia comprehensively review and describe the arduous process of cancer drug discovery and approval.
Автор: Teicher Название: Anticancer Drug Development Guide. 2ed.2004 ISBN: 1588292282 ISBN-13(EAN): 9781588292285 Издательство: Springer Рейтинг: Цена: 30370.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This thoroughly updated and expanded second edition of Beverly Teicher's widely used classic survey provides a step-by-step guide to anticancer drug development from initial design through FDA approval. The authors have included new material on the use of high throughput screening in industry, on specialized in vitro/in vivo procedures employed by the National Cancer Institute (NCI) in preclinical drug evaluations, and on nonclinical testing to support both human clinical trials, as well as trials of biologic oncology products. The chapters on phase I, II, and III clinical trials and on novel phase II clinical trial designs for targeted therapies have been significantly updated, along with those on cancer drug development in Europe, working with the NCI, and the FDA's role in cancer drug development and setting requirements for approval.
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