Genome Editing in Cardiovascular and Metabolic Diseases, Xiao
Автор: Maria P. Abracchio; Michael Williams Название: Purinergic and Pyrimidinergic Signalling II ISBN: 3642632238 ISBN-13(EAN): 9783642632235 Издательство: Springer Рейтинг: Цена: 34150.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Gopalan Название: Biology Of Cardiovascular And Metabolic Disease ISBN: 0128234210 ISBN-13(EAN): 9780128234211 Издательство: Elsevier Science Рейтинг: Цена: 19370.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Biology of Cardiovascular and Metabolic Diseases combines physiology and pathophysiology of selected metabolic and cardiovascular diseases that is of health relevance. Written in a concise and easy to read manner, the book allows readers to gain an understanding on a number of topics, including cardiovascular physiology and pathophysiology and how it relates to the development of insulin resistance, diabetes, and other metabolic diseases. The book also highlights the relevance of obesity in the development of cardiovascular and metabolic diseases and emphasizes the benefits of exercise as a preventative measure as well as a way to treat an underlying condition.
Автор: Papageorgiou, Nikolaos Название: Cardiovascular Diseases ISBN: 0128033126 ISBN-13(EAN): 9780128033128 Издательство: Elsevier Science Рейтинг: Цена: 17517.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors and Their Interaction covers the special heritability characteristics and identifying genetic and environmental contributions to cardiovascular health. This important reference provides an overview of the genetic basis of cardiovascular disease and its risk factors. Included are important topics, ranging from lifestyle choices, risk factors, and exposure, to pollutants and chemicals. Also covered are the influences of Mendelian traits and familial aggregation and the interactions and interrelationships between genetics and environmental factors which, when compared, provide a sound understanding of the interplay between inherited and acquired risk factors. The book provides a much needed reference for this rapidly growing field of study. By combining the latest research within the structured chapters of this reference, a better understanding of genetic and environmental contribution to cardiovascular disease is found, helping to substantiate further investigations in the field and design prevention and treatment strategies.
Автор: Junjie Xiao; Sanda Cretoiu Название: Exosomes in Cardiovascular Diseases ISBN: 9811043965 ISBN-13(EAN): 9789811043963 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized.
Автор: Ishikawa Название: Experimental Models of Cardiovascular Diseases ISBN: 1493985965 ISBN-13(EAN): 9781493985968 Издательство: Springer Рейтинг: Цена: 13415.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Part I: Overview
1. Experimental Models of Cardiovascular Diseases - Overview -
Jae Gyun Oh and Kiyotake Ishikawa
Part II: In Silico Models
2. An Introduction to Computational Modeling of Cardiac Electrophysiology and Arrhythmogenicity
Joshua Mayourian, Eric A. Sobie, and Kevin D. Costa
Part III: In Vitro Models
3. Isolation of Atrial and Ventricular Cardiomyocytes for In Vitro Studies
Jelena Plačkic and Jens Kockskдmper
4. Cardiomyocyte Differentiation from mouse Embryonic Stem Cells
Adam T Lynch, Silvia Mazzotta, and Stefan Hoppler
5. Cardiomyocyte Differentiation from Human Embryonic Stem Cells
Silvia Mazzotta, Adam T Lynch, and Stefan Hoppler
6. Induction of Human Induced Pluripotent Stem Cells to Cardiomyocytes using Embryoid Bodies
Takeshi Hatani1, Kenji Miki, and Yoshinori Yoshida
7. Measuring Cardiomyocyte Contractility and Calcium Handling In Vitro
Przemek A. Gorski, Changwon Kho, and Jae Gyun Oh
Part IV: Ex Vivo Models
8. Langendorff Perfusion Method as an Ex Vivo Model to Evaluate Heart Function in Rats
Makino Watanabe and Takao Okada
9. Methods for the Preparation of an Excised, Cross-circulated Rat Heart
Koji Obata and Miyako Takaki
10. Optical Action Potential Mapping in Acute Models of Ischemia-reperfusion Injury: Probing the Arrhythmogenic Role of the Mitochondrial Translocator Protein
Zeki Ilkan, Benjamin Strauss, Chiara Campana, and Fadi G. Akar
11. Cardiac Tissue Engineering Models of Inherited and Acquired Cardiomyopathies
Irene C. Turnbull, Joshua Mayourian, Jack F. Murphy, Francesca Stillitano,
Delaine K. Ceholski, and Kevin D. Costa
12. Badimon Perfusion Chamber: An Ex Vivo Model of Thrombosis
M. Urooj Zafar, Carlos G. Santos-Gallego, Lina Badimon, and Juan J. Badimon,
Part V: Small Animal Models
13. Ischemic Model of Heart Failure in Rats and Mice
Jiqiu Chen, Delaine K. Ceholski, Irene C. Turnbull, Lifan Liang, and Roger J. Hajjar
14. Conventional Method of Transverse Aortic Constriction in Mice
Jimeen Yoo, Vadim Chepurko, Roger J. Hajjar, and Dongtak Jeong
15. &nbs
Название: Exosomes in cardiovascular diseases ISBN: 9811351279 ISBN-13(EAN): 9789811351273 Издательство: Springer Рейтинг: Цена: 13415.00 р. Наличие на складе: Нет в наличии.
Описание: The book provides and intensive overview on exosomes in cardiovascular diseases, its potential as biomarkers, as well as pathological and therapeutic effects. Secondly, basic aspects of exosomes including the purification methods of exosomes, exosomes content, and functional roles of the cardiovascular exosomes are summarized.
Автор: Xiao Junjie Название: Non-Coding Rnas in Cardiovascular Diseases ISBN: 9811516707 ISBN-13(EAN): 9789811516702 Издательство: Springer Цена: 18294.00 р. Наличие на складе: Нет в наличии.
Описание: The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding RNAs and cardiovascular diseases, 5) Potential biomarkers and therapeutic implications, 6) Future prospects.
Автор: Xiao Junjie Название: Non-Coding Rnas in Cardiovascular Diseases ISBN: 9811516731 ISBN-13(EAN): 9789811516733 Издательство: Springer Цена: 18294.00 р. Наличие на складе: Нет в наличии.
Описание: The book consists of six parts: 1) An overview of non-coding RNAs and cardiovascular system, 2) Bioinformatics and interactions, 3) Non-coding RNA regulation in cardiovascular system, 4) Non-coding RNAs and cardiovascular diseases, 5) Potential biomarkers and therapeutic implications, 6) Future prospects.
Описание: The CRISPR-Cas9 genome-editing system is creating a revolution in the science world. In the laboratory, CRISPR-Cas9 can efficiently be used to target specific genes, correct mutations and regulate gene expression of a wide array of cells and organisms, including human cells.
Автор: Jean-Marie Saudubray; Matthias R. Baumgartner; Joh Название: Inborn Metabolic Diseases ISBN: 3662497697 ISBN-13(EAN): 9783662497692 Издательство: Springer Рейтинг: Цена: 21953.00 р. Наличие на складе: Нет в наличии.
Описание: This work is recognised as the standard textbook for professionals involved in the diagnosis and management of inborn errors of metabolism (IEM) and an essential resource in this multidisciplinary field. For the 6th edition all 43 chapters have been newly written or revised by authors with particular expertise in their subject areas. Contents: A clinical and biochemical approach to the recognition and diagnosis of IEM with algorithms to symptoms, signs, and syndromes in patients of all ages; Emergency treatments; Medications – Separate comprehensive sections on IEM of: Carbohydrates; Mitochondrial Energy; Amino and organic acids; Vitamin-responsive defects; Neurotransmitter and Small peptides, Lipid and Bile Acids; Nucleic Acid and Heme; Organelles – Disorders affecting the synthesis and remodelling of complex lipids and fatty acid homeostasis are now included.
Автор: Kuete, Victor Название: Medicinal Spices and Vegetables from Africa ISBN: 0128092866 ISBN-13(EAN): 9780128092866 Издательство: Elsevier Science Рейтинг: Цена: 18696.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Medicinal Spices and Vegetables from Africa: Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases provides a detailed look at medicinal spices and vegetables that have proven safe-and-effective for consumption and the treatment of diseases, including infectious diseases, cardiovascular disease, and cancer.
It provides pharmacological evidence, such as the latest information related to efficacy and safety data, in vitro and in vivo studies, clinical trials, and more, to illustrate the use of these spices and vegetables as both palliative and alternative treatments with the goal of furthering research in this area to produce safer and more effective drugs.
Описание: It is a pleasure to introduce this new book, Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional, and Deposition Disease, edited by two of my friends and respected colleagues, Franco Rongioletti and Bruce R. Smoller. In fact, I was very ent- siastic when I learned that they were preparing this work. Although endocrine, metabolic, w, and deposition diseases are regularly included in general textbooks of dermatology and d- matopathology, one gains the general impression that these topics receive little emphasis and are mainly included for completeness. The prospect of having all of this information in one volume, lovingly described and detailed by experts in the feld, should be of great interest not only to dermatologists, pathologists, and dermatopathologists but also to internists and en- crinologists, who may well gain a different perspective on these disorders. As a derma- pathologist, I am also pleased that this project has been organized and undertaken by two distinguished authorities in cutaneous pathology. This assures a close integration of histo- thology and other laboratory techniques with the clinical aspects of these disorders, which will make it possible – perhaps for the frst time – to view these conditions in a truly comprehensive way. So I invite you, the reader, to open this volume and dig in; be prepared for an eye-catching, intellectually stimulating, and ultimately rewarding experience! Charlottesville, VA James W. Patterson v w Foreword II Dermatopathology is a bridge between Dermatology and Pathology.
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