Название: Handbook of Cell-Penetrating Peptides ISBN: 0367390485 ISBN-13(EAN): 9780367390488 Издательство: Taylor&Francis Рейтинг: Цена: 10411.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of new information on the use of these peptides as transport systems has in fact served to confound the field. The constant internal change in the field of cell-penetrating peptides (CPPs) is due to recent research uncovering apparent ambiguities in cellular uptake. There is still neither a common terminology nor a uniform explanation for the penetrative mechanism of cell-penetrating peptides.
In this second edition of the Handbook of Cell-Penetrating Peptides, the authors summarize the current state of the field including recent reevaluations of earlier studies of CPP mechanisms. Beginning with an overview of the classes of peptides and their individual uptake mechanisms, from the earlier lipid models to the more recent endocytotic pathways, the book demonstrates the diversity and the opportunity for these biologically active proteins to serve as future drug leads. The text then covers the use of CPPs in gene modulation, addressing the application of antisense and decoy oligonucleotides, as well as the new avenue of research targeting specific tumors and other tissues-questions that had barely been asked when the first edition was published. By summarizing the diffuse information regarding CPPs, including the ambiguities and variety of mechanisms, the Handbook of Cell-Penetrating Peptides provides the most solid foundation available from which to expand the potential of this rapidly growing field of medicine.
Автор: Langel Название: Handbook of Cell-Penetrating Peptides, Second Edition ISBN: 0849350905 ISBN-13(EAN): 9780849350900 Издательство: Taylor&Francis Рейтинг: Цена: 43639.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Summarizes the state of the peptides field including reevaluations of earlier studies of cell-penetrating peptides (CPP) mechanisms. Offering an overview of the classes of peptides and their individual uptake mechanisms, this book covers the use of CPPs in gene modulation, and the targeting of specific tumors and other tissues.
Автор: Langel Ьlo Название: Cell Penetrating Peptides: Methods and Protocols ISBN: 1071617516 ISBN-13(EAN): 9781071617519 Издательство: Springer Рейтинг: Цена: 21953.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This third edition summarizes the most important areas of Cell-Penetrating Peptides (CPP) research. Chapters are divided into three parts detailing the historical background of CPP, the classifications of the available CPPs, approaches for prediction of novel CPPs, methods for studies of “naked” CPPs, and a brief summary of functionality issues of CPPs, both in vitro and in vivo. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and cutting-edge, Cell Penetrating Peptides: Methods and Protocols, Third Edition aims to be a useful practical guide to researches to help further their study in this field.
Автор: Willis K. Samson; Ellis Levin Название: Natriuretic Peptides in Health and Disease ISBN: 1461284414 ISBN-13(EAN): 9781461284413 Издательство: Springer Рейтинг: Цена: 22797.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A comprehensive, state-of-the-art review of the biochemistry, molecular and cellular biology, pharmacology, physiology, and pathology of natriuretic peptides.
Автор: Dietmar Richter Название: Regulatory Peptides and Cognate Receptors ISBN: 3662129086 ISBN-13(EAN): 9783662129081 Издательство: Springer Рейтинг: Цена: 24392.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the last two decades, our knowledge on regulatory peptides and their cognate receptors, most of which are members of the seven transmembrane receptor families, has increased enormously. Regulatory peptides are small proteins which, besides their hormonal functions in regulating cellular metabolism in various tissues, may also act as neurotransmitters, and thus they often carry the prefix "neuro". Many of the cognate receptors involved in transducing the peptidergic signal across the cell membrane via a family of G proteins exist in multiple forms, the number of which frequently exceeds that of the corresponding peptide ligands. In this book, various peptide-receptor systems are discussed, e.g. CRF, somatostatin, TRH, opioid peptides, vasopressin, and oxytocin. It also discusses new strategies such as "reverse physiology" to uncover new peptides and orphan receptors.
Автор: Dietmar Richter Название: Regulatory Peptides and Cognate Receptors ISBN: 3540653252 ISBN-13(EAN): 9783540653257 Издательство: Springer Рейтинг: Цена: 38908.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Since the 1980s, our knowledge of regulatory peptides and their cognate receptors has greatly increased. This text discusses various peptide receptor systems, for example CRF, somatostatin, TRH, opioid peptides and vasopressin, and strategies for uncovering new peptides are examined.
Автор: Said, Sami I. Название: Proinflammatory and Antiinflammatory Peptides ISBN: 0824701208 ISBN-13(EAN): 9780824701208 Издательство: Taylor&Francis Рейтинг: Цена: 35218.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focusing on signaling in pollen tube integrity and sperm release regulation, it provides significant insights into the BUPS-ANX receptor complex and the corresponding ligands RALF4/19 to promote pollen tube growth with proper cell integrity.
Автор: Johann C. R?egg Название: Peptides as Probes in Muscle Research ISBN: 3642764118 ISBN-13(EAN): 9783642764110 Издательство: Springer Рейтинг: Цена: 13415.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Protein-protein interactions are involved in muscle contraction and signal transduction. These timely contributions by several experts will appeal to the researchers in muscle physiology, cardiovascular pharmacology and cell biology who are interested in this new approach.
Автор: Weiner, David B. Williams, William V. Название: Biologically active peptides ISBN: 0877629358 ISBN-13(EAN): 9780877629351 Издательство: Taylor&Francis Рейтинг: Цена: 33686.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Investigation into basic and advanced peptide design, synthesis, evaluation and utilization
Описание: Focusing on signaling in pollen tube integrity and sperm release regulation, it provides significant insights into the BUPS-ANX receptor complex and the corresponding ligands RALF4/19 to promote pollen tube growth with proper cell integrity.
Автор: Langel, Ulo , Cravatt, Benjamin F. , Graslund, A Название: Introduction to Peptides and Proteins ISBN: 0367384876 ISBN-13(EAN): 9780367384876 Издательство: Taylor&Francis Рейтинг: Цена: 10411.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Human cells produce at least 30,000 different proteins. Each has a specific function characterized by a unique sequence and native conformation that allows it to perform that function. While research in this post-genomic era has created a deluge of invaluable information, the field has lacked for an authoritative introductory text needed to inform researchers and students in all of those fields now concerned with protein research.
Introduction to Peptides and Proteins brings together some of the most respected researchers in protein science to present a remarkably coherent introduction to modern peptide and protein chemistry. The first sections of the book delve into -
Basic peptide and protein science from assembly through degradation
Traditional and emerging research methods including those used in bioinformatics and proteomics
New computational approaches and algorithms used to find patterns in the vast data collected by sequencing projects
After providing a foundation in tools and methods, the authors closely examine six protein families, including representative classes such as enzymes, cell-surface receptors, antibodies, fibrous proteins, and bioactive peptide classes. They concentrate on biochemical mechanisms and where possible indicate therapeutic or biotechnical possibilities.
Then focusing on clinical aspects, the authors investigate misfolding as found in prion diseases, miscleavage as found in Alzheimer's, and mis-sequencing as found with some cancers. Drawing from some of their own research, the authors summarize recent achievements and emerging applications. They discuss the use of proteins and peptides as drugs and the solid-phase synthesis required for drug production. They also look at the use of peptides as functional biomolecules and research tools.
No longer just th
ООО "Логосфера " Тел:+7(495) 980-12-10 www.logobook.ru
