Описание: Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites.
To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.
Описание: This book reviews the state-of-the-art in multiscale computer modeling, examining both its accomplishments and its challenges. Helps connect traditional biomedical engineering at the organ and tissue scale with cellular and molecular bioengineering.
Автор: Gefen Amit Название: Multiscale Computer Modeling in Biomechanics and Biomedical ISBN: 3642364810 ISBN-13(EAN): 9783642364815 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the state-of-the-art in multiscale computer modeling, examining both its accomplishments and its challenges. Helps connect traditional biomedical engineering at the organ and tissue scale with cellular and molecular bioengineering.
Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites.
To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.
Автор: Vikas Tomar; Tao Qu; Devendra K. Dubey; Devendra V Название: Multiscale Characterization of Biological Systems ISBN: 1493934511 ISBN-13(EAN): 9781493934515 Издательство: Springer Рейтинг: Цена: 17074.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book covers the latest research work done in the area of interface mechanics of collagen and chitin-based biomaterials along with various techniques that can be used to understand mechanics of biological systems and materials.
The use of micro / nanotechnology in cell and tissue engineering, and especially for cell and tissue preservation, is at the peak of its activity now, with scientific output expected to continue growing in the coming years.
Micro and nanotechnologies have induced paradigm shifts in many scientific fields, and as featured in this edited volume, they are having important impact in the field of cryomedicine. The book gives an overview of the recent progress in implementing multiscale (micro and nanoscale) technologies to improve the outcome of various cryomedical applications including cryosurgery, cryopreservation, lyopreservation and to understand the fundamental engineering and science underpinning the applications.
This is the first book that will provide both an introductory and in-depth account of applying the multiscale technologies in cryomedicine.
Автор: Suvranu De; Wonmuk Hwang; Ellen Kuhl Название: Multiscale Modeling in Biomechanics and Mechanobiology ISBN: 1447172299 ISBN-13(EAN): 9781447172291 Издательство: Springer Рейтинг: Цена: 13677.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms.
Описание: In Memory of Professor Sergey Grigorievich Psakhie.- Biomechanical and Tribological Aspects of Orthopaedic Implants.- A New Method for Seismically Safe Managing of Seismotectonic Deformations in Fault Zones.- Particle-Based Approach for Simulation of Nonlinear Material Behavior in Contact Zones.- A Tool for Studying the Mechanical Behavior of the Bone-Endoprosthesis System Based on Multi-scale Simulation.- Abstract Methods on Mesoscopic Scales of Friction.- Study of Dynamics of Block-Media in the Framework of Minimalistic Numerical Models.- Material Transfer by Friction Stir Processing.- Nanomaterials Interaction with Cell Membranes: Computer Simulation Studies.- Application of Crumpled Aluminum Hydroxide Nanostructures for Cancer Treatment.- Influence of Lattice Curvature and Nanoscale Mesoscopic Structural States on the Wear Resistance and Fatigue Life of Austenitic Steel.- Autowave Mechanics of Plastic Flow.- Three-Component Wear-Resistant PEEK-Based Composites Filled with PTFE and MoS2: Composition Optimization, Structure Homogenization, and Self-Lubricating Effect.- Regularities of Structural Rearrangements in Single- and Bicrystals Near the Contact Zone.- Fault Sliding Modes - Governing, Evolution and Transformation.- Multilayer Modelling of Lubricated Contacts: A New Approach Based on a Potential Field Description.- Microstructure-Based Computational Analysis of Deformation and Fracture in Composite and Coated Materials Across Multiple Spatial Scales.- Formation of a Nanostructured Hardened Surface Layer on the TiC-(Ni-Cr) Metal-Ceramic Alloy by Pulsed Electron-Beam Irradiation.- Adhesion of a Thin Soft Matter Layer: The Role of Surface Tension.- Adhesion Hysteresis Due to Chemical Heterogeneity.- Theoretical Study of Physico-Mechanical Response of Permeable Fluid-Saturated Materials under Complex Loading Based on the Hybrid Cellular Automaton Method.- Transfer of a Biological Fluid Through a Porous Wall of a Capillary.- Failure Mechanisms of Alloys with a Bimodal Graine Size Distribution.- Self-Reproduction Cycles of Living Matter and Energetics of Human Activity.- Seeing what Lies in Front of Your Eyes: Understanding and Insight in Teaching and Research.
Описание: In Memory of Professor Sergey Grigorievich Psakhie.- Biomechanical and Tribological Aspects of Orthopaedic Implants.- A New Method for Seismically Safe Managing of Seismotectonic Deformations in Fault Zones.- Particle-Based Approach for Simulation of Nonlinear Material Behavior in Contact Zones.- A Tool for Studying the Mechanical Behavior of the Bone-Endoprosthesis System Based on Multi-scale Simulation.- Abstract Methods on Mesoscopic Scales of Friction.- Study of Dynamics of Block-Media in the Framework of Minimalistic Numerical Models.- Material Transfer by Friction Stir Processing.- Nanomaterials Interaction with Cell Membranes: Computer Simulation Studies.- Application of Crumpled Aluminum Hydroxide Nanostructures for Cancer Treatment.- Influence of Lattice Curvature and Nanoscale Mesoscopic Structural States on the Wear Resistance and Fatigue Life of Austenitic Steel.- Autowave Mechanics of Plastic Flow.- Three-Component Wear-Resistant PEEK-Based Composites Filled with PTFE and MoS2: Composition Optimization, Structure Homogenization, and Self-Lubricating Effect.- Regularities of Structural Rearrangements in Single- and Bicrystals Near the Contact Zone.- Fault Sliding Modes - Governing, Evolution and Transformation.- Multilayer Modelling of Lubricated Contacts: A New Approach Based on a Potential Field Description.- Microstructure-Based Computational Analysis of Deformation and Fracture in Composite and Coated Materials Across Multiple Spatial Scales.- Formation of a Nanostructured Hardened Surface Layer on the TiC-(Ni-Cr) Metal-Ceramic Alloy by Pulsed Electron-Beam Irradiation.- Adhesion of a Thin Soft Matter Layer: The Role of Surface Tension.- Adhesion Hysteresis Due to Chemical Heterogeneity.- Theoretical Study of Physico-Mechanical Response of Permeable Fluid-Saturated Materials under Complex Loading Based on the Hybrid Cellular Automaton Method.- Transfer of a Biological Fluid Through a Porous Wall of a Capillary.- Failure Mechanisms of Alloys with a Bimodal Graine Size Distribution.- Self-Reproduction Cycles of Living Matter and Energetics of Human Activity.- Seeing what Lies in Front of Your Eyes: Understanding and Insight in Teaching and Research.
Автор: Damien Lacroix et al Название: Multiscale Mechanobiology in Tissue Engineering ISBN: 9811080747 ISBN-13(EAN): 9789811080746 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level.
Автор: Damien Lacroix; Marzia Brunelli; C?cile Perrault; Название: Multiscale Mechanobiology in Tissue Engineering ISBN: 9811340560 ISBN-13(EAN): 9789811340567 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.
Автор: Chauvi?re, Arnaud Название: Cell Mechanics ISBN: 1420094548 ISBN-13(EAN): 9781420094541 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Нет в наличии.
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