Описание: Despite the large U.S. investment in health science, and the vast and growing body of peer-reviewed research findings it has produced, a compelling body of evidence suggests that research too often has been slow, inefficient, and fallen short of desired impacts on health. A key question is how research might be changed to be more innovative, less wasteful, and more responsive to unmet health needs. One emerging response within clinical and translational science is to advance an approach that attempts to close the gap between research scientists and key stakeholders; the individuals and groups responsible for or affected by health-related decisions. Broadly engaged team science promises to support this aim by transforming the gold standard, multi-disciplinary team science, to include key stakeholders in activities across the research spectrum. These new roles and responsibilities range from generating research questions to implementing research projects, to aiding in the translation of discoveries from the laboratory to the community. A transition to broadly engaged team science reflects the idea that inclusivity and a diversity of perspectives are necessary to achieving progress in addressing complex health issues while representing a new benchmark for ethical research practice. This is one of the first collections of papers describing how clinical and translational science researchers are defining and implementing new research practices, and the successes and challenges involved. This book represents a first and critical step towards organizing knowledge of broadly engaged team science and advancing the development of evidence-based practices. Written in an accessible style, this book is intended to highlight the breadth of broadly engaged team science within one community, motivate researchers and stakeholders to build inclusive teams, bring rigor to often informal stakeholder engagement research practices and encourage people to think more broadly about the development of scientific knowledge. It includes examples of multi-disciplinary, broadly engaged team science projects, the perspectives of academic leaders about the changes needed to encourage scientists to conduct broadly engaged team science, and a resource directory.
Автор: Mittal Sandeep Название: Targeting the Broadly Pathogenic Kynurenine Pathway ISBN: 3319363212 ISBN-13(EAN): 9783319363219 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Tryptophan metabolism via kynurenine pathway plays a critical role in both health and a variety of human diseases. This book highlights the known associations between kynurenine pathway and various disease states, as well as examines the current status of drug development and clinical trials of compounds known to alter tryptophan metabolism. The research plays a critical role in molecular targeted therapies directed at altering the kynurenine pathway of tryptophan metabolism. The initial and rate-limiting step of tryptophan metabolism is mediated by one of two enzymes, tryptophan-2,3-dioxygenase (TDO; predominantly in the liver, but also in the brain) and indoleamine-2,3-dioxygenase (IDO; in a host of tissues in response to immune activation). Targeting the enzymes IDO and TDO, as well as other downstream effectors would therefore be likely to generate novel treatment options that would be helpful in a wide variety of clinical settings. This book provides a unique bridge between basic mechanistic understanding of the role of the kynurenine pathway with translational applications and clinical relevance. It will explore the indications that tryptophan metabolism is a potential biomarker of disease activity, can contribute to local and possibly systemic immune suppression in cancer, and is an attractive target for which a variety of inhibitors are readily available.
Автор: Broad, Rosemary, Название: Demystifying modern slavery / ISBN: 0367149303 ISBN-13(EAN): 9780367149307 Издательство: Taylor&Francis Рейтинг: Цена: 22176.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Who are the perpetrators of modern slavery? Why do they exploit others and what might be done to stop that exploitation? Reporting on the first primary study of modern slavery offenders, the book depicts the findings of in-depth interviews with people accused of, and convicted for, committing modern slavery offences
Автор: Broad Garrett M. Название: More Than Just Food: Food Justice and Community Change ISBN: 0520287452 ISBN-13(EAN): 9780520287457 Издательство: Wiley Рейтинг: Цена: 3960.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Explores the possibilities and limitations of the community-based approach, offering a networked examination of the food justice movement in the age of the non-profit industrial complex.
Автор: Broad Garrett M. Название: More Than Just Food: Food Justice and Community Change ISBN: 0520287444 ISBN-13(EAN): 9780520287440 Издательство: Wiley Рейтинг: Цена: 12672.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Focusing on the work of several food justice groups - including Community Services Unlimited, a South Los Angeles organization founded as the nonprofit arm of the Southern California Black Panther Party - this title explores the possibilities and limitations of the community-based approach, and more.
Автор: A. Broadbent Название: Philosophy of Epidemiology ISBN: 1349346853 ISBN-13(EAN): 9781349346851 Издательство: Springer Рейтинг: Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Epidemiology is one of the fastest growing and increasingly important sciences. This thorough analysis lays out the conceptual foundations of epidemiology, identifying traps and setting out the benefits of properly understanding this fascinating and important discipline, as well as providing the means to do so.
Описание: This thesis presents an experimental study of quantum memory based on cold atomic ensembles and discusses photonic entanglement. It mainly focuses on experimental research on storing orbital angular momentum, and introduces readers to methods for storing a single photon carried by an image or an entanglement of spatial modes. The thesis also discusses the storage of photonic entanglement using the Raman scheme as a step toward implementing high-bandwidth quantum memory. The storage of photonic entanglement is central to achieving long-distance quantum communication based on quantum repeaters and scalable linear optical quantum computation. Addressing this key issue, the findings presented in the thesis are very promising with regard to future high-speed and high-capacity quantum communications.
Автор: Ferenc Toth Название: Cost-Benefit Analyses of Climate Change ISBN: 3034898312 ISBN-13(EAN): 9783034898317 Издательство: Springer Рейтинг: Цена: 10258.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The Potsdam Institute for Climate Impact Research (PIK) was founded in 1992 as a "Blue List" research institute, with the Federal Ministry for Education, Science, Research and Technology and the Ministry for Science, Research and Culture of the federal state of Brandenburg each provid- ing half ofthe funding.
Описание: This book offers a new concept of inclusion of the marginalised in India - the Broad-basing Process. It examines how marginalised groups can enter the social, political and economic mainstream and derive the same advantages as the groups already part of it.
Автор: Nadkarni, M. V. Название: Socio-Economic Change and the Broad-Basing Process in India ISBN: 0367727609 ISBN-13(EAN): 9780367727604 Издательство: Taylor&Francis Рейтинг: Цена: 6889.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Jitsuzumi Toshiya, Mitomo Hitoshi Название: Policies and Challenges of the Broadband Ecosystem in Japan ISBN: 9811680035 ISBN-13(EAN): 9789811680038 Издательство: Springer Рейтинг: Цена: 19514.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Foreword.- Introduction.- Chapter 1. Development of Infrastructure Sharing in the Mobile Market.- Chapter 2. Regulating Online Platforms.- Chapter 3. Interdependency on the Data Platform and its Effect on the Diffusion of Autonomous Driving.- Chapter 4. Video/Visual Content Industry in Japan.- Chapter 5. 5G trends and its use cases.- Chapter 6. Measures to develop AI human resources in Japan- Society 5.0 and investment in the next generation.- Chapter 7. New competition in regulated service markets after smartphone diffusion: Regulations on ride-hailing services in Japan.- Chapter 8. The preference of payment of game players in the cross-platform era: Based on the results of a survey of smartphone users in Japan, the U.K. and China.- Chapter 9. Acceptability of the "Right to be Forgotten" in Japan.- Chapter 10. The economic value of personal information: analysis of information leakage incidents.
Автор: Bernd Holznagel; Arnold Picot; Sebastian Deckers; Название: Strategies for Rural Broadband ISBN: 3834924199 ISBN-13(EAN): 9783834924193 Издательство: Springer Рейтинг: Цена: 10976.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Preface The importance of broadband Internet is a topic that is receiving much attention. The availability of broadband in rural areas has been low; the overcoming of this gap - tween population-sparse and population-dense areas has been a key issue on the - formation society agenda. Decision-makers - at municipal and national levels - are facing increasing pressure to overcome these discrepancies. This book seeks to provide insights for immediate action on two levels. Firstly, the management perspective addresses the economic relevance of broadband and feasible business models. The second part of the book takes a legal perspective, providing - nicipal decision-makers with guidelines for the swift implementation and the legal f- sibility of rural broadband rollout solutions. This dual approach combines the legal perspective with the field of business administration as well as economic restrictions with the field of law. Interdisciplinarity is crucial within this context. Allowances must be made for the form and format of both parts of the book. The authors have chosen to retain the legal and economic specifics in order to ensure usability in both areas. This book predominantly addresses people working with business models, broadband - searchers as well as decision-makers and politicians evaluating the legal feasibility of broadband rollout projects at a municipal level. Therefore, the first part of the book focuses on the economical feasibility of rural broadband rollout strategies - including an international comparative analysis - as well as the sustainability of broadband technologies.
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