This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Peter Atkins, Loretta Jones Название: Chemical Principles: The Quest for Insight ISBN: 1319154190 ISBN-13(EAN): 9781319154196 Издательство: Macmillan Learning Рейтинг: Цена: 14452.00 р. Наличие на складе: Нет в наличии.
Описание: Written for calculus-inclusive general chemistry courses, Chemical Principles helps students develop chemical insight by showing the connections between fundamental chemical ideas and their applications.
Автор: John Kuriyan, Carl-Ivar Branden and Michael Levitt Название: The Molecules of Life Physical and Chemical Principles ISBN: 0815341881 ISBN-13(EAN): 9780815341888 Издательство: Wiley Рейтинг: Цена: 8395.00 р. Наличие на складе: Поставка под заказ.
Описание: Understanding the physical properties that make life possible.
Описание: This book is intended for advanced undergraduate and graduate students. The first four chapters are devoted to the introduction of the finite element concept. The focus of the book then covers two essential areas - heat transfer and fluid mechanics: topics with different finite element formulations.
Автор: Dmitri Bessarabov, Haijiang Wang, Hui Li, Nana Zha Название: PEM Electrolysis for Hydrogen Production: Principles and Applications ISBN: 1138775495 ISBN-13(EAN): 9781138775497 Издательство: Taylor&Francis Рейтинг: Цена: 14851.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
An ever-increasing dependence on green energy has brought on a renewed interest in polymer electrolyte membrane (PEM) electrolysis as a viable solution for hydrogen production. While alkaline water electrolyzers have been used in the production of hydrogen for many years, there are certain advantages associated with PEM electrolysis and its relevance to renewable energy sources. PEM Electrolysis for Hydrogen Production: Principles and Applications discusses the advantages of PEM electrolyzers over alkaline electrolyzers, presents the recent advances of hydrogen PEM fuel cells accelerating the large-scale commercialization of PEM electrolysis, and considers the challenges that must be addressed before PEM electrolysis can become a commercially feasible option.
Written by international scientists in PEM electrolysis and fuel cell research areas, this book addresses the demand for energy storage technologies that store intermittent renewable energy and offers the most complete and up-to-date information on PEM electrolysis technology and research.
The authors:
Cover the fundamental applications of PEM electrolysis
Review the state-of-the-art technologies and challenges related to each of the components of the PEM electrolysis
Address failure analysis and review available failure diagnostic tools
Provide future direction for researchers and technology developers
PEM Electrolysis for Hydrogen Production: Principles and Applications provides a fundamental understanding of the requirements and functionalities of certain components and attributes of the PEM electrolysis technology that are common for both PEM fuel cells' and electrolyzers' hydrogen applications for energy storage. Beneficial to students and professionals, the text serves as a handbook for identifying PEM electrolysis failure modes and diagnosing electrolyzer performance to improve efficiency and durability.
Описание: Different numerical and analytical methods have been employed to find the solution of governing equations for nanofluid flow and heat transfer.Applications of Nanofluid Transportation and Heat Transfer Simulation provides emerging research exploring the theoretical and practical aspects and applications of heat and nanofluid transfer. With practical examples and proposed methodology, it features coverage on a broad range of topics such as nanoparticles, electric fields, and hydrothermal behavior, making it an ideal reference source for engineers, researchers, graduate students, professionals, and academics.
Описание: This book presents a new computational methodology called Computational Mass Transfer (CMT). It details a rigorous model for the simulation of concentration, temperature and velocity distributions in chemical and related processes.
Описание: Principles of Heat and Mass Transfer is the gold standard of heat transfer pedagogy for more than 30 years, with a commitment to continuous improvement by the authors. Using a rigorous and systematic problem-solving methodology pioneered by this text, it is abundantly filled with examples and problems that reveal the richness and beauty of the discipline. This edition maintains its foundation in the four central learning objectives for students and also makes heat and mass transfer more approachable with an additional emphasis on the fundamental concepts, as well as highlighting the relevance of those ideas with exciting applications to the most critical issues of today and the coming decades: energy and the environment. An updated version of Interactive Heat Transfer (IHT) software makes it even easier to efficiently and accurately solve problems.
Автор: Forsberg, Charles H. Название: Heat Transfer Principles And Applications ISBN: 0128022965 ISBN-13(EAN): 9780128022962 Издательство: Elsevier Science Рейтинг: Цена: 15831.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Heat Transfer Principles and Applications is a welcome change from more encyclopedic volumes exploring heat transfer. This shorter text fully explains the fundamentals of heat transfer, including heat conduction, convection, radiation and heat exchangers. The fundamentals are then applied to a variety of engineering examples, including topics of special and current interest like solar collectors, cooling of electronic equipment, and energy conservation in buildings. The text covers both analytical and numerical solutions to heat transfer problems and makes considerable use of Excel and MATLAB(R) in the solutions. Each chapter has several example problems and a large, but not overwhelming, number of end-of-chapter problems.
Автор: Frenier, Wayne W., Название: Chemical and mechanical methods for pipeline integrity / ISBN: 1613994966 ISBN-13(EAN): 9781613994962 Издательство: Society of Petroleum Engineers Цена: 31350.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Providing a comprehensive overview of the science and technology behind maintaining pipelines, Chemical and Mechanical Methods of Pipeline Integrity was written for oil and gas professionals responsible for ensuring consistent product delivery. Wayne Frenier details in this new book a variety of pipeline environments and then explores the challenges that require chemical or mechanical intervention. Internal corrosion and the corrosion mechanisms that affect pipeline and facility operations are included in the discussion along with a short introduction to Integrity Management processes. With a strong focus on the connections between the production of hydrocarbons, production facilities, and the pipelines that take the products to the refineries, Chemical and Mechanical Methods of Pipeline Integrity was written for a general technical audience with a basic understanding of chemistry.
Автор: Ashok D. Belegundu, Tirupathi R. Chandrupatla Название: Optimization Concepts and Applications in Engineering ISBN: 1108424880 ISBN-13(EAN): 9781108424882 Издательство: Cambridge Academ Рейтинг: Цена: 16474.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A revised and expanded third edition, this book integrates theory, modeling, the development of numerical methods, and problem solving to apply optimization to real-world problems. This book is ideal for advanced undergraduate, graduate and applied mathematics courses as well as practicing engineers.
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