Описание: This book reviews the latest developments in the design, synthesis, and molecular mechanism of action of Histone Deacetylase (HDAC) inhibitors in the context of potential cancer therapy.
Автор: Lisa B. English Название: Combinatorial Library ISBN: 1489938990 ISBN-13(EAN): 9781489938992 Издательство: Springer Рейтинг: Цена: 15957.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent advances in com- natorial library synthesis, purification, and analysis techniques are not only increasing the numbers of compounds that can be tested against each specific genomic target, but are also speeding and improving the overall processes of lead discovery and optimization.
Автор: Shmuel Cabilly Название: Combinatorial Peptide Library Protocols ISBN: 1617370223 ISBN-13(EAN): 9781617370229 Издательство: Springer Рейтинг: Цена: 17684.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: While working with these libraries, we noticed the interesting fact that when combinatorial libraries of oligopeptides were allowed to interact with different selector proteins, only the actual binding sites of these proteins showed binding properties, whereas the rest of the p- tein surface seemed "inert.
Автор: W.H. Moos; M.R. Pavia; B.K. Kay; Andrew D. Ellingt Название: Annual Reports in Combinatorial Chemistry and Molecular Diversity ISBN: 9401707383 ISBN-13(EAN): 9789401707381 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs.
Описание: This book reviews the latest developments in the design, synthesis, and molecular mechanism of action of Histone Deacetylase (HDAC) inhibitors in the context of potential cancer therapy.
Автор: Christopher Schirwitz Название: Purification of Peptides in High-Complexity Arrays ISBN: 3319008064 ISBN-13(EAN): 9783319008066 Издательство: Springer Рейтинг: Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book outlines an improvement of the quality of in situ synthesized high-complexity peptide micro arrays. It details the development of a new method allowing for fast one-step purification of entire arrays without loss of resolution or spatial information.
Автор: Michael A. R. Meier; Dean C. Webster Название: Polymer Libraries ISBN: 3642263410 ISBN-13(EAN): 9783642263415 Издательство: Springer Рейтинг: Цена: 38908.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: However, the tuning of polymer composition and structure as well as polymer formulations to optimize the ?nal performance properties can be challenging, - pecially since in many cases several interacting variables need to be optimized simultaneously.
Автор: Brunschweiger Название: DNA-Encoded Libraries ISBN: 3031186281 ISBN-13(EAN): 9783031186288 Издательство: Springer Рейтинг: Цена: 36589.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book deals with the recent advances in DNA-Encoded Library (DEL) technology that has emerged as an alternative to high throughput screening (HTS) over the last decade and has been heralded as a "disruptive" technology for drug discovery. The book aims to provide a comprehensive overview of all of the major components of the DEL process from conception to bench execution and clinical investigations. The contributions from experts in the field combine different perspectives from academia and industry. The book will be of interest to researchers in the drug discovery field as well as to graduate students and scholars who are interested in this rapidly improving technology.
Автор: Titlebaum, Mike (Ithaca College, USA) Название: Chiral Ligands ISBN: 0367428482 ISBN-13(EAN): 9780367428488 Издательство: Taylor&Francis Рейтинг: Цена: 29093.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Many new drugs on the market are chiral compounds, that is, they can exist in two non-superimposable mirror-image forms. Asymmetric catalysis encompasses a large variety of processes for obtaining such compounds.
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