Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
Автор: Cheng Zhen Название: Fluorescent Imaging in Medicinal Chemistry ISBN: 3030467066 ISBN-13(EAN): 9783030467067 Издательство: Springer Рейтинг: Цена: 46347.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews the most recent developments of fluorescent imaging techniques for medicinal chemistry research and biomedical applications, including cell imaging, in vitro diagnosis and in vivo imaging. Fluorescent imaging techniques play an important role in basic research, drug discovery and clinical translation.
Автор: Sabnis Название: Handbook of Fluorescent Dyes and Probes ISBN: 1118028694 ISBN-13(EAN): 9781118028698 Издательство: Wiley Рейтинг: Цена: 23118.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A COMPLETE, UP-TO-DATE RESOURCE OF INFORMATION ON MORE THAN 150 FLUORESCENT DYES AND PROBES Handbook of Fluorescent Dyes and Probes is the most comprehensive volume available on the subject, covering all the available dyes and probes known to date in the literature for uses in various fields. Top dye expert Dr.
Автор: Xu Jiarui, Chi Zhenguo, Schneider Hans-Jorg Название: Mechanochromic Fluorescent Materials: Phenomena, Materials and Applications ISBN: 1849738211 ISBN-13(EAN): 9781849738217 Издательство: Royal Society of Chemistry Рейтинг: Цена: 24552.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction to the concept of mechanofluorochromism and the variety of applications of this group of materials.
Автор: Kaur Название: Fluorescent Tools for Imaging Oxidative Stress in Biology ISBN: 3319734040 ISBN-13(EAN): 9783319734040 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction.- Flavin based redox probes.- FRET based ratiometric redox probes.- Mitochondrially-targeted ratiometric redox probes.- Nicotinamide based ratiometric probes.- In cellulo studies.- Ex vivo studies.- Non-mammalian systems.- Conclusions.- Experimental Methods.
Автор: Robert Hoffman Название: In Vivo Cellular Imaging Using Fluorescent Proteins ISBN: 1493961497 ISBN-13(EAN): 9781493961498 Издательство: Springer Рейтинг: Цена: 14635.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This Methods in Molecular Biology (TM) book ranges from the employment of the chick CAM model using fluorescent proteins and other fluorescent probes to intravital fluorescent imaging, 3-dimensional imaging and making new far-red and infrared fluorescent proteins.
Автор: Amandeep Kaur Название: Fluorescent Tools for Imaging Oxidative Stress in Biology ISBN: 3030103714 ISBN-13(EAN): 9783030103712 Издательство: Springer Рейтинг: Цена: 17074.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This thesis advances the long-standing challenge of measuring oxidative stress and deciphering its underlying mechanisms, and also outlines the advantages and limitations of existing design strategies. It presents a range of approaches for the chemical synthesis of fluorescent probes that detect reversible changes in cellular oxidative stress. The ability to visualise cellular processes in real-time is crucial to understanding disease development and streamline treatment, and this can be achieved using fluorescent tools that can sense reversible disturbances in cellular environments during pathogenesis. The perturbations in cellular redox state are of particular current interest in medical research, since oxidative stress is implicated in the pathogenesis of a number of diseases.The book investigates different strategies used to achieve ratiometric fluorescence output of the reversible redox probes, which nullify concentration effects associated with intensity-based probes. It also describes suitable approaches to target these probes to specific cellular organelles, thereby enabling medical researchers to visualise sub-cellular oxidative stress levels, and addressing the typically poor uptake of chemical tools into biological studies. In total it reports on four new probes that are now being used by over twenty research groups around the globe, and two of which have been commercialised. The final chapters of this thesis demonstrate successful applications of the sensors in a variety of biological systems ranging from prokaryotes to mammalian cells and whole organisms. The results described clearly indicate the immense value of collaborative, cross-disciplinary research.
Автор: Wu Fu-Gen Название: Fluorescent Materials for Cell Imaging ISBN: 9811550611 ISBN-13(EAN): 9789811550614 Издательство: Springer Цена: 21953.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents recently developed fluorescent materials, including semiconductor quantum dots, carbon dots, silicon nanoparticles, metal nanoclusters, upconversion nanoparticles, conjugated polymers/polymer dots, aggregation-induced emission (AIE) probes, and coordination compounds, used for various cellular imaging purposes.
Автор: Hicks Название: Green Fluorescent Proteins + CD ISBN: 0896039056 ISBN-13(EAN): 9780896039056 Издательство: Springer Рейтинг: Цена: 17684.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Barry W. Hicks and a team of well-practiced experimentalists demonstrate the power and the versatility of the green fluorescent protein (GFP) marker with a cutting-edge collection of readily reproducible GFP techniques. These include methods for detecting and imaging GFP (FRET, BRET, and whole-body imaging); for using GFP to create and select for transgenic organisms, for its use as a biosensor; and for studying viruses. A valuable companion CD-ROM displays many color figures and videos from over half the chapters.
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