The Biology of Senescence, Bernard Swynghedauw

Автор: Peter D. Adams; John M. Sedivy
Название: Cellular Senescence and Tumor Suppression
ISBN: 1441910743 ISBN-13(EAN): 9781441910745
Издательство: Springer
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Цена: 23173.00 р.
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Описание: This book covers the latest findings in the link between cellular senescence and cancer including telemores and senescence signals, the senescent phenotype, and the physiological effects of senescence, including therapeutic applications.

Автор: Peter D. Adams; John M. Sedivy
Название: Cellular Senescence and Tumor Suppression
ISBN: 1489983562 ISBN-13(EAN): 9781489983565
Издательство: Springer
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Цена: 20733.00 р.
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Описание: As cells mature they naturally stop dividing and enter a period called senescence. But cellular senescence can also be induced prematurely by certain oncogenes involved in cancer development. Cellular senescence, a growth-arrest program that limits the lifespan of mammalian cells and prevents unlimited cell proliferation, is attracting considerable interest because of its links to tumor suppression.

Автор: Suresh I.S. Rattan; Leonard Hayflick
Название: Cellular Ageing and Replicative Senescence
ISBN: 3319262378 ISBN-13(EAN): 9783319262376
Издательство: Springer
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Цена: 19377.00 р.
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Описание: This book covers the origins and subsequent history of research results in which attempts have been made to clarify issues related to cellular ageing, senescence, and age-related pathologies including cancer.

Автор: Rattan Suresh I. S., Hayflick Leonard
Название: Cellular Ageing and Replicative Senescence
ISBN: 3319799126 ISBN-13(EAN): 9783319799124
Издательство: Springer
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Цена: 12196.00 р.
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Описание: This book covers the origins and subsequent history of research results in which attempts have been made to clarify issues related to cellular ageing, senescence, and age-related pathologies including cancer. Cellular Ageing and Replicative Senescence revisits more than fifty-five years of research based on the discovery that cultured normal cells are mortal and the interpretation that this phenomenon is associated with the origins of ageing. The mortality of normal cells and the immortality of cancer cells were also reported to have in vivo counterparts. Thus began the field of cytogerontology. Cellular Ageing and Replicative Senescence is organized into five sections: history and origins; serial passaging and progressive ageing; cell cycle arrest and senescence; system modulation; and recapitulation and future expectations. These issues are discussed by leading thinkers and researchers in biogerontology and cytogerontology. This collection of articles provides state-of-the-art information, and will encourage students, teachers, health care professionals and others interested in the biology of ageing to explore the fascinating and challenging question of why and how our cells age, and what can and cannot be done about it.