Ulla G. Knaus; Thomas L. Leto NADPH Oxidases 9781493994267

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Автор: Ulla G. Knaus; Thomas L. Leto
Название: NADPH Oxidases
ISBN: 9781493994267
Издательство: Springer
Классификация:

Физиология

Медицинская генетика

Энзимология

ISBN-10: 1493994263
Обложка/Формат: Soft cover
Страницы: 718
Вес: 1.38 кг.
Дата издания: 2019
Серия: Methods in Molecular Biology
Язык: English
Иллюстрации: XV, 718 p. 155 illus., 111 illus. in color.
Читательская аудитория: Professionals
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This detailed volume explores the NADPH oxidase family of enzymes in human physiology and genetic disease, in which early discoveries represent prime examples of the finest translational “from bed to bench and back” studies. Methods are included for testing assembly and function of multicomponent oxidase complexes and for analyzing reactive oxygen species (ROS) generation in different systems by various means, while addressing pitfalls of ROS probes currently being used, as well as protocols on NADPH oxidase regulation and their function in cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, NADPH Oxidases: Methods and Protocols will aid researchers working with the NOX/DUOX family in continuing and expanding upon their vital research.
Дополнительное описание: Intersecting Stories of the Phagocyte NADPH Oxidase and Chronic Granulomatous Disease.- Mammalian NADPH Oxidases.- Enhanced Immunoaffinity Purification of Human Neutrophil Flavocytochrome B for Structure Determination by Electron Microscopy.- Purification

NADPH Oxidases, Ulla G. Knaus; Thomas L. Leto