Long Non-Coding Rnas in Human Disease, Morris Kevin V.

Название: Long non-coding rnas in human disease
ISBN: 3319239066 ISBN-13(EAN): 9783319239064
Издательство: Springer
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Цена: 17097.00 р.
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Описание: The role oflncRNAs in X-inactivation and those lncRNAs derived from pseudogenes, pastretroelements integrated within the human genome, as well as the role thesepseudogene-derived lncRNAs play in cancer development are discussed in detail.

Автор: Song Erwei
Название: The Long and Short Non-Coding Rnas in Cancer Biology
ISBN: 9811093679 ISBN-13(EAN): 9789811093678
Издательство: Springer
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Цена: 18294.00 р.
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Описание: Non-coding RNAs: New Players in Cancers.- The Working Modules of Long Non-coding RNAs in Cancer Cells.- Methods to Study Long Non-coding RNA Biology in Cancer.- Relationship between Non-coding RNA Dysregulation and Epigenetic Mechanisms in Cancer.- Non-coding RNAs in Growth and Death of Cancer Cells.- Non-coding RNAs in Cancer Cell Plasticity.- Non-coding RNAs in Regulation of Cancer Metabolic Reprogramming.- Non-coding RNAs in Tumor Angiogenesis.- Non-coding RNAs in Cancer Immunity.- Non-coding RNAs in Therapeutic Resistance of Cancer.- Non-coding RNAs Regulating Cancer Signaling Network.- Non-coding RNAs Regulating NFkB Signaling.- Non-coding RNAs Regulating p53 and c-Myc Signaling.- Viral Non-coding RNAs in Cancer Biology.- Non-coding RNAs in Cancer Diagnosis.- Therapeutic Potentials of Non-coding RNAs: Targeted Delivery of NcRNAs in Cancer Cells.

Автор: Yi Feng; Lin Zhang
Название: Long Non-Coding RNAs
ISBN: 1493933760 ISBN-13(EAN): 9781493933761
Издательство: Springer
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Цена: 17074.00 р.
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Описание: This volume assembles a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA.

Автор: Yi Feng; Lin Zhang
Название: Long Non-Coding RNAs
ISBN: 1493980351 ISBN-13(EAN): 9781493980352
Издательство: Springer
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Цена: 13415.00 р.
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Описание: This volume assembles a broad spectrum of methods used in long non-coding RNAs (lncRNA) research, ranging from computational annotation of lncRNA genes to molecular and cellular analyses of the function of individual lncRNA.

Автор: Ahmad M. Khalil
Название: Molecular Biology of Long Non-coding RNAs
ISBN: 3030170853 ISBN-13(EAN): 9783030170851
Издательство: Springer
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Цена: 13415.00 р.
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Описание: This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them.

Автор: Khalil Ahmad M.
Название: Molecular Biology of Long Non-Coding Rnas
ISBN: 3030170888 ISBN-13(EAN): 9783030170882
Издательство: Springer
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Цена: 13415.00 р.
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Описание: This second edition shows how long non-coding RNAs (lnc)RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Advances in the field also include better characterization of human long non-coding RNAs, novel insights into their roles in human development and disease, their diverse mechanisms of action and novel technologies to study them.

Автор: Ahmad M. Khalil; Jeff Coller
Название: Molecular Biology of Long Non-coding RNAs
ISBN: 1493945289 ISBN-13(EAN): 9781493945283
Издательство: Springer
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Цена: 17096.00 р.
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Описание: This book examines key issues in lncRNA biology, including critical studies that have led to the discovery and annotation of lncRNAs in numerous species and the molecular mechanisms for a few lncRNA that have begun to emerge.

Автор: Song
Название: The Long and Short Non-coding RNAs in Cancer Biology
ISBN: 9811014965 ISBN-13(EAN): 9789811014963
Издательство: Springer
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Цена: 20516.00 р.
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Описание: The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.

Автор: ?ur?ica Ugarkovi?
Название: Long Non-Coding RNAs
ISBN: 364226655X ISBN-13(EAN): 9783642266553
Издательство: Springer
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Цена: 20516.00 р.
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Описание: Long Non-Coding RNAs provides an overview of the rapidly advancing field, and describes the epigenetic and non-epigenetic mechanisms by which they regulate various biological functions in model systems. Readers will find a discussion of the role of ncRNAs in sex chromosome dosage compensation, and more.

Автор: Slaby
Название: Non-coding RNAs in Colorectal Cancer
ISBN: 3319420577 ISBN-13(EAN): 9783319420578
Издательство: Springer
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Цена: 19514.00 р.
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Описание: This is the first book to provide a broad framework for obtaining an in depth understanding of the state-of-the-art knowledge on abnormalities of non-coding RNAs found to be associated with colorectal cancer pathogenesis. Readers will discover possible mechanisms underlying the substantial roles played by non-coding RNAs in molecular hallmarks of colorectal cancer. This work further provides the comprehensive overview and novel insights into using of non-coding RNAs as colorectal cancer biomarkers enabling early detection of the disease, prognostic stratification of the patients and prediction of therapeutic response. The reader is introduced to the overview of modern non-coding RNAs-based therapeutic strategies, and summary of their preclinical testing performed in colorectal cancer. The work is written for researchers who want to explore current state of the knowledge in this interesting field of molecular oncology.

Автор: Gordon G. Carmichael
Название: Regulatory Non-Coding RNAs
ISBN: 1493913689 ISBN-13(EAN): 9781493913688
Издательство: Springer
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Цена: 17074.00 р.
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Описание: Regulatory Non-Coding RNAs: Methods and Protocols offers a collection of methods for those interested in the discovery, localization, and functional analysis of these non-coding transcripts that have the potential and ability to orchestrate and control gene expression.

Автор: Volker A. Erdmann; Jan Barciszewski
Название: Non Coding RNAs in Plants
ISBN: 3642269990 ISBN-13(EAN): 9783642269998
Издательство: Springer
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Цена: 22796.00 р.
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Описание: Discovered just 20 years ago, ncRNAs have been dubbed the `secret regulators` of cells. Only recently has their function in plants been investigated. In this book leading researchers relate recent discoveries about the role played by small ncRNA in plants.