Описание: This volume will describe recent progress and future directions in radiation oncology and biology research, focusing on strategies designed to improve disease control and reduce the risk of long-term adverse effects on patients. As more and more patients are becoming long-term survivors, this strategy will become increasingly important--in radiation oncology and throughout the field of oncology.
Автор: Philip J. Tofilon; Kevin Camphausen Название: Increasing the Therapeutic Ratio of Radiotherapy ISBN: 3319408526 ISBN-13(EAN): 9783319408521 Издательство: Springer Рейтинг: Цена: 20733.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal tissues. The goal of this volume is to describe a number of promising approaches corresponding to each strategy.
In general, research in radiation oncology tends to be siloed into fundamental biology, physics or treatment delivery. The strategies for improving therapeutic ratio encompassed in this book will involve each of these components of radiation oncology. Thus, they will illustrate the variety of disparate approaches available for potentially improving the efficacy of radiotherapy, which may then stimulate discussion across disciplines and foster further translational investigations.
Although a goal of each chapter will be to highlight advances within an approach, of equal importance will be the delineation of barriers to successful clinical application and how to overcome or minimize such impediments. Along these lines, because therapeutic ratio incorporates both tumor and normal tissue radio response, a point of emphasis will be the mechanistic rationale for selectively modifying tumor (sensitization) or normal cells (protection).
Finally, whereas the literature is replete with studies describing potential targets/strategies for increasing the therapeutic ratio for radiotherapy, this book will focus on those supported by in vivo data consistent with impending translational application along with those that are already being evaluated in the clinic.
Автор: Tofilon Philip J., Camphausen Kevin Название: Increasing the Therapeutic Ratio of Radiotherapy ISBN: 3319822012 ISBN-13(EAN): 9783319822013 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal tissues.
Автор: Xia, Ping Godley, Andrew Shah, Chirag Suh, John Название: Strategies for radiation therapy treatment planning ISBN: 0826122442 ISBN-13(EAN): 9780826122445 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 10032.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides a step-by-step guide to implementing external beam treatment plans that meet clinical requirements for each major disease site. The book focuses on the technical aspects of treatment planning and the major challenges in creating highly conformal dose distributions, referenced to as treatment plans, for external beam radiotherapy.
Автор: Christian Herfarth; Peter Schlag; Peter Hohenberge Название: Therapeutic Strategies in Primary and Metastatic Liver Cancer ISBN: 3642826377 ISBN-13(EAN): 9783642826375 Издательство: Springer Рейтинг: Цена: 15855.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Therapeutic concepts comprise sys- temic therapy and organ-related therapeutic methods, in- cluding surgical resection, changes in the blood supply, re- gional selective chemotherapy, and other localized or regional, highly specialized forms of therapy.
Автор: Stark Malcolm Название: Pancreatic Cancer: Evaluation and Therapeutic Strategies ISBN: 1632427397 ISBN-13(EAN): 9781632427397 Издательство: Неизвестно Рейтинг: Цена: 23335.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
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