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Progranulin and Central Nervous System Disorders, Hara Hideaki, Hosokawa Masato, Nakamura Shinsuke


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Автор: Hara Hideaki, Hosokawa Masato, Nakamura Shinsuke
Название:  Progranulin and Central Nervous System Disorders
ISBN: 9789811361883
Издательство: Springer
Классификация:



ISBN-10: 9811361886
Обложка/Формат: Paperback
Страницы: 183
Вес: 0.28 кг.
Дата издания: 14.08.2020
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 50 tables, color; 13 illustrations, color; 24 illustrations, black and white; vii, 183 p. 37 illus., 13 illus. in color.
Размер: 23.39 x 15.60 x 1.04 cm
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This book presents the latest knowledge on the roles of progranulin (PGRN) in normal physiology and pathology and explores the emerging significance of PGRN as a therapeutic target and biomarker in various CNS disorders, including frontotemporal lobe degeneration and other neurodegenerative diseases.


Iron in Central Nervous System Disorders

Автор: Peter Riederer; M.B.H. Youdim
Название: Iron in Central Nervous System Disorders
ISBN: 3211825207 ISBN-13(EAN): 9783211825204
Издательство: Springer
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Цена: 10610.00 р.
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Описание: Thus nutritional iron defi- ciency and iron overload afflict some 500-600 million people. It is also well recognized that too little or too much iron can produce profound effects on the metabolic state of the cell, and therefore the regulation of iron uptake and disposition is tightly relegated by the cell.

Injury Models of the Central Nervous System

Автор: Firas H. Kobeissy et al
Название: Injury Models of the Central Nervous System
ISBN: 1493938142 ISBN-13(EAN): 9781493938148
Издательство: Springer
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Цена: 21953.00 р.
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Описание: This volume discusses experimental brain injury models thatcontain valuable information carefully chosen to widen the researchers’ horizonabout neurotrauma. Injury Models of Central Nervous System: Methods and Protocols contains relevant experimental design approaches that have beenadapted and made ready for application in laboratory settings. For easiernavigation, the chapters are categorized into 6 parts: Introduction, GeneralConsideration in Using Animal Laboratory in CNS Injury Research, Classical TBIModels and Their Link with Pathophysiological Features of CBS Injury – Models,Special Topics in CNS Trauma: Comorbid Conditions in CNS Injury, OutcomeMeasures in Brain Injury Models, and Future Directions. Written in the highly successful Methods inMolecular Biology series format, chapters include introductions to theirrespective topics, lists of the necessary materials and reagents, step-by-step,readily reproducible laboratory protocols, and tips on troubleshooting andavoiding known pitfalls.Practical and thorough, Injury Models of Central Nervous Systems: Methods and Protocols, is a very useful reference towards theprogress of this discipline.

Central Nervous System Diseases

Автор: Dwaine F. Emerich; Reginald L. Dean III; Paul R. S
Название: Central Nervous System Diseases
ISBN: 089603724X ISBN-13(EAN): 9780896037243
Издательство: Springer
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Цена: 30370.00 р.
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Описание: A critical review of the animal models used in developing powerful new therapies for central nervous system diseases. Techniques that rely heavily on behavioural analyses, as well as models developed from infusions of neurotoxins and from advances in molecular biology, are thoroughly explicated.

Stem Cell Biology in Neoplasms of the Central Nervous System

Автор: Moneeb Ehtesham
Название: Stem Cell Biology in Neoplasms of the Central Nervous System
ISBN: 3319165364 ISBN-13(EAN): 9783319165363
Издательство: Springer
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Цена: 17074.00 р.
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Описание: This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used. The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.

Evaluation of Interstitial Nerve Cells in the Central Nervous System

Автор: G.D. Das; G.W. Kreutzberg
Название: Evaluation of Interstitial Nerve Cells in the Central Nervous System
ISBN: 3540040919 ISBN-13(EAN): 9783540040910
Издательство: Springer
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Цена: 15855.00 р.
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Описание: The presence of nerve cells in the white matter of the spinal cord and in the spinal and cranial nerves has attracted the attention of some researchers in the past.

Central Nervous System Pathology

Автор: G.N. Kryzhanovsky
Название: Central Nervous System Pathology
ISBN: 1468478729 ISBN-13(EAN): 9781468478723
Издательство: Springer
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Цена: 6097.00 р.
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Описание: One hardly always receives due credit for working out a general theory. Some of them are interested in analyzing the specifics of a phenomenon, while others try to find a general regularity in an individual fact and look for its confirmation in new material.

Axonal Regeneration in the Mammalian Central Nervous System

Автор: Dorothy E. Oorschot; David G. Jones
Название: Axonal Regeneration in the Mammalian Central Nervous System
ISBN: 354051757X ISBN-13(EAN): 9783540517573
Издательство: Springer
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5-HT2A Receptors in the Central Nervous System

Автор: Bruno P. Guiard; Giuseppe Di Giovanni
Название: 5-HT2A Receptors in the Central Nervous System
ISBN: 3319704729 ISBN-13(EAN): 9783319704722
Издательство: Springer
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Цена: 26832.00 р.
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Описание: 5-HT2A receptors are G-protein coupled receptors that are widely distributed throughout the brain, most notably on neuronal and glial cells. 5-HT2A receptors have been implicated in various central physiological functions including mood regulation, memory, sleep, nociception, eating, and reward behaviors, and they are also believed to control the cardiovascular system. This  book provides a comprehensive overview of these receptors including sections on their properties and distribution, approaches for their study, their role in a number of brain functions and diseases, and their role as therapeutic targets. ?

Plasticity of the Central Nervous System

Автор: Keiji Sano; Shozo Ishii
Название: Plasticity of the Central Nervous System
ISBN: 3709189470 ISBN-13(EAN): 9783709189474
Издательство: Springer
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Цена: 10610.00 р.
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Описание: Distinguished experts from the fields of neurosurgery, neurology, neurophysiology, anatomy, pathology, oncology, and pharmacology discussed the following topics: - Molecular and cellular basis of plasticity - Regeneration and growth in the CNS - Self-organization of neuronal network - Brain oedema - a reparatory process?

Isolated Central Nervous System Circuits

Автор: Klaus Ballanyi
Название: Isolated Central Nervous System Circuits
ISBN: 1493961837 ISBN-13(EAN): 9781493961832
Издательство: Springer
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Цена: 15855.00 р.
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Описание: This Neuromethods series volume offers protocols and examples for exciting results from the labs of renowned experts. Covers patch-clamp, multiphoton imaging, live fluorescent protein expression, immunohistochemistry techniques, `organotypic` slices and more.

Development of the Central Nervous System in Vertebrates

Автор: S.C. Sharma; A.M. Goffinet
Название: Development of the Central Nervous System in Vertebrates
ISBN: 1461363152 ISBN-13(EAN): 9781461363156
Издательство: Springer
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Цена: 6097.00 р.
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Описание: Proceedings of a NATO ASI held in Maratea, Italy, June 23-July 6, 1991.


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