Описание: Offers many antibiotics and antimicrobial compounds: in development, experimental, and in use. This title covers chemistry and synthesis, classification, structure-activity relationships, mechanisms of action and resistance, breakpoints, in vitro/in vivo activities, epidemiology, pharmacokinetics, metabolism, and adverse events.
Автор: J. F. Snell; J. W. Corcoran; K. L. Arora; F. E. Ha Название: Mechanism of Action of Antimicrobial and Antitumor Agents ISBN: 3642463061 ISBN-13(EAN): 9783642463068 Издательство: Springer Рейтинг: Цена: 6097.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume is the third in the series devoted to Antibiotics initiated by Springer Verlag in 1967.
Автор: Bueno Juan Название: Preclinical Evaluation of Antimicrobial Nanodrugs ISBN: 3030438546 ISBN-13(EAN): 9783030438548 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.
Автор: Djamel Drider; Sylvie Rebuffat Название: Prokaryotic Antimicrobial Peptides ISBN: 1489994777 ISBN-13(EAN): 9781489994776 Издательство: Springer Рейтинг: Цена: 22796.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book will provide an overview of the advancement of fundamental knowledge and applications of antimicrobial peptides in biomedical, agricultural, veterinary, food, and cosmetic products.
Автор: Chin-Yi Chen Название: Antimicrobial Resistance and Food Safety ISBN: 0128012145 ISBN-13(EAN): 9780128012147 Издательство: Elsevier Science Рейтинг: Цена: 15159.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Antimicrobial Resistance and Food Safety: Methods and Techniques introduces antimicrobial resistant food-borne pathogens, their surveillance and epidemiology, emerging resistance and resistant pathogens. This analysis is followed by a systematic presentation of currently applied methodology and technology, including advanced technologies for detection, intervention, and information technologies. This reference can be used as a practical guide for scientists, food engineers, and regulatory personnel as well as students in food safety, food microbiology, or food science.
Includes analysis of all major pathogens of concern
Provides many case studies and examples of fundamental research findings
Presents recent advances in methodologies and analytical software
Demonstrates risk assessment using information technologies in foodborne pathogens
Автор: Jeffrey K. Aronson Название: Meyler`s Side Effects of Antimicrobial Drugs, ISBN: 0444532722 ISBN-13(EAN): 9780444532725 Издательство: Elsevier Science Рейтинг: Цена: 8420.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Suitable for internal medicine physicians and general practitioners who prescribe antibiotic drugs, like penicillin and tetracycline that cure bacterial infections, and antiviral drugs used to treat patients with HIV and herpes viruses.
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