This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Patil Popat M Название: Discoveries In Pharmacological Sciences ISBN: 9814355070 ISBN-13(EAN): 9789814355070 Издательство: World Scientific Publishing Рейтинг: Цена: 27720.00 р. 39600.00-30% Наличие на складе: Есть (1 шт.) Описание: Throughout history, the perpetuation of species, the need for survival, and human curiosity, intelligence and skills provided the basis for the development of drug science. This title contains the history of herbal medicine as it emerged about 5,000 years ago.
Автор: Laurence Brunton, Bruce Chabner Название: Goodman And Gilman`s Pharmacological Basis Of Therapeutics 12 ed ISBN: 0071624422 ISBN-13(EAN): 9780071624428 Издательство: McGraw-Hill Рейтинг: Цена: 17503.00 р. 25004.00-30% Наличие на складе: Есть (1 шт.) Описание: A medical text that represents accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. It helps thousands of practitioners and students to an understanding of the drugs essential to preventing, diagnosing, and treating disease.
Автор: A. Claudio Cuello Название: Pharmacological Mechanisms in Alzheimer`s Therapeutics ISBN: 1441924469 ISBN-13(EAN): 9781441924469 Издательство: Springer Рейтинг: Цена: 23173.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The need for effective therapy to treat Alzheimer`s disease is greater than ever, but there is still no drug therapy that can stop or reverse the progression of the disease.
Название: Drugs, Ageing and Society ISBN: 1032687770 ISBN-13(EAN): 9781032687773 Издательство: Taylor&Francis Рейтинг: Цена: 15004.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: I.K. Morton; Judith M. Hall Название: Concise Dictionary of Pharmacological Agents ISBN: 0751404993 ISBN-13(EAN): 9780751404999 Издательство: Springer Рейтинг: Цена: 30370.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides a cross-indexed listing of pharmacologically active agents and their properties. This dictionary contains details of some 4000 individual chemical agents including medical drugs in use, experimental agents and toxins used as investigation tools. It includes an alphabetical glossary explaining the meaning of some 3000 biomedical terms.
Автор: Charles R. Schuster; Michael J. Kuhar Название: Pharmacological Aspects of Drug Dependence ISBN: 364264631X ISBN-13(EAN): 9783642646317 Издательство: Springer Рейтинг: Цена: 14818.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts
Автор: Gerard Emilien; Cecile Durlach; Ulla Lepola; Timot Название: Anxiety Disorders ISBN: 3034894600 ISBN-13(EAN): 9783034894609 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, the discussion of the normal and pathological aspects of anxiety is critically examined. Separate chapters dedicated to each particular type of anxiety such as generalized anxiety disorder, social phobia, posttraumatic stress disorder, panic and obsessive-compulive disorder are included.
Автор: Gnegy,Margaret E Название: Pharmacological Advances In Central Nervous System Stimulants,99 ISBN: 0443219338 ISBN-13(EAN): 9780443219337 Издательство: Elsevier Science Рейтинг: Цена: 29812.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: James E Barrett Название: Pharmacological Mechanisms and the Modulation of Pain,75 ISBN: 0128038837 ISBN-13(EAN): 9780128038833 Издательство: Elsevier Science Рейтинг: Цена: 29812.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
"Pharmacological Mechanisms and the Modulation of Pain," the newest volume in the "Advances in Pharmacology" series, presents the pharmacological mechanisms and the modulation of pain. With a variety of chapters and the best authors in the field, this volume is an essential resource for pharmacologists, immunologists, and biochemists alike. Contains contributions from the best authors in the field of pharmacology that focus on the pharmacological mechanisms and modulation of painProvides an essential resource for pharmacologists, immunologists, and biochemists
Описание: Patients with peripheral vascular disease (PVD) are at increased risk of death when compared with age-matched healthy controls. They are also, whether symptomatic or not, six times more likely to die within ten years when compared to patients without the disease. This excess mortality exists even if coronary artery disease is not clinically present, and makes the treatment of PVD a highly important and pressing topic. In this fully up-to-date text, Dr. Mukherjee and his excellent team of twenty-one contributors present the reader with all of the currently available clinical information for treating PVD patients effectively.
Описание: This set of six volumes provides a systematic and standardized description of 23,033 chemical components isolated from 6,926 medicinal plants, collected from 5,535 books/articles published in Chinese and international journals. A chemical structure with stereo-chemistry bonds is provided for each chemical component, in addition to conventional information, such as Chinese and English names, physical and chemical properties. It includes a name list of medicinal plants from which the chemical component was isolated. Furthermore, abundant pharmacological data for nearly 8,000 chemical components are presented, including experimental method, experimental animal, cell type, quantitative data, as well as control compound data. The seven indexes allow for complete cross-indexing. Regardless whether one searches for the molecular formula of a compound, the pharmacological activity of a compound, or the English name of a plant, the information in the book can be retrieved in multiple ways.
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