Slonim Woods 9, Levin, Daniel Barban

Автор: Barban Judith
Название: Meredith`s Wolf
ISBN: 0985925590 ISBN-13(EAN): 9780985925598
Издательство: Неизвестно
Цена: 2233.00 р.
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Автор: Barban Judith
Название: Crown Jewels
ISBN: 0991433203 ISBN-13(EAN): 9780991433209
Издательство: Неизвестно
Цена: 1723.00 р.
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Автор: Mills Melinda C., Barban Nicola, Tropf Felix C.
Название: An Introduction to Statistical Genetic Data Analysis
ISBN: 0262538385 ISBN-13(EAN): 9780262538381
Издательство: Random House (USA)
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Цена: 5518.00 р.
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Описание: A comprehensive introduction to modern applied statistical genetic data analysis, accessible to those without a background in molecular biology or genetics.

Human genetic research is now relevant beyond biology, epidemiology, and the medical sciences, with applications in such fields as psychology, psychiatry, statistics, demography, sociology, and economics. With advances in computing power, the availability of data, and new techniques, it is now possible to integrate large-scale molecular genetic information into research across a broad range of topics. This book offers the first comprehensive introduction to modern applied statistical genetic data analysis that covers theory, data preparation, and analysis of molecular genetic data, with hands-on computer exercises. It is accessible to students and researchers in any empirically oriented medical, biological, or social science discipline; a background in molecular biology or genetics is not required.

The book first provides foundations for statistical genetic data analysis, including a survey of fundamental concepts, primers on statistics and human evolution, and an introduction to polygenic scores. It then covers the practicalities of working with genetic data, discussing such topics as analytical challenges and data management. Finally, the book presents applications and advanced topics, including polygenic score and gene-environment interaction applications, Mendelian Randomization and instrumental variables, and ethical issues. The software and data used in the book are freely available and can be found on the book's website.