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Protein Interactions As Targets In Drug Discovery,121, Donev, Rossen


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Автор: Donev, Rossen
Название:  Protein Interactions As Targets In Drug Discovery,121
ISBN: 9780128168462
Издательство: Elsevier Science
Классификация:





ISBN-10: 0128168463
Обложка/Формат: Hardcover
Страницы: 264
Вес: 0.58 кг.
Дата издания: 01.05.2020
Серия: Advances in protein chemistry and structural biology
Язык: English
Размер: 229 x 152 x 19
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Protein Interactions as Targets in Drug Discovery, Volume 121, is dedicated to the design of therapeutics, both experimental and computational, that target protein interactions. Chapters in this new release include Trends in structure based drug design with protein targets, From fragment- to peptide-protein interaction: addressing the structural basis of binding using Supervised Molecular Dynamics (SuMD), Protein-protein and protein-ligand interactions: identification of potential inhibitors through computational analysis, Aromatic-aromatic interactions in protein-drug and protein-protein interactions, Role of protein-protein interaction in allosteric drug design within the human methyltransferome, and much more.



Protein-Protein Interactions as New Drug Targets

Автор: Enno Klussmann; John Scott
Название: Protein-Protein Interactions as New Drug Targets
ISBN: 3642091946 ISBN-13(EAN): 9783642091940
Издательство: Springer
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Цена: 56993.00 р.
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Описание: This book covers therapeutically relevant protein-protein interactions, focusing on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the field are included.

Regulation of Plasma Low Density Lipoprotein Levels Biopharmacological Regulation of Protein Phosphorylation Calcium-Activated Neutral Protease Microbial Iron Transport Pharmacokinetic Drug Interactions

Автор: William R. Bartle; Volker Braun; John M. Dietschy;
Название: Regulation of Plasma Low Density Lipoprotein Levels Biopharmacological Regulation of Protein Phosphorylation Calcium-Activated Neutral Protease Microbial Iron Transport Pharmacokinetic Drug Interactions
ISBN: 3642729045 ISBN-13(EAN): 9783642729041
Издательство: Springer
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Цена: 12196.00 р.
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Описание: Since it has been demonstrated that reducing the steady-state plasma LDL-cholesterol concentration produces a proportional decrease in the risk of developing atherosclerosis 2), a major effort is now underway to develop safe and effective lipid lowering agents.

Antibiotic Drug Discovery: New Targets and Molecular Entities

Название: Antibiotic Drug Discovery: New Targets and Molecular Entities
ISBN: 1782624244 ISBN-13(EAN): 9781782624240
Издательство: Royal Society of Chemistry
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Цена: 26770.00 р.
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Описание: This book identifies and elaborates the most recent and compelling strategies for antibiotic drug discovery with a primary focus on new targets, mechanisms and molecular entities.

New Developments in Lipid-Protein Interactions and Receptor Function

Автор: K.W.A. Wirtz; Lester Packer; J.?. Gustafsson; A.E.
Название: New Developments in Lipid-Protein Interactions and Receptor Function
ISBN: 1461362393 ISBN-13(EAN): 9781461362395
Издательство: Springer
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Цена: 6097.00 р.
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Описание: Proceedings of a NATO ASI held in Spetsai, Greece, August 16-27, 1992

DNA-Protein Interactions

Автор: A. Travers
Название: DNA-Protein Interactions
ISBN: 0412259907 ISBN-13(EAN): 9780412259906
Издательство: Springer
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Цена: 13677.00 р.
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Описание: An exploration of the molecular interactions involved in the binding of proteins to DNA and the manipulation of DNA by proteins in such processes as recombination, transcription and topomerization. The structural and mechanistic bases of these phenomena in bacteria and higher organisms is stressed.

Protein-Protein Interactions

Автор: Rainer Jaenicke; E. Helmreich
Название: Protein-Protein Interactions
ISBN: 3642654584 ISBN-13(EAN): 9783642654589
Издательство: Springer
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Цена: 15855.00 р.
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Описание: The present volume contains the proceedings of the 23rd Mos- bach Colloquium on "Protein-Protein Interactions." It includes the paper by Prof. S. LIFSON who unfortunately was unable to attend. Discussions were included whenever possible in order to make the complete proceedings accessible to the future reader. The colloquium was generously supported by the firms who are corporate members of the Gesellschaft fur Biologische Chemie. Dr. W. B. GRATZER and Dr. L. JAENICKE, as weIl as some of the invited speakers, were a tremendous help in preparing the program and we wish to thank them for their helpfuI suggestions and advice. Our appreciation extends to Prof. E. AUHAGEN and Prof. H. GIBIAN, and their secretaries, who shared the burden of organizing the colloquium. In addition, we wish to express our gratitude to Springer-Ver- Iag, and especially to Dr. H. MAYER-KAUPP for editoriaI help and for the rapid publication of this volume. We hope that the reader, Iike the audience in the Mosbach market hall, will gain an impression of the present state of protein research and of the way in which intermolecular interactions hold specific implications for the structure and function of proteins. Regensburg and Wurzburg, autumn 1972 R. JAENICKE E. HELMREICH Contents Introduction. R. JAENICKE (Regensburg) 1 Molecular Forees. S. LIFSON (Rehovot) ................... 3 Structure, Function and Dynamics of a ReguIatory Enzyme: Aspartate Transcarbamylase. H. K. SCHACHMAN (Berkeley) 17 Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 54 . . . . . . . . . . . . . .

DNA-Protein Interactions

Автор: Beno?t P. Leblanc; S?bastien Rodrigue
Название: DNA-Protein Interactions
ISBN: 1493928767 ISBN-13(EAN): 9781493928767
Издательство: Springer
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Цена: 18294.00 р.
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Описание: DNA-Protein Interactions


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