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G Protein-Coupled Receptor Signaling, Mario Tiberi


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Цена: 21953.00р.
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Автор: Mario Tiberi
Название:  G Protein-Coupled Receptor Signaling
ISBN: 9781493991204
Издательство: Springer
Классификация:





ISBN-10: 1493991205
Обложка/Формат: Hardcover
Страницы: 406
Вес: 1.01 кг.
Дата издания: 2019
Серия: Methods in Molecular Biology
Язык: English
Издание: 1st ed. 2019
Иллюстрации: 71 illustrations, color; 16 illustrations, black and white; xv, 406 p. 87 illus., 71 illus. in color.
Размер: 254 x 178 x 24
Читательская аудитория: Professional & vocational
Основная тема: Life Sciences
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This detailed volume assembles comprehensive protocols to assist with the study of structural, molecular, cell biological, and in vivo facets of GPCRs, and to enable the development of experimental tools for screening novel GPCR drugs. Sections explore the tweaking of ligands, bioluminescence and FRET approaches, specific GPCR signaling properties, as well as visualization of subcellular compartmentalization. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, G Protein-Coupled Receptor Signaling: Methods and Protocols serves as an ideal reference for life scientists working in a variety of research fields including molecular pharmacology, cell and developmental biology, brain behavior and physiology, drug development and screening.
Chapter 4 is available open access under a CC BY 4.0 license via link.springer.com.

Дополнительное описание: Assessment of Conformational State Transitions of Class B GPCRs Using Molecular Dynamics.- Molecular Dynamic Simulations to Probe Water Permeation Pathways of GPCRs.- Expression and Purification of a Functional E. coli 13CH3-Methionine-Labeled Thermostabl



G Protein-Coupled Receptor Signaling in Plants

Автор: Mark P. Running
Название: G Protein-Coupled Receptor Signaling in Plants
ISBN: 1627035311 ISBN-13(EAN): 9781627035316
Издательство: Springer
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Цена: 12805.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This Methods in Molecular Biology book describes techniques used in the study of small GTPases and related proteins. Includes a chapter on bioinformatics approaches, plus reproducible protocols, materials lists, practical tips and troubleshooting advice.

G Protein-Coupled Receptor Signaling in Plants

Автор: Mark P. Running
Название: G Protein-Coupled Receptor Signaling in Plants
ISBN: 1493962167 ISBN-13(EAN): 9781493962167
Издательство: Springer
Рейтинг:
Цена: 12805.00 р.
Наличие на складе: Есть у поставщика Поставка под заказ.

Описание: This Methods in Molecular Biology book describes techniques used in the study of small GTPases and related proteins. Includes a chapter on bioinformatics approaches, plus reproducible protocols, materials lists, practical tips and troubleshooting advice.

G Protein-Coupled Receptor Genetics

Автор: Craig W. Stevens
Название: G Protein-Coupled Receptor Genetics
ISBN: 1627037780 ISBN-13(EAN): 9781627037785
Издательство: Springer
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Цена: 20733.00 р.
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Описание: G Protein-Coupled Receptor Genetics: Research and Methods in the Post-Genomic Era features practical techniques inspired by the fast moving GPCR field.

Functional Selectivity of G Protein-Coupled Receptor Ligands

Автор: Kim Neve
Название: Functional Selectivity of G Protein-Coupled Receptor Ligands
ISBN: 1493961160 ISBN-13(EAN): 9781493961160
Издательство: Springer
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Цена: 22796.00 р.
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Описание: In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon.

G-Protein-Coupled Receptor Dimers

Автор: Katharine Herrick-Davis; Graeme Milligan; Giuseppe
Название: G-Protein-Coupled Receptor Dimers
ISBN: 3319601725 ISBN-13(EAN): 9783319601724
Издательство: Springer
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Цена: 24392.00 р.
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Описание: G-protein-coupled receptors (GPCRs) are believed to be the largest family of membrane proteins involved in signal transduction and cellular responses.

G Protein-Coupled Receptor Kinases

Автор: Gurevich
Название: G Protein-Coupled Receptor Kinases
ISBN: 1493937960 ISBN-13(EAN): 9781493937967
Издательство: Springer
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Цена: 17074.00 р.
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Описание: This collection explores up-to-date descriptions of known G protein-coupled receptor kinase (GRK)-dependent mechanisms, both associated with G protein-coupled receptor (GPCR) functions and the receptor-independent. The chapters cover a wide range of studies from invertebrates to humans, with sections of the volume covering GRK structure, mechanisms of activation, and interaction with GPCRs, GRKs in cell signaling, as well as physiological and pathophysiological mechanisms regulated by GRKs. Written for the Methods in Pharmacology and Toxicology series, this book features the kind of practical detail necessary for success in the laboratory.

Authoritative and timely, G Protein-Coupled Receptor Kinases features the kind of comprehensive mechanistic elucidation of GRK functions and their regulation in cells necessary for a better understanding of cell biology as well as for devising novel research approaches and therapeutic strategies.
G Protein-Coupled Receptor Screening Assays

Автор: Duarte Miguel F. Prazeres; Sofia Aires M. Martins
Название: G Protein-Coupled Receptor Screening Assays
ISBN: 1493923358 ISBN-13(EAN): 9781493923359
Издательство: Springer
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Цена: 17074.00 р.
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Описание: This volume explores the considerable efforts that have been directed towards the development of G Protein-Coupled Receptors (GPCR) screening assays in order to disclose GPCR acting compounds, elucidate signaling mechanisms or evaluate compound`s efficacy.

G Protein-Coupled Receptors: Signaling, Trafficking and Regulatio

Автор: Arun K. Shukla
Название: G Protein-Coupled Receptors: Signaling, Trafficking and Regulatio
ISBN: 0128035951 ISBN-13(EAN): 9780128035955
Издательство: Elsevier Science
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Цена: 21222.00 р.
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Описание:

"G-Protein-Coupled Receptors: Signaling, Trafficking, and Regulation," a new volume in the "Methods in Cell Biology" series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in G-Protein-Coupled Receptors, and includes sections on such topics signaling, trafficking and regulation.
Covers the increasingly appreciated cell biology field of G-protein-coupled receptorsIncludes both established and new technologiesContributed by experts in the fieldCovers topics such as signaling, trafficking, and regulation

G Protein-Coupled Receptors: From Structure to Function

Название: G Protein-Coupled Receptors: From Structure to Function
ISBN: 1849731837 ISBN-13(EAN): 9781849731836
Издательство: Royal Society of Chemistry
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Цена: 26926.00 р.
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Описание: This book considers the relationship between structure and function in G protein-coupled receptors (GPCRs) and the implications for drug design.

From Structure To Clinical Development: Allosteric Modulation Of G Protein-Coupled Receptors,88

Автор: Langmead, Christopher J.
Название: From Structure To Clinical Development: Allosteric Modulation Of G Protein-Coupled Receptors,88
ISBN: 0128201878 ISBN-13(EAN): 9780128201879
Издательство: Elsevier Science
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Цена: 32002.00 р.
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Описание:

From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure‐based discovery and development of mGlu5 NAMs, and much more.

G Protein-Coupled Receptors - Modeling and Simulation

Автор: Marta Filizola
Название: G Protein-Coupled Receptors - Modeling and Simulation
ISBN: 9400774222 ISBN-13(EAN): 9789400774223
Издательство: Springer
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Цена: 19377.00 р.
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Описание: G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses.

Oligomerization In Health And Disease: From Enzymes To G Protein-Coupled Receptors,169

Автор: Giraldo, Jesus
Название: Oligomerization In Health And Disease: From Enzymes To G Protein-Coupled Receptors,169
ISBN: 0128179295 ISBN-13(EAN): 9780128179291
Издательство: Elsevier Science
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Цена: 21054.00 р.
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Описание:

Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scientific importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine β-synthase, and Oligomerization of Porphobilinogen Synthase.


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