Автор: Bright, Jo-anne Coble, Michael Название: Forensic dna profiling ISBN: 0367029022 ISBN-13(EAN): 9780367029029 Издательство: Taylor&Francis Рейтинг: Цена: 21437.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Forensic DNA Profiling is a hands-on step-by-step guide to teach the forensic DNA community how to interpret DNA mixtures, how to assign a Likelihood Ratio, and how to use the subsequent Likelihood Ratio when reporting interpretation conclusions.
Автор: Grutzmann Robert, Pilarsky Christian Название: Cancer Gene Profiling: Methods and Protocols ISBN: 1493979973 ISBN-13(EAN): 9781493979974 Издательство: Springer Рейтинг: Цена: 15998.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Factors Affecting the Use of Human Tissues in Biomedical Research: Implications in the Design and Operation of a Biorepository Daniel S. Atherton, Katherine C. Sexton, Dennis Otali, Walter C. Bell, and William E. Grizzle
2. Tissue Microdissection Anja Rabien and Glen Kristiansen
3. Tissue Microarrays Ana-Maria Dancau, Ronald Simon, Martina Mirlacher, and Guido Sauter
4. Gene Expression Analysis in the Age of Mass Sequencing: An Introduction Christian Pilarsky, Lahiri Kanth Nanduri, and Janine Roy
5. Quantitative DNA Methylation in Cancer Ole Ammerpohl, Andrea Haake, Julia Kolarova, and Reiner Siebert
6. Single Nucleotide Polymorphism to Associate Cancer Risk Victoria Shaw, Katie Bullock, and William Greenhalf
7: Exosomes in Cancer Disease Margot Zцller
8: MicroRNAs (miRNAs) Profiling Lu Gao and Feng Jiang
9. Cancer Gene Profiling for Response Prediction B. Michael Ghadimi and Peter Jo
10. Target Gene Discovery for Novel Therapeutic Agents in Cancer Treatment Sanjay Tiwari, Ole Ammerpohl, and Holger Kalthoff
11. Application of Proteomics in Cancer Biomarker Discovery: GeLC-MS/MS Pedro R. Cutillas and Tatjana Crnogorac-Jurcevic
12. Meta-Analysis of Cancer Gene Profiling Data Janine Roy, Christof Winter, and Michael Schroeder
13. Reproducible, Scalable Fusion Gene Detection from RNA-Seq Vladan Arsenijevic and Brandi N. Davis-Dusenbery
14. Transcriptome Sequencing for the Detection of Chimeric Transcripts Hsueh-Ting Chu
Автор: Espina Virginia Название: Molecular Profiling: Methods and Protocols ISBN: 1493983601 ISBN-13(EAN): 9781493983605 Издательство: Springer Рейтинг: Цена: 18294.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
1. Tumor Staging and Grading: A Primer
Stacy M. Telloni
2. Innovations in Clinical Trial Design in the Era of Molecular Profiling
Julia D. Wulfkuhle, Alexander Spira, Kirsten H. Edmiston, and Emanuel F. Petricoin
3. Personalized Medicine: Ethical Aspects
G. Terry Sharrer 4. Antibody Validation by Western Blotting
Michele Signore, Valeria Manganelli and Alex Hodge
5. Scanning Electron Microscopy Sample Preparation and Imaging
Jenny Ngoc Tran Nguyen and Amanda M. Harbison
Claudius Mueller, Michael G. Harpole, and Virginia Espina
7. Application of Hydrogel Nanoparticles for the Capture, Concentration, and Preservation of Low-Abundance Biomarkers
Ruben Magni and Alessandra Luchini
8. Using Laser Capture Microdissection to Isolate Cortical Laminae in Non-human Primate Brain
Brian A. Corgiatand Claudius Mueller
9. Western Blot Techniques
Brianna Kim
10. ELISA for Monitoring Nerve Growth Factor
Justin B. Davis
11. Reverse Phase Protein Microarrays
Elisa Baldelli, Valerie Calvert, Alex Hodge, Amy VanMeter, Emanuel F. Petricoin III, and Mariaelena Pierobon
12. Clustering and Network Analysis of Reverse-Phase Protein Array Data
Adam Byron
13. PCR: Identification of Genetic Polymorphisms
Amanda M. Harbison and Jenny Ngoc Tran Nguyen
14. Microsatellite Analysis for Identification of Individuals Using Bone from the Extinct Steller's Sea Cow (Hydrodamalis gigas)
Jeffery F. Warner, Michael G. Harpole, and Lorelei D. Crerar
15. Somatic DNA Mutation Analysis
Anthony O'Grady and Robert Cummins
16. Optimization of Immunostaining for Prospective Image Analysis
Scott M. Lawrence and Yelena G. Golubeva
17. Fluorescence in situ Hybridization of Cells, Chromosomes, and Formalin Fixed Paraffin Embedded Tissues
Ahmad Alamri, Jun Yeb Nam, and Jan K. Blancato
18. High-Resolution Image Stitching as a Tool to Assess Tissue-Level Protein Distribution and Localization
Bryan A. Millis and Matthew J. Tyska
19. Mass Spectrometry Based Biomarker Discovery
Weidong Zhou, Emanuel F. Petricoin III, and Caterina Longo
20. Quantitative Mass Spectrometry by Isotope-Dilution and Multiple Reaction Monitoring (MRM)
Paul Russo, Brian L. Hood, Nicholas W. Bateman, Thomas P. Conrads
21. LC-Mass Spectrometry for Metabolomics Allyson L. Dailey
22. Metabolomic Bioinformatic Analysis
Allyson L. Dailey
23. Stable Isotope Quantitative N-glycan Analysis by Liquid Separation Techniques and Mass Spectrometry
Stefan Mittermayr, Simone Albrecht, Csaba Vбradi, Silvia Millбn-Martнn, and Jonathan Bones
24. Grant Writing Tips for Translational Research
Lindsay Wescott, Michael Laskofski, Donna Senator, and Carly Curran
25. Inventions and Patents: A Practical Tutorial
Hina Mehta, Lille Tidwell, and Lance A. Liotta
26. Product Development and Commercialization of Diagnostic or Life Science Products for Scientists and Researchers
Meghan M. Alonso
Название: Metabolic Profiling: Disease and Xenobiotics ISBN: 1849731632 ISBN-13(EAN): 9781849731638 Издательство: Royal Society of Chemistry Рейтинг: Цена: 27720.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This exemplary new book highlights applications of multivariate techniques in the areas of drug therapy and toxicology, cancer, obesity and diabetes, as well as outlining applications to cardiovascular, infectious, inflammatory and oral diseases in detail.
Автор: Simone Mocellin Название: Microarray Technology and Cancer Gene Profiling ISBN: 1441922989 ISBN-13(EAN): 9781441922984 Издательство: Springer Рейтинг: Цена: 24394.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Given the revolutionary implications that the use of this technology might have in the clinical management of cancer patients, the principles of DNA array-based tumor gene profiling must be clearly understood for the data to be correctly interpreted and appreciated.
Автор: Binnig, Gerd Huss, Ralf Schmidt, Gunter Название: Tissue phenomics: profiling cancer patients for treatment decisions ISBN: 981477488X ISBN-13(EAN): 9789814774888 Издательство: Taylor&Francis Рейтинг: Цена: 21284.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the age of digitization our society is transformed into a new state. In particular, machine intelligence dramatically elevates our capability to create and digest information. Naturally, healthcare is also impacted by this trend and will even be more transformed into a informatic driven discipline in the future. In the most important area of histo-pathology, the interpretation of tissue slices from cancer patients, informatics will have an early and huge impact on treatment decisions and probably will act as the leading discipline for this transformation in medicine. Tissue Phenomics provides a comprehensive methodology aiming at the discovery of the most accurate tissue-based decision support algorithm by close integration of assay development, image analysis and bioinformatics, and optimization feedback loops. In this book the methodology of Tissue Phenomics and its benefits and wealth’s are described. The different components of Tissue Phenomics are explained in the different chapters. In the chapters 2 to 4 of this book different authors describe various approaches on how to convert the wealth of tissue slide pixel data into mineable information using knowledge-based and data-driven image analysis methods. Subsequently, the datafication of images and the bioinformatics part plays a crucial role in generating prognostic and predictive models for disease progression. The integration of other data sources such as genomics, radiomics and patient related information is also important and is described as well. As discussed in chapters 5 and 6, these models may classify patients in distinct groups such as those responding to a given therapy. Since Tissue Phenomics provides a huge set of potentially prognostic features (phenes), one focus of both chapters is robust feature selection methods by advanced Monte-Carlo cross validation algorithms. In chapter 7 we discuss multiple application examples of Tissue Phenomics in academic and commercial settings and its tremendous impact to advances in biomedical sciences. Building on the successes in research, chapters 8 and 9 discuss applications in clinical environments and provide a flavor to the future envision in chapter 10, where tissue datafication and subsequent patient profiling is part of every routine examination, with the goal to best match patients with the most successful therapy, as predicted by tissue phenes.
Название: Risk Profiling in Genomics ISBN: 0367356694 ISBN-13(EAN): 9780367356699 Издательство: Taylor&Francis Рейтинг: Цена: 23734.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume presents the ethical implications of risk information as related to genetics and other health data for policy decisions at clinical, research and societal levels. It will be of great interest to students and scholars of theoretical and clinical medical ethics, medical sociology, risk communication and ethics of risk.
Автор: Mathias Munschauer Название: High-Resolution Profiling of Protein-RNA Interactions ISBN: 3319368486 ISBN-13(EAN): 9783319368481 Издательство: Springer Рейтинг: Цена: 12537.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The book describes how the study of a single RNA-binding protein and its interaction sites led to the development of the novel `protein occupancy profiling` technology that for the first time captured the mRNA sequence space contacted by the ensemble of expressed RNA binders.
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