Charney, Dennis S.; Nestler, Eric J.; Sklar, Pamel Charney & Nestler`s Neurobiology of Mental Illness 9780190681425

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Автор: Charney, Dennis S.; Nestler, Eric J.; Sklar, Pamel
Название: Charney & Nestler`s Neurobiology of Mental Illness
ISBN: 9780190681425
Издательство: Oxford Academ
Классификация:

Неврология и клиническая нейрофизиология

Психиатрия

ISBN-10: 019068142X
Обложка/Формат: Hardcover
Страницы: 1024
Вес: 3.00 кг.
Дата издания: 28.02.2018
Язык: English
Издание: 5 revised edition
Размер: 284 x 224 x 46
Читательская аудитория: Practicing psychiatrists and psychologists Academic faculty in psychiatry and psychology Resident trainees in psychiatry Intern trainees in psychology Advanced medical and graduate students
Основная тема: Psychiatry
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Англии
Описание: In the years following publication of the DSM-5(R), the field of psychiatry has seen vigorous debate between the DSMs more traditional, diagnosis-oriented approach and the NIMHs more biological, dimension-based RDoC (research domain criteria) approach. Charney & Nestlers Neurobiology of
Mental Illness is an authoritative foundation for translating information from the laboratory to clinical treatment, and its fifth edition extends beyond this reference function to acknowledge and examine the controversies, different camps, and thoughts on the future of psychiatric diagnosis.

In this wider context, this book provides information from numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. Sections and chapters are edited and authored by experts at the top of their fields. No
other book distills the basic science and underpinnings of mental disorders-and highlights practical clinical significance-to the scope and breadth of this classic text.

In this edition, Section 1, which reviews the methods used to examine the biological basis of mental illness in animal and cell models and in humans, has been expanded to reflect critically important technical advances in complex genetics (including powerful sequencing technologies and related
bioinformatics), epigenetics, stem cell biology, optogenetics, neural circuit functioning, cognitive neuroscience, and brain imaging. This range of established and emerging methodologies offer groundbreaking advances in our ability to study the brain as well as unique opportunities for the
translation of preclinical and clinical research into badly needed breakthroughs in our therapeutic toolkit.

Sections 2 through 7 cover the neurobiology and genetics of major psychiatric disorders: psychoses (including bipolar disorder), mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood onset. Also covered within these sections is a summary of current
therapeutic approaches for these illnesses as well as the ways in which research advances are now guiding the search for new treatments. Each of these parts has been augmented in several different areas as a reflection of research progress.

The last section, Section 8, reconfigured in this new edition, now focuses on diagnostic schemes for mental illness. This includes an overview of the unique challenges that remain in diagnosing these disorders given our still limited knowledge of disease etiology and pathophysiology. The section
then provides reviews of DSM-5(R), which forms the basis of psychiatric diagnosis in the United States for all clinical work, and of RDoC, which provides an alternative perspective on diagnosis in heavy use in the research community. Also included are chapters on future efforts toward precision and
computational psychiatry, which promise to someday align diagnosis with underlying biological abnormalities.

Дополнительное описание: Section 1: Emerging and Established Technologies; 1. Genetic Methodologies and Applications; Shaun M. Purcell; 2. Network Methods for Elucidating the Complexity of Common Human Diseases; Eric E. Schadt; 3. The Human Brain and its Epigenome; Andrew Chess

Charney & Nestler`s Neurobiology of Mental Illness, Charney, Dennis S.; Nestler, Eric J.; Sklar, Pamel