Parkinson`s Disease and Movement Disorders, Charles H. Adler; J. Eric Ahlskog
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 30624.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Phyllis A. Dennery; Giuseppe Buonocore; Ola Didrik Название: Perinatal and Prenatal Disorders ISBN: 1493914049 ISBN-13(EAN): 9781493914043 Издательство: Springer Рейтинг: Цена: 19514.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This authoritative volume describes the role of free radicals and antioxidants in prenatal and perinatal disorders currently explored in clinical and pre-clinical trials. In twenty-two inclusive chapters, the book covers the gamut of oxidative stress and its relation to a variety of factors, including fertility, metabolism, redox biomarkers, antioxidant defense and protection, gene polymorphisms, angiogenesis, cell signaling, mutations and oxidative damage involving lipids, proteins and nucleic acids, membrane trafficking, inflammation, mitochondrial dysfunction, alterations in immunological function, hypoxia, and post-natal stressors. This comprehensive source will keep clinicians and research scientists up-to-date on translational research into medical applications. Perinatal and Prenatal Disorders is a significant addition to the well-known Oxidative Stress in Applied Basic Research and Clinical Practice series.
Автор: Karlis Adamsons Название: Diagnosis and Treatment of Fetal Disorders ISBN: 3642461743 ISBN-13(EAN): 9783642461743 Издательство: Springer Рейтинг: Цена: 12196.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Later, the sounds of the fetal heart heard by auscultation and the varia- tions in its rate became the single important means by which the welfare of the fetus might be roughly determined and threats to his survival per- haps detected.
Автор: Toshiyuki Fukada; Taiho Kambe Название: Zinc Signals in Cellular Functions and Disorders ISBN: 4431561803 ISBN-13(EAN): 9784431561804 Издательство: Springer Рейтинг: Цена: 17096.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book describes the crucial role of "zinc signals" in biological processes on a molecular and physiological basis, discussing future directions and questions underlying this unique phenomenon.
Автор: Phyllis A. Dennery; Giuseppe Buonocore; Ola Didrik Название: Perinatal and Prenatal Disorders ISBN: 1493953680 ISBN-13(EAN): 9781493953684 Издательство: Springer Рейтинг: Цена: 18237.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: "Humana Press is a brand of Springe"--Tp verso.
Автор: Emanuele Albano; Maurizio Parola Название: Studies on Hepatic Disorders ISBN: 3319155385 ISBN-13(EAN): 9783319155388 Издательство: Springer Рейтинг: Цена: 24392.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines the current state of free radical biology as it impacts on hepatic disorders. It takes a thorough look at the relationship of oxidative stress in acute and chronic disease and takes into account factors like: redox biomarkers; antioxidant defense and protection; cell signaling, mutations; oxidative damage involving lipids, proteins and nucleic acids; membrane trafficking, inflammation, mitochondrial dysfunction, alterations in immunological function and toxicology and hypoxia. Studies on Hepatic Disorders, the latest volume in the Oxidative Stress in Basic Research and Clinical Practice series, provides a comprehensive look at liver topics. It is organized into four sections, each one thoroughly covering its topic and consisting of chapters written by recognized field leaders. Section One, covers basic principles including redox signaling, antioxidant defenses, nitric oxide, oxidative mechanisms in senescence and regeneration and the detection of oxidative stress. Section Two, explores Pathophysiology. It ranges from cell damage to fibrogenic response as broken out in chapters on hepatocellular injury, mitochondrial damage, unfolded protein response and autophagy, inflammation, ischemia-reperfusion injury and finally, fibrogenesis. Sections Three and Four cover specific diseases and cancer, respectively. Most of the chapters focus on diseases including acute failure, alcoholic disease, viral hepatitis, iron overload, autoimmune disease, Wilson’s disease and more, while the chapters on cancer round out the book.
Автор: Donev, Rossen Название: Stress and Inflammation in Disorders,108 ISBN: 0128123885 ISBN-13(EAN): 9780128123881 Издательство: Elsevier Science Рейтинг: Цена: 20043.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:
Stress and Inflammation in Disorders, Volume 108, the newest volume in this ongoing series, brings forth new information on protocols and analysis of proteins. This volume covers the latest on Oxidative Stress: Love and Hate History in the Central Nervous System, Neuroinflammation in Alzheimer's Disease: The Preventive and Therapeutic Potential of Polyphenolic Nutraceuticals, Inflammation in Epileptic Encephalopathies, A Computational Approach to Identify the Biophysical and Structural Aspect of Methylenetetrahydrofolate Reductase (MTHFR) Mutations (A222V, E429A and R594Q) Leading to Schizophrenia, and Analyzing the Effect of V66M Mutation in BDNF in Causing MOOD Disorders- A Computational Approach.
Each release in the Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.
Provides cutting-edge developments in protein chemistry and structural biology
Features new information about protocols and analysis of proteins
Contains chapters written by authorities in their respective fields
Targeted to a wide audience of researchers, specialists, and students
Автор: Heinrich Sauer; Ajay M. Shah; Francisco R. M. Laur Название: Studies on Cardiovascular Disorders ISBN: 1617797073 ISBN-13(EAN): 9781617797071 Издательство: Springer Рейтинг: Цена: 31915.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Preface Contributor's List Chapters: 1) The evolving concept of oxidative stress Denise de Castro Fernandes, Diego Bonatto, Francisco R. M. Laurindo 2) Mechanisms of redox signaling in cardiovascular disease Rebecca L. Charles, Joseph R. Burgoyne and Philip Eaton 3) Reactive oxygen and nitrogen species in cardiovascular differentiation of stem cells Heinrich Sauer and Maria Wartenberg 4) Reactive Oxygen Species (ROS) and the sensory neurovascular component Rabea Graepel BSc, Jennifer Victoria Bodkin BSc, MRes, & Susan Diana Brain BSc, PhD 5) Mitochondrial Reactive Oxygen Species in Myocardial Pre- and Post-Conditioning Ariel R. Cardoso, Bruno B. Queliconi* and Alicia J. Kowaltowski 6) Coenzyme Q9/Q10 and Healthy Heart Samarjit Das, Somak Das and Dipak K. Das 7) Oxidative and proteolytic stress in homocysteine associated cardiovascular diseases Karni S. Moshal, Munish Kumar, Neetu Tyagi, Paras Kumar Mishra, Saumi Kundu, Suresh C. Tyagi 8) Functional studies of NADPH oxidases in human vasculature Tomasz J Guzik 9) Relationship of the CYBA gene polymorphisms with oxidative stress and cardiovascular risk Guillermo Zalba, PhD and Javier Dнez, MD, PhD 10) Redox-related genetic markers of cardiovascular diseases Christian Delles, MD, and Anna F. Dominiczak, MD 11) NADPH oxidases and blood-brain barrier dysfunction in stroke Timo Kahles, MD, Sabine Heumьller and Ralf P. Brandes, MD 12) Smoking-Induced Oxidative Stress in the Pathogenesis of Cardiovascular Diseases David Bernhard PhD 13) Oxidative Stress in Vascular Aging Anna Csiszar, MD, PhD and Zoltan Ungvari, MD, PhD 14) Oxidative Stress and Cardiovascular Disease in Diabetes Mellitus Divya Gupta, Kathy K. Griendling and W. Robert Taylor 15) Reactive Oxygen Species, Oxidative Stress and Hypertension Rhian M Touyz MD, PhD, Andreia Chignalia, MSc, Mona Sedeek PhD 16) Peripartum cardiomyopathy: Role of STAT-3 and reactive oxygen species Denise Hilfiker-Kleiner, PhD, Arash Haghikia, MD, andAndres Hilfiker, PhD 17) Oxidative stress and inflammation after coronary angiography Raymond Farah MD 18) Oxidative Stress in Cardiac Transplantation Galen M. Pieper, Ph.D. and Ashwani K. Khanna, Ph.D 19) Oxidative Stress and Atrial Fibrillation Ali A. Sovari and Samuel C. Dudley, Jr. 20) Oxidative stress and the anti-oxidative capacity in myocardial infarction Yao Sun, MD, Ph.D. 21) Oxidative Stress and Redox Signalling in Cardiac Remodelling Min Zhang MD, PhD, Alex Sirker MRCP and Ajay M Shah MD, FmedSci 22) Oxidative Stress and Cardiovascular Fibrosis Subramanian Pennathur, Louise Hecker, and Victor J. Thannickal 23) Oxidative Risk Factors for Cardiovascular Disease in Women M. Gago-Dominguez, Xuejuan Jiang, J. Esteban Castelao 24) Protective effects of food on cardiovascular diseases Alfonso Giovane, Biol.D., Ph.D., and Claudio Napoli, M.D., Ph.D., MBEth. 25) Novel Synthetic Antioxidants and Nitrated Lipids: From Physiology to Therapeutic Implications Gloria V. Lуpez, PhD and Homero Rubbo, PhD 26) Thioredoxin in the cardiovascular system - towards a thioredoxin-based anti-oxidative therapy Bradford C. Berk 27) The protective effect of melatonin on the heart Amanda Lochner 28) Exercise Induced cardioprotection: Overview with an emphasis on the role of anti-oxidants Karyn L. Hamilton and John C. Quindry 29) Antioxidative properties of statins in the heart Oliver Adam MD, Ulrich Laufs MD
Автор: Arturo Leone; Julian F.B. Mercer Название: Copper Transport and Its Disorders ISBN: 0306460459 ISBN-13(EAN): 9780306460456 Издательство: Springer Рейтинг: Цена: 26711.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Covers the molecular and cellular biology of copper transport, with an emphasis on copper based diseases, especially the genetic disorder Menkes disease.
Автор: Maria Jose Alcaraz; Oreste Gualillo; Olga S?nchez- Название: Studies on Arthritis and Joint Disorders ISBN: 1489988823 ISBN-13(EAN): 9781489988829 Издательство: Springer Рейтинг: Цена: 20123.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This next volume in our established series proposes to systematically review the basic science and clinical knowledge of the role of free radicals and antioxidants, collectively known as “oxidative stress”, in the pathology of arthritis and other joint diseases. It will describe the most current diagnostic tools , laboratory methods and technology, to suggest ways of prevention and treatment and to emphasize the concept of the bench-to-bedside approach. The book will also provide specific coverage on emerging technology and medical applications including discussions of biomarkers and antioxidants as therapeutic agents and several more relevant aspects. In addition, the book will promote the concept of using biomarkers representative of oxidative stress reactions and free radical damage , as well as describe the effect of antioxidants in treating disease in clinical trials. The content will be valuable to researchers studying the development of arthritis/joint disease, and clinicians treating patients with these diagnoses.
Автор: Tsukahara Название: Studies on Pediatric Disorders ISBN: 149390678X ISBN-13(EAN): 9781493906789 Издательство: Springer Рейтинг: Цена: 24392.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume examines the role of oxidative stress in the pathology of numerous pediatric disorders.
Автор: Stephen Bondy; Kenneth Maiese Название: Aging and Age-Related Disorders ISBN: 1617796999 ISBN-13(EAN): 9781617796999 Издательство: Springer Рейтинг: Цена: 25075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book examines the interactive relationship between systems in the body, such as the nervous system and vascular system, that can enhance or sometimes limit cellular longevity. It details medical applications that should lead to improved health care.
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