Автор: Axel H. Sch?nthal Название: Checkpoint Controls and Cancer ISBN: 1617376035 ISBN-13(EAN): 9781617376030 Издательство: Springer Рейтинг: Цена: 17684.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In response to any of these assaults on the integrity of the genome, the activation of the network of checkpoint control pathways can lead to diverse cellular responses, such as cell cycle arrest, DNA repair, or elimination of the cell by cell death (apoptosis) if the damage cannot be repaired.
Автор: Siddik Название: Checkpoint Controls and Targets in Cancer Therapy ISBN: 1617796352 ISBN-13(EAN): 9781617796357 Издательство: Springer Рейтинг: Цена: 22796.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Checkpoint regulation is critical in understanding cancer development and cancer therapy. This book builds upon existing concepts of checkpoints and aims to expand our understanding of the inner workings of the critical checkpoint machinery.
Автор: Wei Dai Название: Checkpoint Responses in Cancer Therapy ISBN: 161737847X ISBN-13(EAN): 9781617378478 Издательство: Springer Рейтинг: Цена: 25075.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Checkpoint Responses in Cancer Therapy summarizes the advances made over the past 20 years, identifying components of cell-cycle checkpoints and their molecular regulation during checkpoint activation and validating the use of checkpoint proteins as targets for the development of anticancer drugs.
Описание: Further, the volume examines other agents, a number of cells, receptors and signaling molecules, that are also involved in the regulation of T-cell activation and extends the concept of immune checkpoints to "molecules and cells that negatively regulate T-cell activation".
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