Glutamine in Clinical Nutrition, Rajkumar Rajendram; Victor R. Preedy; Vinood B. Pa
Автор: D. H?ussinger; H. Sies Название: Glutamine Metabolism in Mammalian Tissues ISBN: 3642697569 ISBN-13(EAN): 9783642697562 Издательство: Springer Рейтинг: Цена: 13415.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Glutamine is a key aminoacid for the synthesis of numerous biologic- ally important compounds in mammalian cells and is a carrier form of ammonia. The advance in knowledge on the metabolic significance of this amino acid is presented in in-depth treatments by experts in this active research field. This includes the enzymology of glutamine synthe- tase and glutaminase activities in different mammalian organs, notably liver, kidney and brain; properties of glutamine transport across bio- logical membranes; role of glutamine metabolism in the liver, with emphasis on the recent discovery of intercellular heterogeneity with respect to enzyme distribution and its functional consequences for ammonia/urea metabolism and pH regulation; renal and intestinal glutamine metabolism; cerebral glutamine/ glutamate interrelationships; skeletal muscle; role of glutamine in cell culture; and finally the clinical aspects, including the new outlook of glutamine antagonists in cancer therapy as well as the role of glutamine in hepatic coma and encephalo- pathy. Some, but not all, of the contributors to this work attended the 48th Conference of the Gesellschaft fur Biologische Chemie on glutamine metabolism held in Gottingen, W. Germany, in September 1983. This conference was supported by the Stiftung Volkswagenwerk, Dr. H. Falk Foundation, Freiburg, and the J. Pfrimmer Co., Erlangen. The abstracts of the contributions to the conference were published in Hoppe-Seyler's Z. Physiol. Chem. 364,1237-125,6,1983, and this book is not intended as the proceedings of that meeting.
Автор: Arne Schousboe; Ursula Sonnewald Название: The Glutamate/GABA-Glutamine Cycle ISBN: 3319450948 ISBN-13(EAN): 9783319450940 Издательство: Springer Рейтинг: Цена: 20516.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Fundamental biochemical studies of basic brain metabolism focusing on the neuroactive amino acids glutamate and GABA combined with the seminal observation that one of the key enzymes, glutamine synthetase is localized in astroglial cells but not in neurons resulted in the formulation of the term “The Glutamate-Glutamine Cycle.” In this cycle glutamate released from neurons is taken up by surrounding astrocytes, amidated by the action of glutamine synthetase to glutamine which can be transferred back to the neurons. The conversion of glutamate to glutamine is like a stealth technology, hiding the glutamate molecule which would be highly toxic to neurons due to its excitotoxic action. This series of reactions require the concerted and precise interaction of a number of enzymes and plasma membrane transporters, and this volume provides in-depth descriptions of these processes. Obviously such a series of complicated reactions may well be prone to malfunction and therefore neurological diseases are likely to be associated with such malfunction of the enzymes and transporters involved in the cycle. These aspects are also discussed in several chapters of the book.
A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This book will be of particular importance for students as well as professionals interested in these fundamental processes involved in brain function and dysfunction.
Название: Clinical Nutrition 2 edition ISBN: 1405168102 ISBN-13(EAN): 9781405168106 Издательство: Wiley Рейтинг: Цена: 8229.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: * Offers a new chapter on Nutritional Screening and a student companion website * Cross-referenced across the series to enable the flow of learning and with illustrative case histories * Designed for use on nutrition courses throughout the world * Internationally-respected contributors and editors .
Автор: Patel Название: L-Arginine in Clinical Nutrition ISBN: 3319260073 ISBN-13(EAN): 9783319260075 Издательство: Springer Рейтинг: Цена: 20733.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Thistext presents the application of current nutritional knowledge by physiciansand dietitians and incorporates emerging fields of science and importantdiscoveries. It contains seven major sections.Section 1: Basic Processes at the Cellular Levels, Section 2: ArginineMetabolism and Functions, Section 3: Arginine Status in Cells Related to OrganDamage and Disease, Section 4: Arginine Status and Use in Healthy Individuals, Section5: Arginine and Diseases of the Gastrointestinal Tract, Section 6: Therapeuticuses of Arginine: Diabetes, Obesity and Cardiovascular Diseases and Section 7: Therapeutic Uses of Arginine: Cancer, WoundHealing and Infectious Disease.Writtenby authors of international and national standing, leaders in the field andtrendsetters, Arginine in Clinical Nutrition is essential reading fornutritionists and dietitians, public health scientists, doctors,epidemiologists, health care professionals of various disciplines, policymakers and marketing and economic strategists.
Автор: Nikolaos Katsilambros Название: Clinical Nutrition in Practice ISBN: 1405180846 ISBN-13(EAN): 9781405180849 Издательство: Wiley Рейтинг: Цена: 9496.00 р. Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: An easy-to-use book with questions on clinical nutrition clearly posed and answers based on real-life studies, this is a ready reference for the busy healthcare professional. Clinical Nutrition in Practice opens with introductory chapters on the basis of healthy nutrition, malnutrition and nutritional assessment.
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